Titre : Groupes témoins

Groupes témoins : Questions médicales fréquentes

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groupe témoin ?", "position": 2, "acceptedAnswer": { "@type": "Answer", "text": "Il permet d'évaluer l'effet d'un traitement en comparant les résultats avec ceux du groupe traité." } }, { "@type": "Question", "name": "Comment choisir un groupe témoin ?", "position": 3, "acceptedAnswer": { "@type": "Answer", "text": "Le choix doit se baser sur des critères d'inclusion similaires à ceux du groupe traité." } }, { "@type": "Question", "name": "Les groupes témoins sont-ils toujours nécessaires ?", "position": 4, "acceptedAnswer": { "@type": "Answer", "text": "Oui, ils sont essentiels pour établir des comparaisons valides dans les études cliniques." } }, { "@type": "Question", "name": "Les groupes témoins montrent-ils des symptômes ?", "position": 5, "acceptedAnswer": { "@type": "Answer", "text": "Non, ils ne reçoivent pas de traitement, donc ils ne présentent pas de symptômes liés au traitement." } }, { "@type": "Question", "name": "Comment les symptômes sont-ils évalués ?", "position": 6, "acceptedAnswer": { "@type": "Answer", "text": "Les symptômes sont évalués par des questionnaires ou des examens cliniques dans les deux groupes." } }, { "@type": "Question", "name": "Les groupes témoins aident-ils à la prévention ?", "position": 7, "acceptedAnswer": { "@type": "Answer", "text": "Oui, ils permettent d'évaluer l'efficacité des interventions préventives par comparaison." } }, { "@type": "Question", "name": "Comment les groupes témoins influencent-ils la prévention ?", "position": 8, "acceptedAnswer": { "@type": "Answer", "text": "Ils fournissent des données sur l'impact des mesures préventives en comparaison avec l'absence d'intervention." } }, { "@type": "Question", "name": "Quel type de traitement est comparé ?", "position": 9, "acceptedAnswer": { "@type": "Answer", "text": "Le traitement expérimental est comparé à un placebo ou à un traitement standard dans le groupe témoin." } }, { "@type": "Question", "name": "Comment les résultats sont-ils mesurés ?", "position": 10, "acceptedAnswer": { "@type": "Answer", "text": "Les résultats sont mesurés par des critères prédéfinis, comme l'amélioration des symptômes." } }, { "@type": "Question", "name": "Les complications sont-elles observées dans les groupes témoins ?", "position": 11, "acceptedAnswer": { "@type": "Answer", "text": "Les complications peuvent être observées, mais elles ne sont pas dues au traitement expérimental." } }, { "@type": "Question", "name": "Comment les complications sont-elles analysées ?", "position": 12, "acceptedAnswer": { "@type": "Answer", "text": "Elles sont analysées en comparant leur fréquence entre le groupe témoin et le groupe traité." } }, { "@type": "Question", "name": "Les groupes témoins aident-ils à identifier des facteurs de risque ?", "position": 13, "acceptedAnswer": { "@type": "Answer", "text": "Oui, ils permettent de comparer les facteurs de risque entre les groupes traité et témoin." } }, { "@type": "Question", "name": "Comment les facteurs de risque sont-ils évalués ?", "position": 14, "acceptedAnswer": { "@type": "Answer", "text": "Ils sont évalués par des questionnaires et des analyses statistiques dans les deux groupes." } } ] } ] }

Sources (10000 au total)

A Systematic Review and a Meta-analysis of Randomized Controlled Trials' Control Groups in Metastatic Hormone-Sensitive Prostate Cancer (mHSPC).

Determining the risk for progression or survival after standard androgen deprivation treatment (ADT) in metastatic hormone-sensitive prostate cancer (mHSPC) is essential for stratifying patients accor... Studies reporting time-dependent outcomes (progression or death) after standard ADT treatment of mHSPC were searched in MEDLINE, CANCERLIT, the Cochrane Controlled Trials Register, and the Cochrane Li...

Effect of concurrent training in unilateral transtibial amputees using Paralympic athletes as a control group.

Transtibial Amputation (TA) predisposes to a sedentary lifestyle.... To evaluate the efficiency of a short-term (8-week) Concurrent Training (CT) program in Unilateral Transtibial Amputees (UTA) and to compare it with the physical condition of a group of Paralympic ath... This was a longitudinal, prospective and controlled trial study.... Thirty-four male subjects with UTA and using prostheses for six months or more were selected for this study. They were divided into two groups: Group 1 (G1) ‒ 17 non-athlete and untrained UTA and Grou... Patients were retested by the same methods after CT. The two most important central dependent variables (maximal oxygen uptake and muscular strength) increased by 22% and knee extensor and flexor stre... After eight weeks of CT, there was an improvement in general functional condition, muscle strength, and cardiorespiratory performance improving protection against chronic diseases and quality of life....

Reactions to being allocated to a waiting list control group in a digital alcohol intervention trial.

To study reactions of control group participants allocated to two different presentations of basic health information in a digital alcohol intervention trial.... Control participants were randomised to wait with one of two different presentations of basic health information. Multiple choice questions and free-text comments assessed reactions, four months post ... Of 1066 control group participants, 572 (54%) responded to the questionnaire. Contrasting two different presentations of basic health information revealed no statistically significant differences. Res... Being made to wait may invite negative research participation effects.... Comparator guidance should be updated to reflect the potentially negative consequences which are under researched....

Use of Placebo and Nonoperative Control Groups in Surgical Trials: A Systematic Review and Meta-analysis.

Nonspecific effects, particularly placebo effects, are thought to contribute significantly to the observed effect in surgical trials.... To estimate the proportion of the observed effect of surgical treatment that is due to nonspecific effects (including the placebo effect).... Published Cochrane reviews and updated, extended search of MEDLINE, Embase, and CENTRAL until March 2019.... Published randomized placebo-controlled surgical trials and trials comparing the effect of the same surgical interventions with nonoperative controls (ie, no treatment, usual care, or exercise program... Pairs of authors independently screened the search results, assessed full texts to identify eligible studies and the risk of bias of included studies, and extracted data. The proportion of all nonspec... Between- and within-group effect sizes expressed as Hedges g.... In this review, 100 trials were included comprising data from 62 trials with placebo controls (3 also included nonoperative controls), and 38 trials with nonoperative controls (32 interventions; 10 69... In this review, the change in health state after surgery was composed largely of nonspecific effects, but no evidence supported a large placebo effect. Placebo-controlled surgical trials may be redund...

Control Groups in RCTs Supporting Approval of Drugs for Systemic Rheumatic Diseases, 2012-2022.

Randomized clinical trials (RCTs) testing innovative drugs must strive to use optimal control groups to reflect the best available treatments. A comprehensive evaluation of the quality of control grou... To examine the proportion of pivotal RCTs that used optimal control groups among RCTs supporting newly approved SRD drugs in the US over the past decade.... In this study, individual RCTs supporting SRD new drug approvals by the FDA between January 2012 and October 2022 were analyzed for design, study duration, control group, and primary end point. The qu... The primary measure was the proportion of RCTs using optimal control groups. Differences in response rate between investigating and control groups and the response rate of placebo control groups were ... Between January 2012 and October 2022, the FDA approved 44 SRD drugs, involving 65 pivotal RCTs. Overall, 16 RCTs used optimal control groups. In 55 trials, no active groups were used, and more than 8... These findings suggest that the quality of control groups in RCTs leading to SRD drug approval needs improvement and that despite challenges in translating scientific theories to clinical scenarios, i...

Internet-based self-help intervention for procrastination: randomized control group trial protocol.

Procrastination or "postponing until later" is a common phenomenon defined as the intentional delay in partaking in and finishing important activities despite negative outcomes potentially outweighing... This study explored the efficacy of an online-based self-help intervention in the context of voluntary procrastination among undergraduate psychology students. The study design is a randomized control... This randomized controlled trial will provide data on the effectiveness of online interventions for adult procrastination. If deemed effective, this low-cost, high-coverage internet-based intervention... Chinese Clinical Trial Registry. https://www.chictr.org.cn/showproj.aspx?proj=171246 ....

Arthroscopic rotator cuff repair in fibromyalgia patients had comparable outcomes to a matched control group.

Although fibromyalgia is associated with poor outcomes following orthopedic surgeries, several studies show some benefit from surgical intervention and nevertheless recommend operative treatment when ... All patients with a confirmed diagnosis of fibromyalgia who underwent ARCR in one institution between 2010 and 2021 were included. Data retrieved from medical records included demographics, characteri... There were no significant differences in demographics, cuff tear and surgical procedure characteristics, and preoperative scores between the fibromyalgia and control groups. The fibromyalgia patients'... Fibromyalgia patients with rotator cuff tears who undergo ARCR do not have inferior patient-reported outcomes compared with non-fibromyalgia controls. Fibromyalgia should not be a considered a contrai... III....