Titre : Régions d'ancrage à la matrice nucléaire

Régions d'ancrage à la matrice nucléaire : Questions médicales fréquentes

Termes MeSH sélectionnés :

Network Meta-Analysis
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MAR dans le génome ?\nQuels tests sont utilisés pour étudier les MAR ?\nLes MAR sont-elles visibles par microscopie ?\nPeut-on détecter des mutations dans les MAR ?\nLes MAR sont-elles associées à des maladies ?", "url": "https://questionsmedicales.fr/mesh/D045170?mesh_terms=Network+Meta-Analysis&page=2#section-diagnostic" }, { "@type": "MedicalWebPage", "name": "Symptômes", "headline": "Symptômes sur Régions d'ancrage à la matrice nucléaire", "description": "Quels symptômes sont liés aux anomalies des MAR ?\nLes MAR affectent-elles l'expression génique ?\nY a-t-il des symptômes associés aux cancers liés aux MAR ?\nLes MAR influencent-elles le développement embryonnaire ?\nLes anomalies des MAR peuvent-elles causer des troubles ?", "url": "https://questionsmedicales.fr/mesh/D045170?mesh_terms=Network+Meta-Analysis&page=2#section-symptômes" }, { "@type": "MedicalWebPage", "name": "Prévention", "headline": "Prévention sur Régions d'ancrage à la matrice nucléaire", "description": "Peut-on prévenir les anomalies des MAR ?\nY a-t-il des tests de dépistage pour les anomalies des MAR ?\nComment réduire le risque de cancers liés aux MAR ?\nL'alimentation influence-t-elle les MAR ?\nLes examens médicaux réguliers aident-ils ?", "url": "https://questionsmedicales.fr/mesh/D045170?mesh_terms=Network+Meta-Analysis&page=2#section-prévention" }, { "@type": "MedicalWebPage", "name": "Traitements", "headline": "Traitements sur Régions d'ancrage à la matrice nucléaire", "description": "Y a-t-il des traitements ciblant les MAR ?\nComment les thérapies géniques affectent-elles les MAR ?\nLes traitements du cancer affectent-ils les MAR ?\nPeut-on utiliser des médicaments pour moduler les MAR ?\nLes interventions chirurgicales peuvent-elles affecter les MAR ?", "url": "https://questionsmedicales.fr/mesh/D045170?mesh_terms=Network+Meta-Analysis&page=2#section-traitements" }, { "@type": "MedicalWebPage", "name": "Complications", "headline": "Complications sur Régions d'ancrage à la matrice nucléaire", "description": "Quelles complications peuvent survenir avec des anomalies des MAR ?\nLes anomalies des MAR peuvent-elles entraîner des maladies chroniques ?\nY a-t-il des complications liées aux traitements des MAR ?\nLes complications sont-elles réversibles ?\nLes anomalies des MAR affectent-elles la fertilité ?", "url": "https://questionsmedicales.fr/mesh/D045170?mesh_terms=Network+Meta-Analysis&page=2#section-complications" }, { "@type": "MedicalWebPage", "name": "Facteurs de risque", "headline": "Facteurs de risque sur Régions d'ancrage à la matrice nucléaire", "description": "Quels sont les facteurs de risque pour les anomalies des MAR ?\nL'âge influence-t-il les anomalies des MAR ?\nLe mode de vie affecte-t-il les MAR ?\nLes antécédents familiaux jouent-ils un rôle ?\nLes agents environnementaux influencent-ils les MAR ?", "url": "https://questionsmedicales.fr/mesh/D045170?mesh_terms=Network+Meta-Analysis&page=2#section-facteurs de risque" } ] }, { "@type": "FAQPage", "mainEntity": [ { "@type": "Question", "name": "Comment identifier les MAR dans le génome ?", "position": 1, "acceptedAnswer": { "@type": "Answer", "text": "Les MAR peuvent être identifiées par des techniques de séquençage et d'analyse bioinformatique." } }, { "@type": "Question", "name": "Quels tests sont utilisés pour étudier les MAR ?", "position": 2, "acceptedAnswer": { "@type": "Answer", "text": "Des tests comme la PCR et l'hybridation in situ sont couramment utilisés." } }, { "@type": "Question", "name": "Les MAR sont-elles visibles par microscopie ?", "position": 3, "acceptedAnswer": { "@type": "Answer", "text": "Non, les MAR ne sont pas directement visibles, mais leur effet sur la structure peut l'être." } }, { "@type": "Question", "name": "Peut-on détecter des mutations dans les MAR ?", "position": 4, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des mutations dans les MAR peuvent être détectées par séquençage ciblé." } }, { "@type": "Question", "name": "Les MAR sont-elles associées à des maladies ?", "position": 5, "acceptedAnswer": { "@type": "Answer", "text": "Certaines MAR peuvent être liées à des maladies génétiques ou à des cancers." } }, { "@type": "Question", "name": "Quels symptômes sont liés aux anomalies des MAR ?", "position": 6, "acceptedAnswer": { "@type": "Answer", "text": "Les anomalies des MAR peuvent entraîner des dysfonctionnements cellulaires, mais pas de symptômes spécifiques." } }, { "@type": "Question", "name": "Les MAR affectent-elles l'expression génique ?", "position": 7, "acceptedAnswer": { "@type": "Answer", "text": "Oui, les MAR jouent un rôle crucial dans la régulation de l'expression génique." } }, { "@type": "Question", "name": "Y a-t-il des symptômes associés aux cancers liés aux MAR ?", "position": 8, "acceptedAnswer": { "@type": "Answer", "text": "Les symptômes dépendent du type de cancer, mais peuvent inclure fatigue, douleur, et perte de poids." } }, { "@type": "Question", "name": "Les MAR influencent-elles le développement embryonnaire ?", "position": 9, "acceptedAnswer": { "@type": "Answer", "text": "Oui, les MAR sont impliquées dans la régulation des gènes essentiels au développement embryonnaire." } }, { "@type": "Question", "name": "Les anomalies des MAR peuvent-elles causer des troubles ?", "position": 10, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des anomalies peuvent contribuer à des troubles du développement ou des cancers." } }, { "@type": "Question", "name": "Peut-on prévenir les anomalies des MAR ?", "position": 11, "acceptedAnswer": { "@type": "Answer", "text": "La prévention est difficile, mais un mode de vie sain peut réduire les risques de maladies associées." } }, { "@type": "Question", "name": "Y a-t-il des tests de dépistage pour les anomalies des MAR ?", "position": 12, "acceptedAnswer": { "@type": "Answer", "text": "Actuellement, il n'existe pas de tests de dépistage spécifiques pour les anomalies des MAR." } }, { "@type": "Question", "name": "Comment réduire le risque de cancers liés aux MAR ?", "position": 13, "acceptedAnswer": { "@type": "Answer", "text": "Éviter les facteurs de risque connus comme le tabagisme et l'exposition à des agents cancérigènes." } }, { "@type": "Question", "name": "L'alimentation influence-t-elle les MAR ?", "position": 14, "acceptedAnswer": { "@type": "Answer", "text": "Une alimentation équilibrée peut influencer l'expression génique, y compris celle des MAR." } }, { "@type": "Question", "name": "Les examens médicaux réguliers aident-ils ?", "position": 15, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des examens réguliers peuvent aider à détecter précocement des maladies associées." } }, { "@type": "Question", "name": "Y a-t-il des traitements ciblant les MAR ?", "position": 16, "acceptedAnswer": { "@type": "Answer", "text": "Actuellement, il n'existe pas de traitements spécifiques ciblant les MAR." } }, { "@type": "Question", "name": "Comment les thérapies géniques affectent-elles les MAR ?", "position": 17, "acceptedAnswer": { "@type": "Answer", "text": "Les thérapies géniques peuvent modifier l'expression des gènes associés aux MAR." } }, { "@type": "Question", "name": "Les traitements du cancer affectent-ils les MAR ?", "position": 18, "acceptedAnswer": { "@type": "Answer", "text": "Oui, certains traitements du cancer peuvent influencer l'activité des MAR." } }, { "@type": "Question", "name": "Peut-on utiliser des médicaments pour moduler les MAR ?", "position": 19, "acceptedAnswer": { "@type": "Answer", "text": "Des recherches sont en cours pour développer des médicaments modulant l'activité des MAR." } }, { "@type": "Question", "name": "Les interventions chirurgicales peuvent-elles affecter les MAR ?", "position": 20, "acceptedAnswer": { "@type": "Answer", "text": "Indirectement, en modifiant l'environnement cellulaire, mais pas directement les MAR." } }, { "@type": "Question", "name": "Quelles complications peuvent survenir avec des anomalies des MAR ?", "position": 21, "acceptedAnswer": { "@type": "Answer", "text": "Les complications incluent des troubles du développement et un risque accru de cancers." } }, { "@type": "Question", "name": "Les anomalies des MAR peuvent-elles entraîner des maladies chroniques ?", "position": 22, "acceptedAnswer": { "@type": "Answer", "text": "Oui, certaines anomalies peuvent contribuer à des maladies chroniques comme le cancer." } }, { "@type": "Question", "name": "Y a-t-il des complications liées aux traitements des MAR ?", "position": 23, "acceptedAnswer": { "@type": "Answer", "text": "Les traitements peuvent avoir des effets secondaires, mais pas spécifiquement liés aux MAR." } }, { "@type": "Question", "name": "Les complications sont-elles réversibles ?", "position": 24, "acceptedAnswer": { "@type": "Answer", "text": "Certaines complications peuvent être gérées, mais d'autres peuvent être permanentes." } }, { "@type": "Question", "name": "Les anomalies des MAR affectent-elles la fertilité ?", "position": 25, "acceptedAnswer": { "@type": "Answer", "text": "Certaines anomalies peuvent influencer la fertilité, mais cela dépend du contexte génétique." } }, { "@type": "Question", "name": "Quels sont les facteurs de risque pour les anomalies des MAR ?", "position": 26, "acceptedAnswer": { "@type": "Answer", "text": "Les facteurs incluent des prédispositions génétiques et des expositions environnementales." } }, { "@type": "Question", "name": "L'âge influence-t-il les anomalies des MAR ?", "position": 27, "acceptedAnswer": { "@type": "Answer", "text": "Oui, l'âge avancé peut augmenter le risque de mutations génétiques, y compris dans les MAR." } }, { "@type": "Question", "name": "Le mode de vie affecte-t-il les MAR ?", "position": 28, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des habitudes comme le tabagisme et l'alimentation peuvent influencer les MAR." } }, { "@type": "Question", "name": "Les antécédents familiaux jouent-ils un rôle ?", "position": 29, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des antécédents familiaux de maladies génétiques peuvent augmenter le risque d'anomalies." } }, { "@type": "Question", "name": "Les agents environnementaux influencent-ils les MAR ?", "position": 30, "acceptedAnswer": { "@type": "Answer", "text": "Oui, l'exposition à des agents cancérigènes peut affecter l'intégrité des MAR." } } ] } ] }

Sources (10000 au total)

Network Meta-analysis of Different Treatments for Vestibular Migraine.

Although one of the major presentations of vestibular migraine is dizziness with/without unsteady gait, it is still classified as one of the migraine categories. However, in contrast to ordinary migra... The objective of this current network meta-analysis (NMA) was to compare the efficacy and acceptability of individual treatment strategies in patients with vestibular migraine.... The PubMed, Embase, ScienceDirect, ProQuest, Web of Science, ClinicalKey, Cochrane Central, and ClinicalTrials.gov databases were systematically searched for randomized controlled trials (RCTs), with ... Seven randomized controlled trials (N = 828, mean age 37.6 years, 78.4% female) and seven active regimens were included. We determined that only valproic acid (standardized mean difference [SMD] -1.61... The current study provides evidence that only valproic acid, propranolol, and venlafaxine might be associated with beneficial efficacy in vestibular migraine treatment.... CRD42023388343....

Preventive Medications in Pediatric Migraine: A Network Meta-Analysis.

Pediatric migraine substantially impacts quality of life and academic performance among children and adolescents. Understanding the efficacy and safety of pharmacological interventions for migraine pr... To conduct a comprehensive network meta-analysis to evaluate the efficacy and safety associated with pharmacological treatments for pediatric migraine prophylaxis among pediatric patients with a migra... PubMed, Embase, and SCOPUS were searched for publications up to September 2023. Search terms and indexing were chosen to encompass relevant studies, focusing on randomized clinical trials in pediatric... Inclusion criteria targeted randomized clinical trials involving pediatric patients with migraine. Studies were selected based on their examination of oral pharmacological interventions. The search yi... Data extraction adhered to Preferred Reporting Items for Systematic Reviews and Meta-Analyses reporting guidelines. Five investigators independently extracted study data into a spreadsheet in duplicat... The primary outcome was migraine frequency (number of attacks per month). Secondary outcomes included a 50% or greater responder rate, headache duration, headache intensity, and disability (assessed b... The analysis incorporated 45 trials with 3771 participants. Compared with placebo, pregabalin (ratio of means [RoM], 0.38; 95% CI, 0.18-0.79) and topiramate with vitamin D3 (RoM, 0.44; 95% CI, 0.30-0.... In this network meta-analysis of randomized clinical trials, topiramate and pregabalin were associated with reduction in headache frequency and intensity. Although there were also other drugs that sho...

Efficacy of Laser in Hair Removal: A Network Meta-analysis.

Laser hair removal is an increasingly prevalent trend of cosmetic procedures. The purpose of this study was to assess the effectiveness of hair reduction among several types of laser interventions.... The selected studies searched in PubMed and EMBASE were assessed for quality of evidence, and extracted data on absolute hair count and hair reduction rate. Qualitative data were synthesized using sta... A total of 13 randomized controlled trials (RCTs) (... Eliminating unwanted hair with lasers or intense pulsed light is safe and effective; however, which type of intervention is more beneficial in the long-term process should be studied with a longer fol...

A network meta-analysis of arthroscopic rotator cuff repair.

Rotator cuff tear is a common shoulder injury that often leads to serious limitations in daily life. Herein, a network Meta-analysis using frequency theory was performed to evaluate the clinical outco... PubMed, EMbase, The Cochrane Library, and Web of Science were searched for randomized controlled trials and cohort studies comparing rotator cuff repair techniques published from inception to May 2022... A total of 51 articles were finally included, including 27 randomized controlled trials and 24 cohort studies. Results from the network Meta-analysis showed that: (1) In terms of the American Shoulder... Based on the results of network Meta-analysis and surface under the cumulative ranking, platelet-rich plasma therapy, bone marrow stimulation, and double-row repair have good overall rehabilitation ef...

Treatment of children with infantile spasms: A network meta-analysis.

We performed a systematic review and network meta-analysis (NMA) to obtain comparative effectiveness estimates and rankings of non-surgical interventions used to treat infantile spasms.... All randomized controlled trials (RCTs) including children 2 months to 3 years of age with infantile spasms (with hypsarrhythmia or hypsarrhythmia variants on electroencephalography) receiving appropr... Twenty-two RCTs comparing first-line treatments for infantile spasms were reviewed; of these, 17 were included in the NMA. Both frequentist and Bayesian network rankings for electroclinical remission ... Treatments including ACTH and high dose prednisolone are more effective in achieving electroclinical and clinical remissions for infantile spasms.... Adrenocorticotropic hormone and high dose prednisolone are more effective than other medications for infantile spasms. Symptomatic etiology decreases the likelihood of remission even after adjusting f...

Comparison of interventions for Barrett's esophagus: A network meta-analysis.

Barrett's esophagus (BE) is a precancerous condition that has the potential to develop into esophageal cancer (EC). Currently, there is a wide range of management options available for individuals at ... Data extracted from eligible randomized controlled trials were utilized in a Bayesian network meta-analysis to examine the relative effectiveness of BE's treatment regimens and determine their ranking... We identified twenty-three RCT studies with a total of 1675 participants, and ten different interventions. Regarding complete ablation of non-dysplastic BE, the comparative effectiveness ranking indic... Endoscopic surveillance alone or PPI/H2RA alone may not be sufficient for managing BE, even in cases of non-dysplastic BE. However, APC has shown excellent efficacy in treating non-dysplastic BE. For ...

Treatment of diabetic kidney disease. A network meta-analysis.

Diabetic kidney disease (DKD) is a health burden of rising importance. Slowing progression to end stage kidney disease is the main goal of drug treatment. The aim of this analysis is to compare drug t... We searched Medline, CENTRAL and clinicaltrials.gov for randomized, controlled studies including adults with DKD treated with the following drugs of interest: single angiotensin-converting-enzyme-inhi... Of initial 3489 publications, 38 clinical trials were found eligible, in total including 42346 patients. Concerning the primary endpoints overall mortality and end stage kidney disease, SGLT2i on top ... As the only drug class, SGLT2i showed in our analysis beneficial effects on top of ACEi/ARB treatment regarding mortality and end stage kidney disease and by that reconfirmed its position as treatment...

Pharmaceutical Therapies for the Treatment of Obesity: A Network Meta-analysis.

Despite the introduction of various pharmaceutical therapies for treating obesity, selecting the optimal treatment remains challenging for both patients and physicians. Therefore, in this network meta... International databases, including PubMed, Web of Science, Scopus, Cochrane Library, and Embase, were searched for studies published from database inception to April 2023. The consistency assumption w... Of 9519 retrieved references, 96 randomized controlled trials, including 68 with both men and women, 23 with women only, and 5 with men only, met the eligibility criteria for this study. There were 4 ... According to the results of this NMA, semaglutide seems to be an effective treatment option for both men and women, whereas beloranib appears to be particularly effective for women with obesity and ov...

Model selection for component network meta-analysis in connected and disconnected networks: a simulation study.

Network meta-analysis (NMA) allows estimating and ranking the effects of several interventions for a clinical condition. Component network meta-analysis (CNMA) is an extension of NMA which considers t... We evaluate a forward model selection strategy for component network meta-analysis to relax the additivity assumption that can be used in connected or disconnected networks. In addition, we describe a... CNMA models provide good performance for connected networks and can be an alternative to standard NMA if additivity holds. For disconnected networks, we recommend to use additive CNMA only if strong c... CNMA methods are feasible for connected networks but questionable for disconnected networks....