questionsmedicales.fr
Enzymes et coenzymes
Enzymes
Recombinases
Holliday junction resolvases
Holliday junction resolvases : Questions médicales fréquentes
Importance clinique
2
Cancer
Intégrité génétique
Thérapies ciblées
Inhibiteurs enzymatiques
Mécanisme d'action
2
Clivage de l'ADN
Mécanisme enzymatique
Cofacteurs enzymatiques
Ions métalliques
Recherche et développement
2
Recherche biomédicale
Maladies génétiques
Modèles animaux
Études murines
Interactions avec d'autres protéines
2
Protéines de réparation
Interactions protéiques
Précision de la réparation
Complexes protéiques
Fonction des Holliday junction resolvases
2
Enzymes
Réparation de l'ADN
Recombinaison génétique
Holliday junction
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Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale
Validation scientifique effectuée le 15/02/2026
Contenu vérifié selon les dernières recommandations médicales
8 publications dans cette catégorie
Affiliations :
Micron School of Materials Science and Engineering, Boise State University Boise ID 83725 USA lanli@boisestate.edu.
Department of Electrical and Computer Engineering, Boise State University Boise ID 83725 USA.
8 publications dans cette catégorie
Affiliations :
Micron School of Materials Science and Engineering, Boise State University Boise ID 83725 USA lanli@boisestate.edu.
Department of Electrical and Computer Engineering, Boise State University Boise ID 83725 USA.
6 publications dans cette catégorie
5 publications dans cette catégorie
Publications dans "Holliday junction resolvases" :
4 publications dans cette catégorie
Affiliations :
College of Chemistry, Fuzhou University, Fuzhou, 350108, China. Electronic address: Zhonghui.lin@fzu.edu.cn.
Publications dans "Holliday junction resolvases" :
4 publications dans cette catégorie
Affiliations :
Micron School of Materials Science and Engineering, Boise State University Boise ID 83725 USA lanli@boisestate.edu.
Center for Advanced Energy Studies Idaho Falls ID 83401 USA.
Publications dans "Holliday junction resolvases" :
4 publications dans cette catégorie
Publications dans "Holliday junction resolvases" :
4 publications dans cette catégorie
Affiliations :
Department of Microbiology & Immunology, College of Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.
Publications dans "Holliday junction resolvases" :
4 publications dans cette catégorie
Affiliations :
Department of Microbiology & Immunology, College of Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.
Publications dans "Holliday junction resolvases" :
4 publications dans cette catégorie
Affiliations :
Department of Microbiology & Immunology, College of Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.
Publications dans "Holliday junction resolvases" :
3 publications dans cette catégorie
Affiliations :
Molecular Biology and Biochemistry Department, Wesleyan University, Middletown, CT 06459, USA.
Molecular Biophysics Program, Wesleyan University, Middletown, CT 06459, USA.
Publications dans "Holliday junction resolvases" :
3 publications dans cette catégorie
Affiliations :
The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK. Electronic address: stephen.west@crick.ac.uk.
Publications dans "Holliday junction resolvases" :
3 publications dans cette catégorie
Publications dans "Holliday junction resolvases" :
3 publications dans cette catégorie
Affiliations :
SETA BioMedicals, LLC, 2014 Silver Court East, Urbana, Illinois 61801, United States.
Publications dans "Holliday junction resolvases" :
3 publications dans cette catégorie
Publications dans "Holliday junction resolvases" :
3 publications dans cette catégorie
Affiliations :
Institute of Biophysics of the Czech Academy of Sciences, Královopolská 135, 612 65, Brno, Czech Republic.
Regional Centre of Advanced Technologies and Materials, Czech Advanced Technology and Research Institute (CATRIN), Palacky University Olomouc, Slechtitelu 241/27,783 71, Olomouc, Czech Republic.
Publications dans "Holliday junction resolvases" :
3 publications dans cette catégorie
Affiliations :
Institute of Biophysics of the Czech Academy of Sciences, Královopolská 135, 612 65, Brno, Czech Republic.
Regional Centre of Advanced Technologies and Materials, Czech Advanced Technology and Research Institute (CATRIN), Palacky University Olomouc, Slechtitelu 241/27,783 71, Olomouc, Czech Republic.
Publications dans "Holliday junction resolvases" :
3 publications dans cette catégorie
Affiliations :
Micron School of Materials Science & Engineering, Boise State University, Boise, Idaho 83725, United States.
Publications dans "Holliday junction resolvases" :
3 publications dans cette catégorie
Affiliations :
State Key Laboratory of Pharmaceutical Biotechnology, Department of Cardiology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School and MOE Key Laboratory of Model Animal for Disease Study, Model Animal Research Center, Nanjing University, Nanjing, China.
Publications dans "Holliday junction resolvases" :
3 publications dans cette catégorie
Affiliations :
State Key Laboratory of Pharmaceutical Biotechnology, Department of Cardiology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School and MOE Key Laboratory of Model Animal for Disease Study, Model Animal Research Center, Nanjing University, Nanjing, China. Electronic address: zhongzhouyang@nju.edu.cn.
Publications dans "Holliday junction resolvases" :
Cyanobacteria, which have a photoautotrophic lifestyle, are threatened by ultraviolet solar rays and the reactive oxygen species generated during photosynthesis. They can adapt to environmental condit...
Holliday junction resolution is a crucial process in homologous recombination and DNA double-strand break repair. Complete Holliday junction resolution requires two stepwise incisions across the cente...
A biofilm lifestyle is critical for bacterial pathogens to colonize and protect themselves from host immunity and antimicrobial chemicals in plants and animals. The formation and regulation mechanisms...
The incidence of multiple primary malignancies (MPMs) involving lung cancer has increased in recent decades. There is an urgent need to clarify the genetic profile of such patients and explore more ef...
Peripheral blood samples from MPMs involving lung cancer patients were assessed by whole exome sequencing (WES) and the identified variants were referenced for pathogenicity using the public available...
Germline exomes of 71 patients diagnosed with MPMs involving lung cancer were sequenced. Pathway enrichment analysis shows that homologous recombination repair (HRR) pathway has the strongest correlat...
This is the first study to map the profile of germline mutations in patients with MPMs involving lung cancer. This study may shed light on early prevention and novel targeted therapies for MPMs involv...
In eubacteria, Holliday junction (HJ) resolvases (HJRs) are crucial for faithful segregation of newly replicated chromosomes, homologous recombination and repair of stalled/collapsed DNA replication f...
The insertion sequence IS...
Cells are continually exposed to a multitude of internal and external stressors, which give rise to various types of DNA damage. To protect the integrity of their genetic material, cells are equipped ...
Holliday junctions are key intermediate DNA structures during genetic recombination. One of the first Holliday junction-processing protein complexes to be discovered was the well conserved RuvAB branc...
Chromosomal linkages formed through crossover recombination are essential for accurate segregation of homologous chromosomes during meiosis...
Holliday 4-way junctions are key to important biological DNA processes (insertion, recombination, and repair) and are dynamic structures that adopt either open or closed conformations, the open confor...