questionsmedicales.fr
Composés polycycliques
Composés macrocycliques
Lactames macrocycliques
Lactames macrocycliques : Questions médicales fréquentes
Termes MeSH sélectionnés :
Diagnostic
5
Infections bactériennes
Cultures bactériennes
Antibiotiques
Tests de sensibilité
Efficacité
Cultures positives
Imagerie médicale
Infections profondes
Symptômes
5
Symptômes
Infections bactériennes
Effets secondaires
Eruptions cutanées
Réaction allergique
Démangeaisons
Prévention
5
Prophylaxie
Infections post-chirurgicales
Vaccinations
Infections bactériennes
Résistance aux antibiotiques
Prescriptions médicales
Traitements
5
Administration
Voie intraveineuse
Mécanisme d'action
Paroi cellulaire
Durée du traitement
Infections
Effets secondaires
Ajustement du traitement
Complications
5
Complications
Réactions allergiques
Surinfection
Évaluation médicale
Troubles rénaux
Surveillance
Réaction sévère
Urgence médicale
Interactions médicamenteuses
Médecin
Facteurs de risque
5
Facteurs de risque
Immunodépression
Antécédents médicaux
Allergies
Personnes âgées
Système immunitaire
Voyages
Agents pathogènes
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"name": "Comment diagnostiquer une infection bactérienne ?",
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"text": "Le diagnostic repose sur des cultures bactériennes et des tests de sensibilité."
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{
"@type": "Question",
"name": "Quels tests sont utilisés pour les lactames macrocycliques ?",
"position": 2,
"acceptedAnswer": {
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"text": "Des tests de sensibilité aux antibiotiques sont effectués pour évaluer l'efficacité."
}
},
{
"@type": "Question",
"name": "Quels symptômes indiquent une infection nécessitant des lactames ?",
"position": 3,
"acceptedAnswer": {
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"name": "Comment évaluer l'efficacité des lactames macrocycliques ?",
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"@type": "Question",
"name": "Quels sont les symptômes d'une infection bactérienne ?",
"position": 6,
"acceptedAnswer": {
"@type": "Answer",
"text": "Fièvre, frissons, douleur, rougeur et gonflement au site d'infection sont fréquents."
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"@type": "Question",
"name": "Les lactames provoquent-ils des effets secondaires ?",
"position": 7,
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"text": "Oui, des effets secondaires comme des éruptions cutanées ou des troubles gastro-intestinaux peuvent survenir."
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{
"@type": "Question",
"name": "Comment reconnaître une réaction allergique ?",
"position": 8,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des démangeaisons, un gonflement ou des difficultés respiratoires peuvent indiquer une allergie."
}
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{
"@type": "Question",
"name": "Quels signes d'infection nécessitent une attention médicale ?",
"position": 9,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une fièvre élevée persistante ou des douleurs intenses doivent être évaluées par un médecin."
}
},
{
"@type": "Question",
"name": "Les lactames macrocycliques affectent-ils le système digestif ?",
"position": 10,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, ils peuvent causer des nausées, vomissements ou diarrhées chez certains patients."
}
},
{
"@type": "Question",
"name": "Comment prévenir les infections bactériennes ?",
"position": 11,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une bonne hygiène, des vaccinations et un usage prudent des antibiotiques aident à prévenir."
}
},
{
"@type": "Question",
"name": "Les lactames macrocycliques sont-ils utilisés en prophylaxie ?",
"position": 12,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, ils peuvent être utilisés en prophylaxie pour prévenir des infections post-chirurgicales."
}
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{
"@type": "Question",
"name": "Quelles mesures d'hygiène sont recommandées ?",
"position": 13,
"acceptedAnswer": {
"@type": "Answer",
"text": "Se laver les mains régulièrement et éviter le contact avec des personnes malades sont essentiels."
}
},
{
"@type": "Question",
"name": "Les vaccinations aident-elles contre les infections ?",
"position": 14,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, certaines vaccinations peuvent réduire le risque d'infections bactériennes spécifiques."
}
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{
"@type": "Question",
"name": "Comment éviter la résistance aux antibiotiques ?",
"position": 15,
"acceptedAnswer": {
"@type": "Answer",
"text": "Utiliser les antibiotiques uniquement lorsque nécessaire et suivre les prescriptions médicales."
}
},
{
"@type": "Question",
"name": "Comment les lactames macrocycliques sont-ils administrés ?",
"position": 16,
"acceptedAnswer": {
"@type": "Answer",
"text": "Ils peuvent être administrés par voie intraveineuse ou orale, selon l'infection."
}
},
{
"@type": "Question",
"name": "Quel est le mécanisme d'action des lactames ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "Ils inhibent la synthèse de la paroi cellulaire bactérienne, entraînant la mort des bactéries."
}
},
{
"@type": "Question",
"name": "Combien de temps dure un traitement typique ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "La durée du traitement varie, mais elle est généralement de 7 à 14 jours selon l'infection."
}
},
{
"@type": "Question",
"name": "Quels antibiotiques sont des lactames macrocycliques ?",
"position": 19,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des exemples incluent la méropénème et l'imipénème, utilisés pour des infections graves."
}
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{
"@type": "Question",
"name": "Comment gérer les effets secondaires des lactames ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
"text": "Il est important de signaler tout effet indésirable au médecin pour ajuster le traitement."
}
},
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"@type": "Question",
"name": "Quelles complications peuvent survenir avec les lactames ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des réactions allergiques graves ou des infections secondaires peuvent survenir."
}
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{
"@type": "Question",
"name": "Comment gérer une surinfection ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une évaluation médicale est nécessaire pour ajuster le traitement et cibler la nouvelle infection."
}
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{
"@type": "Question",
"name": "Les lactames peuvent-ils causer des troubles rénaux ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, certains lactames peuvent affecter la fonction rénale, nécessitant une surveillance."
}
},
{
"@type": "Question",
"name": "Quels sont les signes d'une réaction sévère ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des symptômes comme des difficultés respiratoires ou un gonflement du visage nécessitent une urgence."
}
},
{
"@type": "Question",
"name": "Les lactames macrocycliques peuvent-ils interagir avec d'autres médicaments ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, ils peuvent interagir avec d'autres médicaments, il est donc important d'informer le médecin."
}
},
{
"@type": "Question",
"name": "Quels facteurs augmentent le risque d'infection ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "L'immunodépression, le diabète et les interventions chirurgicales augmentent le risque."
}
},
{
"@type": "Question",
"name": "Les antécédents d'allergies influencent-ils le traitement ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des antécédents d'allergies aux antibiotiques peuvent limiter les options de traitement."
}
},
{
"@type": "Question",
"name": "Le mode de vie affecte-t-il le risque d'infection ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, un mode de vie sédentaire et une mauvaise alimentation peuvent augmenter le risque."
}
},
{
"@type": "Question",
"name": "Les personnes âgées sont-elles plus à risque ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les personnes âgées ont un système immunitaire affaibli, les rendant plus vulnérables."
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"@type": "Question",
"name": "Les voyages augmentent-ils le risque d'infections ?",
"position": 30,
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"text": "Oui, les voyages peuvent exposer à des agents pathogènes inconnus, augmentant le risque d'infection."
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Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale
Validation scientifique effectuée le 15/04/2025
Contenu vérifié selon les dernières recommandations médicales
3 publications dans cette catégorie
Affiliations :
Department of Chemistry, The University of Texas at Austin, Austin, Texas 78712-1224, United States.
Publications dans "Lactames macrocycliques" :
3 publications dans cette catégorie
Affiliations :
College of Sciences, Center for Supramolecular Chemistry and Catalysis, Shanghai University, Shanghai, 200444, People's Republic of China. cjli@shu.edu.cn.
Tianjin Key Laboratory of Structure and Performance for Functional Molecules, College of Chemistry, Tianjin Normal University, Tianjin, 300387, People's Republic of China. cjli@shu.edu.cn.
Publications dans "Lactames macrocycliques" :
2 publications dans cette catégorie
Affiliations :
Department of Chemistry, University of York, Heslington York YO10 5DD UK William.unsworth@york.ac.uk.
Publications dans "Lactames macrocycliques" :
2 publications dans cette catégorie
Affiliations :
Department of Chemistry, University of York, Heslington York YO10 5DD UK William.unsworth@york.ac.uk.
Publications dans "Lactames macrocycliques" :
2 publications dans cette catégorie
Affiliations :
Department of Chemistry, University of York, Heslington York YO10 5DD UK William.unsworth@york.ac.uk.
Publications dans "Lactames macrocycliques" :
2 publications dans cette catégorie
Affiliations :
Department of Chemistry, Faculty of Science, Kuwait University, P.O. Box 5969, Safat 13060, Kuwait.
Publications dans "Lactames macrocycliques" :
2 publications dans cette catégorie
Affiliations :
Department of Chemistry, Faculty of Science, Kuwait University, P.O. Box 5969, Safat 13060, Kuwait.
Publications dans "Lactames macrocycliques" :
2 publications dans cette catégorie
Affiliations :
State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha 410082, People's Republic of China.
Publications dans "Lactames macrocycliques" :
2 publications dans cette catégorie
Affiliations :
State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha 410082, People's Republic of China.
Publications dans "Lactames macrocycliques" :
2 publications dans cette catégorie
Affiliations :
Tianjin Key Laboratory of Structure and Performance for Functional Molecules, College of Chemistry, Tianjin Normal University, Tianjin, 300387, People's Republic of China.
Publications dans "Lactames macrocycliques" :
2 publications dans cette catégorie
Affiliations :
Centro de Investigacións Cientı́ficas Avanzadas (CICA) and Departamento de Quı́mica, Universidade da Coruña, Campus da Zapateira-Rúa da Fraga 10, 15008 A Coruña, Spain.
Publications dans "Lactames macrocycliques" :
2 publications dans cette catégorie
Affiliations :
Centro de Investigacións Cientı́ficas Avanzadas (CICA) and Departamento de Quı́mica, Universidade da Coruña, Campus da Zapateira-Rúa da Fraga 10, 15008 A Coruña, Spain.
Publications dans "Lactames macrocycliques" :
1 publication dans cette catégorie
Affiliations :
Key Laboratory of Green Prevention and Control of Tropical Plant Diseases and Pests, Ministry of Education, College of Plant Protection, Hainan University, Haikou 570228, China.
Publications dans "Lactames macrocycliques" :
1 publication dans cette catégorie
Affiliations :
Key Laboratory of Green Prevention and Control of Tropical Plant Diseases and Pests, Ministry of Education, College of Plant Protection, Hainan University, Haikou 570228, China.
Publications dans "Lactames macrocycliques" :
1 publication dans cette catégorie
Affiliations :
Key Laboratory of Green Prevention and Control of Tropical Plant Diseases and Pests, Ministry of Education, College of Plant Protection, Hainan University, Haikou 570228, China.
Publications dans "Lactames macrocycliques" :
1 publication dans cette catégorie
Affiliations :
Key Laboratory of Green Prevention and Control of Tropical Plant Diseases and Pests, Ministry of Education, College of Plant Protection, Hainan University, Haikou 570228, China.
Publications dans "Lactames macrocycliques" :
1 publication dans cette catégorie
Affiliations :
Key Laboratory of Green Prevention and Control of Tropical Plant Diseases and Pests, Ministry of Education, College of Plant Protection, Hainan University, Haikou 570228, China.
Publications dans "Lactames macrocycliques" :
1 publication dans cette catégorie
Affiliations :
Key Laboratory of Green Prevention and Control of Tropical Plant Diseases and Pests, Ministry of Education, College of Plant Protection, Hainan University, Haikou 570228, China.
Publications dans "Lactames macrocycliques" :
1 publication dans cette catégorie
Affiliations :
Department of Chemistry, University of York, Heslington York YO10 5DD UK William.unsworth@york.ac.uk.
Publications dans "Lactames macrocycliques" :
1 publication dans cette catégorie
Affiliations :
Natural Products Research Institute, College of Pharmacy , Seoul National University , Seoul 08826 , Republic of Korea.
Publications dans "Lactames macrocycliques" :
Forensic clinicians work with some of the most vulnerable members of society. Despite this it is one of the few areas of front line, undifferentiated healthcare in the UK that does not come under the ...
The Orphan Regulation ((EC) No 141/2000) has successfully redirected private and public investment towards previously neglected areas through incentives, regulatory obligations and rewards. However, t...
Expenditure on OMPs in Wales was analysed between the 2014/15 and 2019/20 financial years using data on prescriptions dispensed in primary care, secondary care, and specialised commissioned services. ...
Overall spend on OMPs and all medicines increased from £32 m to £82 m, and from £1,030 m to £1,198 m, respectively, with the proportion of spend on OMPs more than doubling from 3.1% to 6.9% per annum....
Both the number of OMPs and the amount spent on OMPs in Wales has increased over time, possibly as a consequence of favourable licensing conditions, permissive health technology assessment policies an...
The main objective of this study was to explore the extent to which the incremental cost-effectiveness ratio (ICER), alongside other factors, predicts the final outcome of medicine price negotiation i...
Data were extracted from company dossiers submitted to the Italian Medicines Agency (AIFA) from October 2016 to January 2021 and AIFA's internal database. Beta-based regression analyses were used to t...
In our dataset of 48 pricing and reimbursement procedures, the ICER before negotiation was one of the variables with a major impact on the outcome of negotiation when ≥ 40,000€/QALY. As resulting from...
This study provides support on the influence of cost-effectiveness analysis on price negotiation in the Italian context, providing an estimate of the mean ICER of reimbursed medicines, calculated usin...
Home healthcare in the Italian health system has proven to be an essential factor in adequately responding to the health needs of an increasingly aging population. The opportunities offered by digitiz...
The goal of cancer screening guidelines is to inform health practitioners to practice evidence-based cancer prevention. Cancer screening aims to detect treatable precancerous lesions or early-stage di...
In Italy, the number of physicians decreased in recent years due to retirements not being replaced by young specialists. To address this shortage of medical personnel, proper planning is needed, takin...
A variety of incentives are used to stimulate recruitment to remote and rural locations. In this presentation, we share experiences at the University of Central Lancashire of forming partnerships with...
Qualitative structured interviews....
NHS organisations priorities were to find cost-effective and successful strategies to recruit and retain workers. Many had tried financial incentives, including 'golden handshakes' and 'golden handcuf...
This partnership approach has helped us develop MSc programmes that fit with the needs of their services and innovatively support their recruitment aims. We have also given voice to the needs of our l...
Direct treatment disutility (DTD) represents an individual's disutility associated with the inconvenience of taking medicine over a long period of time....
The main aim of this study was to elicit DTD values for taking a statin or a bisphosphonate for primary prevention. A secondary aim was to understand factors which influence DTD values....
A total of 879 respondents were included for analysis (514 for statins and 365 for bisphosphonates). The majority of respondents reported a disutility associated with medicine use. Mean DTD for statin...
Statins and bisphosphonates have a quantifiable DTD. The size of estimated disutilities suggest they are likely to be important for cost-effectiveness, particularly in individuals at low-risk when tre...
Food allergy (FA) is a growing issue worldwide. The United Kingdom and United States are high-income, industrialized countries with reported increases in FA prevalence over the past few decades. This ...
Medication-related harm (MRH) is an escalating global challenge especially among older adults. The period following hospital discharge carries high-risk for MRH due to medication discrepancies, limite...
Using a randomized control trial design, 682 older adults ≥ 65 years due to be discharged from hospital will be recruited from 4 sites. Participants will be randomized to an intervention arm (individu...
Univariate analysis will be done for baseline variables comparing the intervention and control arms. A multivariate logistic regression will be done incorporating these variables. Economic evaluation ...
This study will inform the use of an objective, validated RPT for MRH among older adults after hospital discharge, and provide a clinical, economic, and service evaluation of a specific medicines mana...