questionsmedicales.fr
Acides aminés, peptides et protéines
Protéines
Protéines et peptides de signalisation intracellulaire
Protein-Serine-Threonine Kinases
Mitogen-Activated Protein Kinases
Extracellular Signal-Regulated MAP Kinases
Mitogen-Activated Protein Kinase 3
Mitogen-Activated Protein Kinase 3 : Questions médicales fréquentes
Termes MeSH sélectionnés :
Diagnostic
5
Kinases
Signalisation cellulaire
Protéomique
Phosphorylation
Cancers
Maladies inflammatoires
Symptômes
5
Système immunitaire
Réponse immunitaire
Éruptions cutanées
Troubles métaboliques
Troubles neurologiques
Dysfonction
Stress cellulaire
Apoptose
Prévention
5
Mode de vie sain
Nutrition
Tabagisme
Graisses saturées
Traitements
5
Thérapie génique
Mutations
Médicaments
Inhibiteurs de MEK
Plantes médicinales
Signalisation
Complications
5
Complications
Inflammation chronique
Maladies auto-immunes
Anomalies
Cancer
Activation aberrante
Risques cardiovasculaires
Maladies cardiovasculaires
Vieillissement
Dysfonctionnements
Facteurs de risque
5
Âge
Signalisation cellulaire
Prédispositions génétiques
Mutations
Mode de vie sédentaire
Mauvaise alimentation
Infections virales
Perturbation
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"name": "Comment diagnostiquer une dysfonction de MAPK3 ?",
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"@type": "Question",
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"position": 6,
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"@type": "Question",
"name": "MAPK3 affecte-t-elle le système immunitaire ?",
"position": 7,
"acceptedAnswer": {
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{
"@type": "Question",
"name": "Quels signes cliniques sont associés à MAPK3 ?",
"position": 8,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des signes comme des éruptions cutanées ou des troubles métaboliques peuvent apparaître."
}
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{
"@type": "Question",
"name": "Y a-t-il des symptômes neurologiques liés à MAPK3 ?",
"position": 9,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des troubles neurologiques peuvent survenir en cas de dysfonction de MAPK3."
}
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{
"@type": "Question",
"name": "Comment la MAPK3 influence-t-elle le stress cellulaire ?",
"position": 10,
"acceptedAnswer": {
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"text": "Elle régule les réponses au stress, affectant la survie cellulaire et l'apoptose."
}
},
{
"@type": "Question",
"name": "Comment prévenir les dysfonctionnements de MAPK3 ?",
"position": 11,
"acceptedAnswer": {
"@type": "Answer",
"text": "Un mode de vie sain, incluant une bonne nutrition et de l'exercice, est recommandé."
}
},
{
"@type": "Question",
"name": "Y a-t-il des habitudes à éviter pour MAPK3 ?",
"position": 12,
"acceptedAnswer": {
"@type": "Answer",
"text": "Éviter le tabagisme et une alimentation riche en graisses saturées est conseillé."
}
},
{
"@type": "Question",
"name": "Le stress peut-il affecter MAPK3 ?",
"position": 13,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le stress chronique peut perturber la signalisation de MAPK3."
}
},
{
"@type": "Question",
"name": "Des exercices spécifiques aident-ils MAPK3 ?",
"position": 14,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des exercices réguliers peuvent améliorer la régulation de MAPK3."
}
},
{
"@type": "Question",
"name": "La gestion du poids influence-t-elle MAPK3 ?",
"position": 15,
"acceptedAnswer": {
"@type": "Answer",
"text": "Maintenir un poids santé peut aider à réguler l'activité de MAPK3."
}
},
{
"@type": "Question",
"name": "Quels traitements ciblent MAPK3 ?",
"position": 16,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des inhibiteurs spécifiques de MAPK3 sont en développement pour traiter certains cancers."
}
},
{
"@type": "Question",
"name": "La thérapie génique peut-elle corriger MAPK3 ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "La thérapie génique est une approche potentielle pour corriger des mutations de MAPK3."
}
},
{
"@type": "Question",
"name": "Quels médicaments affectent la voie MAPK3 ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des médicaments comme les inhibiteurs de MEK peuvent moduler l'activité de MAPK3."
}
},
{
"@type": "Question",
"name": "Y a-t-il des traitements naturels pour MAPK3 ?",
"position": 19,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines plantes médicinales peuvent influencer la signalisation de MAPK3."
}
},
{
"@type": "Question",
"name": "Comment la nutrition influence-t-elle MAPK3 ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une alimentation riche en antioxydants peut moduler l'activité de MAPK3."
}
},
{
"@type": "Question",
"name": "Quelles complications peuvent survenir avec une dysfonction de MAPK3 ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des complications comme le cancer, l'inflammation chronique et des troubles métaboliques peuvent survenir."
}
},
{
"@type": "Question",
"name": "MAPK3 est-elle liée à des maladies auto-immunes ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des anomalies dans MAPK3 peuvent contribuer à des maladies auto-immunes."
}
},
{
"@type": "Question",
"name": "Comment MAPK3 affecte-t-elle le cancer ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une activation aberrante de MAPK3 est souvent observée dans divers types de cancer."
}
},
{
"@type": "Question",
"name": "Y a-t-il des risques cardiovasculaires liés à MAPK3 ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des études suggèrent un lien entre MAPK3 et des maladies cardiovasculaires."
}
},
{
"@type": "Question",
"name": "MAPK3 peut-elle influencer le vieillissement ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des dysfonctionnements de MAPK3 sont associés à des processus de vieillissement prématuré."
}
},
{
"@type": "Question",
"name": "Quels facteurs de risque sont associés à MAPK3 ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des facteurs comme l'obésité, le tabagisme et le stress sont des risques connus."
}
},
{
"@type": "Question",
"name": "L'âge influence-t-il l'activité de MAPK3 ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'activité de MAPK3 peut diminuer avec l'âge, affectant la signalisation cellulaire."
}
},
{
"@type": "Question",
"name": "Y a-t-il des prédispositions génétiques pour MAPK3 ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines mutations génétiques peuvent prédisposer à des dysfonctionnements de MAPK3."
}
},
{
"@type": "Question",
"name": "Le mode de vie influence-t-il MAPK3 ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, un mode de vie sédentaire et une mauvaise alimentation augmentent les risques."
}
},
{
"@type": "Question",
"name": "Des infections peuvent-elles affecter MAPK3 ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines infections virales peuvent perturber la signalisation de MAPK3."
}
}
]
}
]
}
Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale
Validation scientifique effectuée le 18/02/2025
Contenu vérifié selon les dernières recommandations médicales
2 publications dans cette catégorie
Affiliations :
Division of Integrative Bioscience and Biotechnology, College of Life Sciences, Sejong University, Seoul 05006, Republic of Korea.
Publications dans "Mitogen-Activated Protein Kinase 3" :
2 publications dans cette catégorie
Affiliations :
From the Division of Pharmacology (M.S., K.J., K.H.), CSIR-Central Drug Research Institute, Lucknow, India.
Academy of Scientific and Innovative Research, Ghaziabad, India (M.S., K.J., K.H.).
Publications dans "Mitogen-Activated Protein Kinase 3" :
2 publications dans cette catégorie
Affiliations :
From the Division of Pharmacology (M.S., K.J., K.H.), CSIR-Central Drug Research Institute, Lucknow, India.
Academy of Scientific and Innovative Research, Ghaziabad, India (M.S., K.J., K.H.).
Publications dans "Mitogen-Activated Protein Kinase 3" :
2 publications dans cette catégorie
Affiliations :
Division of Molecular and Structural Biology (N.K.V., J.K.G.), CSIR-Central Drug Research Institute, Lucknow, India.
Publications dans "Mitogen-Activated Protein Kinase 3" :
2 publications dans cette catégorie
Affiliations :
Division of Molecular and Structural Biology (N.K.V., J.K.G.), CSIR-Central Drug Research Institute, Lucknow, India.
Publications dans "Mitogen-Activated Protein Kinase 3" :
2 publications dans cette catégorie
Affiliations :
Institute for Zellbiochemie, Medizinische Hochschule Hannover (MHH), Hanover, Germany (M.G.).
Publications dans "Mitogen-Activated Protein Kinase 3" :
2 publications dans cette catégorie
Affiliations :
From the Division of Pharmacology (M.S., K.J., K.H.), CSIR-Central Drug Research Institute, Lucknow, India.
Academy of Scientific and Innovative Research, Ghaziabad, India (M.S., K.J., K.H.).
Publications dans "Mitogen-Activated Protein Kinase 3" :
2 publications dans cette catégorie
Affiliations :
Department of Radiology, Hubei Provincial Hospital of Traditional Chinese Medicine, Wuhan, Hubei, China.
Publications dans "Mitogen-Activated Protein Kinase 3" :
1 publication dans cette catégorie
Affiliations :
Department of Life Science (BK21 program), Chung-Ang University, Seoul, South Korea.
Publications dans "Mitogen-Activated Protein Kinase 3" :
1 publication dans cette catégorie
Affiliations :
Department of Life Science (BK21 program), Chung-Ang University, Seoul, South Korea.
Publications dans "Mitogen-Activated Protein Kinase 3" :
1 publication dans cette catégorie
Affiliations :
Department of Life Science (BK21 program), Chung-Ang University, Seoul, South Korea.
Publications dans "Mitogen-Activated Protein Kinase 3" :
1 publication dans cette catégorie
Affiliations :
Department of Life Science (BK21 program), Chung-Ang University, Seoul, South Korea.
Publications dans "Mitogen-Activated Protein Kinase 3" :
1 publication dans cette catégorie
Affiliations :
College of Horticulture, Northwest A&F University, Yangling 712100, China. tayebmuhammad@nwsuaf.edu.cn.
State Key Laboratory of Crop Stress Biology in Arid Regions, Northwest A&F University, Yangling 712100, China. tayebmuhammad@nwsuaf.edu.cn.
Publications dans "Mitogen-Activated Protein Kinase 3" :
1 publication dans cette catégorie
Affiliations :
College of Horticulture, Northwest A&F University, Yangling 712100, China. 15591858981@163.com.
State Key Laboratory of Crop Stress Biology in Arid Regions, Northwest A&F University, Yangling 712100, China. 15591858981@163.com.
Publications dans "Mitogen-Activated Protein Kinase 3" :
1 publication dans cette catégorie
Affiliations :
College of Horticulture, Northwest A&F University, Yangling 712100, China. 15891785931@163.com.
State Key Laboratory of Crop Stress Biology in Arid Regions, Northwest A&F University, Yangling 712100, China. 15891785931@163.com.
Publications dans "Mitogen-Activated Protein Kinase 3" :
1 publication dans cette catégorie
Affiliations :
College of Horticulture, Northwest A&F University, Yangling 712100, China. liyushunaf@163.com.
State Key Laboratory of Crop Stress Biology in Arid Regions, Northwest A&F University, Yangling 712100, China. liyushunaf@163.com.
Publications dans "Mitogen-Activated Protein Kinase 3" :
1 publication dans cette catégorie
Affiliations :
College of Horticulture, Northwest A&F University, Yangling 712100, China. feizhang@nwsuaf.edu.cn.
Publications dans "Mitogen-Activated Protein Kinase 3" :
1 publication dans cette catégorie
Affiliations :
College of Horticulture, Northwest A&F University, Yangling 712100, China. zhangyan2014@nwsuaf.edu.cn.
State Key Laboratory of Crop Stress Biology in Arid Regions, Northwest A&F University, Yangling 712100, China. zhangyan2014@nwsuaf.edu.cn.
Publications dans "Mitogen-Activated Protein Kinase 3" :
1 publication dans cette catégorie
Affiliations :
College of Horticulture, Northwest A&F University, Yangling 712100, China. liangyan@nwsuaf.edu.cn.
State Key Laboratory of Crop Stress Biology in Arid Regions, Northwest A&F University, Yangling 712100, China. liangyan@nwsuaf.edu.cn.
Publications dans "Mitogen-Activated Protein Kinase 3" :
1 publication dans cette catégorie
Affiliations :
Division of Gastroenterology, Department of Medicine Jichi Medical University School of Medicine Shimotsuke Tochigi Japan.
Publications dans "Mitogen-Activated Protein Kinase 3" :
AKI is a potential complication of intravascular iodinated contrast exposure. Contrast-associated AKI, which typically manifests as small and transient decrements in kidney function that develop withi...
Intravenous iodinated contrast media are commonly used in clinical practice, ranging from medical imaging to interventional radiology (IR) procedures and endovascular interventions. Compared with pati...
Contrast associated acute kidney injury (CA-AKI) can lead to an increased risk of adverse events. Contrast media (CM) volume reduction has been advocated as a pivotal strategy to prevent CA-AKI in sta...
To compare the effectiveness of CM volume reduction with the DyeVert...
We prospectively collected data from 136 patients with stable coronary artery disease at high risk of CA-AKI treated with left ventricular end diastolic pressure (LVEDP)- guided hydration and undergoi...
Patients in the DyeVert group were treated with a significant lower CM volume (median: 47.5 vs. 84.0 mL, p < 0.001). The trend in creatinine increase was lower (p = 0.004) and the Δ of creatinine (0-4...
CM volume reduction with the DyeVert...
The aim of this study was to quantify the effect of iodinated contrast media (ICM) conservation measures implemented at a single health system during a global shortage, comparing the 12-month period b...
Total body weight (TBW) is a frequently used contrast media (CM) strategy for dose calculation in enhanced CT, yet it is suboptimal as it lacks consideration of patient characteristics, such as body f...
Eighty-nine adult patients referred for CM thoracic CT were retrospectively included, categorized as either normal, muscular, or overweight. Patient body composition data was used to calculate the CM ...
BIA demonstrated the highest and lowest calculated CM dose in muscular and overweight groups respectively, compared to other strategies. For the normal group, the lowest calculated CM dose was achieve...
The BIA method is more adaptive to variations in patient body habitus especially in muscular and overweight patients and is most closely correlated to patient demographics. This study could support ut...
The BIA-based method is adaptive to variations in body habitus especially in muscular and overweight patients and is closely correlated to patient demographics for contrast-enhanced chest CT....
• Calculations based on BIA showed the largest variation in CM dose. • Lean body weight using BIA demonstrated the strongest correlation to patient demographics. • Lean body weight BIA protocol may be...
A severe shortage of iodinated contrast medium (ICM) has forced radiology departments around the world to implement strategies to reduce contrast utilization. The aim of this study was to evaluate the...
Our radiology department instituted several ICM-conserving interventions on 13...
The average daily number of CECT (all), CECT (inpatient and ED), CTPA, CECT AP, and 'Code stroke' CT scans decreased significantly (P < 0.01), by 58.6%, 68.8%, 74.1%, 88.0%, and 37.5%, respectively. T...
Interventions in CT alone, focused on improving patient triage to CECT while avoiding deferment of any outpatient oncology studies, have achieved an approximately two-thirds reduction in ICM consumpti...
To identify the risk factors for moderate and severe contrast media extravasation and provide effective guidance to reduce the degree of extravasation injuries....
We observed 224 adult patients who underwent contrast media extravasation at Xiangya Hospital of Central South University, Hunan Provincial Maternal and Child Healthcare Hospital, and Xiangya Changde ...
Among 224 patients, 0 (0%) had severe, 18 (8.0%) had moderate, and 206 (92.0%) had mild contrast media extravasation injury. Multivariate logistic regression analysis revealed malignant tumors (odds r...
Risk factors for moderate contrast media extravasation injury are malignant tumors, iohexol, large-volume (> 50 mL) extravasation, and back-of-the-hand injection. Analysis of these risk factors can he...
High-risk patients with extravasation support should choose the appropriate contrast media type, avoiding back-of-the-hand injections. We recommend that patients with cancer be implanted with a high-p...
Iodinated- (ICM) and gadolinium-based (GCM) contrast media are used in radiology imaging techniques, such as computer tomography (CT) and magnetic resonance (MR), respectively. The paper aims to analy...
To assess the role of atorvastatin to the frequency of contrast-induced acute kidney injury (CI-AKI) in patients with cardiovascular diseases (CVD) undergoing computed tomography (CT) with intravenous...
One hundred patients with CVD undergoing CT with with intravenous contrast media administration were included in prospective observational study (ClinicalTrials.gov ID NCT04666389). Patients were divi...
CI-AKI was diagnosed in 4 (3.96%) patients. At the same time, it was not possible to establish statistically significant relationships (p0.05) between risk factors and the development of CI-AKI. Stati...
Cardiovascular diseases may increase the risk of CI-AKI after computed tomography with intravenous contrast media administration. Therefore, it is recommended to evaluate the serum creatinine concentr...
To pool and summarise published data of pulmonary blood flow (PBF), pulmonary blood volume (PBV) and mean transit time (MTT) of the human lung, obtained with perfusion MRI or CT to provide reliable re...
PubMed was systematically searched to identify studies that quantified PBF/PBV/MTT in the human lung by injection of contrast agent, imaged by MRI or CT. Only data analysed by 'indicator dilution theo...
PBV was obtained from 313 measurements from 14 publications (wM: 13.97 ml/100 ml, wSD: 4.21 ml/100 ml, wCoV 0.30). MTT was obtained from 188 measurements from 10 publications (wM: 5.91 s, wSD: 1.84 s ...
Reference values for PBF, MTT and PBV were obtained in HV. The literature data are insufficient to draw strong conclusions regarding disease reference values....