Naturalis Biodiversity Center, P.O. Box 9517, 2300 RA Leiden, Netherlands; Instituto Dom Luiz da Universidade de Lisboa, Campo Grande, 1749-016 Lisboa, Portugal; and International Health Centres, Av. Infante de Henrique 7, Areias São João, P-8200 Albufeira, Portugal.. bernielandau@sapo.pt.
Animal Systematics Research Unit, Department of Biology, Faculty of Science, Chulalongkorn University, Bangkok 10330, Thailand Chulalongkorn University Bangkok Thailand.
Animal Systematics Research Unit, Department of Biology, Faculty of Science, Chulalongkorn University, Bangkok 10330, Thailand Chulalongkorn University Bangkok Thailand.
Animal Systematics Research Unit, Department of Biology, Faculty of Science, Chulalongkorn University, Bangkok 10330, Thailand Chulalongkorn University Bangkok Thailand.
Centre for Agricultural Research, Plant Protection Institute, Eötvös Loránd Research Network, H-1022 Budapest, Herman Ottó út 15, Hungary.. pallgergely2@gmail.com.
Institut Systématique Evolution Biodiversité (ISYEB), Muséum National d'Histoire Naturelle, CNRS, EPHE Sorbonne Université, Université des Antilles Paris France.
A. N. Severtsov Institute of Ecology and Evolution Russian Academy of Sciences Moscow Russia.
Institut Systématique Evolution Biodiversité (ISYEB), Muséum National d'Histoire Naturelle, CNRS, EPHE Sorbonne Université, Université des Antilles Paris France.
A. N. Severtsov Institute of Ecology and Evolution Russian Academy of Sciences Moscow Russia.
Institut Systématique Evolution Biodiversité (ISYEB), Muséum National d'Histoire Naturelle, CNRS, EPHE Sorbonne Université, Université des Antilles Paris France.
Institut Systématique Evolution Biodiversité (ISYEB), Muséum National d'Histoire Naturelle, CNRS, EPHE Sorbonne Université, Université des Antilles Paris France.
Department of Biology, Hong Kong Baptist University, 224 Waterloo Road, Kowloon, Hong Kong, China. E-mail: qiujw@hkbu.edu.hk (Qiu); hujuntong9@gmail.com (Hu), yanjiezhang@hkbu.edu.hk (Zhang), jamesxie@hkbu.edu.hk (Xie).
Department of Biology, Hong Kong Baptist University, 224 Waterloo Road, Kowloon, Hong Kong, China. E-mail: qiujw@hkbu.edu.hk (Qiu); hujuntong9@gmail.com (Hu), yanjiezhang@hkbu.edu.hk (Zhang), jamesxie@hkbu.edu.hk (Xie).
Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou), 511458, China.
Department of Biology, Hong Kong Baptist University, 224 Waterloo Road, Kowloon, Hong Kong, China. E-mail: qiujw@hkbu.edu.hk (Qiu); hujuntong9@gmail.com (Hu), yanjiezhang@hkbu.edu.hk (Zhang), jamesxie@hkbu.edu.hk (Xie).
Department of Biology, Hong Kong Baptist University, 224 Waterloo Road, Kowloon, Hong Kong, China. E-mail: qiujw@hkbu.edu.hk (Qiu); hujuntong9@gmail.com (Hu), yanjiezhang@hkbu.edu.hk (Zhang), jamesxie@hkbu.edu.hk (Xie).
Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou), 511458, China.
In this paper, we use a fixed template of slots for the online scheduling of appointments. The template is a link between planning the service capacity at a tactical level and online scheduling at an ...
Elotuzumab in combination with dexamethasone and immunomodulating agents (IMiDs) lenalidomide or pomalidomide is 2nd to 4th line therapy for multiple myeloma. The labelled dosage of dexamethasone for ...
Apnea and intermittent hypoxemia (IH) are common developmental disorders in infants born earlier than 37 weeks' gestation. Caffeine administration has been shown to lower the incidence of these disord...
To evaluate the effects of early versus late discontinuation of caffeine administration in preterm infants....
We searched CENTRAL, PubMed, Embase, and three trial registries in August 2023; we applied no date limits. We checked the references of included studies and related systematic reviews....
We included randomized controlled trials (RCTs) in preterm infants born earlier than 37 weeks' gestation, up to a PMA of 44 weeks and 0 days, who received caffeine for any indication for at least seve...
We used standard Cochrane methods. Primary outcomes were: restarting caffeine therapy, intubation within one week of treatment discontinuation, and the need for non-invasive respiratory support within...
We included three RCTs (392 preterm infants). Discontinuation of caffeine at PMA less than 35 weeks' gestation versus PMA equal to or longer than 35 weeks' gestation This comparison included one singl...
There may be little or no difference in the incidence of all-cause mortality and apnea in infants who were randomized to later discontinuation of caffeine treatment. However, the number of infants wit...
Cetuximab (Cmab) plays an important role in the treatment for recurrent or metastatic head and neck cancer (R/M HNC). To date, however, no safety data on biweekly administration of cetuximab at a dose...
We retrospectively reviewed the clinical records of five R/M HNC patients who received biweekly Cmab in our institute between January 2016 and September 2021 and compared the safety profile between tw...
All patients initially received Cmab in combination with chemotherapy. Chemotherapy consisted of paclitaxel plus carboplatin in two patients, cisplatin + 5-FU in one patient, and paclitaxel in two pat...
Biweekly Cmab was well tolerated and did not demonstrate severe toxicities related to Cmab for R/M HNC....
Tyrosine kinase inhibitors (TKIs) have demonstrated significant efficacy against various types of cancers through molecular targeting mechanisms. Over the past 22 years, more than 100 TKIs have been a...
The standard meropenem (MEPM) regimen allowed by insurance in Japan is 0.5 g two or three times a day. Differences in dosages and administration schedules in Japan were evaluated....
Patients with bacteremia for whom MEPM was used as the initial treatment at our institution between 2016 and 2021 were included. We retrospectively investigated patients classified into two groups: th...
The probability of 100% fT > MIC was significantly higher in the high-dose group (96.4% vs 74.5%, odds ratio [OR] = 0.3, 95% confidence interval [CI] = 0.2-0.4, P = < 0.001). Regarding outcomes, the 3...
To improve outcomes in patients with bacteremia treated with MEPM, support for appropriate antimicrobial use is necessary for compliance with the dosage and administration schedule according to severe...
The growing evidence detailing the harmful effects of exposure to antibiotics has driven an urgency to evaluate recommendations in common pediatric infections regarding antibiotic course duration and ...
The optimal timing of tocilizumab treatment during the disease course of COVID-19 has yet to be adequately defined in the context of randomised controlled trials and the effect of tocilizumab on real-...
All adults (≥18 years old) with confirmed COVID-19 admitted to four hospitals in the West of Scotland between 8 January 2021 and 31 March 2021 and who received tocilizumab were included in a retrospec...
203 patients were included in the analysis (138 in the early cohort, 65 in the late cohort). Mortality in 90 days in the early cohort was 22% (n=30) compared with 45% (n=29) in the late cohort (p<0.00...
Early administration of tocilizumab within the first 2 days of hospitalisation was associated with a significant survival benefit compared with late exposure. Late administration was associated with p...
Hospice and palliative care have been shown to increase patient satisfaction and improve symptom control at the end of life. Opioid analgesics are typically given around the clock at the end of life t...
This was a retrospective, quasi-experimental study at a 766-bed community hospital with hospice and palliative care services. Adult patients admitted to inpatient hospice care with active orders for s...
A total of 75 patients were included in the final analysis. The rate of missed doses was 5% in the pre-implementation cohort and 4% in the post-implementation cohort (...
The creation and dissemination of nursing education were not associated with a decrease in missed or delayed doses of scheduled opioids in hospice patients....
An improved optimal drug scheduling model with considering two control drugs is proposed and the Gauss pseudospectral-based optimization method is studied to decrease the tumor size and drug toxicity ...