questionsmedicales.fr
Maladies du système immunitaire
Maladies auto-immunes
Maladie de Basedow
Ophtalmopathie basedowienne
Ophtalmopathie basedowienne : Questions médicales fréquentes
Termes MeSH sélectionnés :
Matrix Metalloproteinase 3
Diagnostic
5
Ophtalmopathie
Maladie de Basedow
Thyroïdite
Imagerie par résonance magnétique
Échographie
Thyroïde
Exophtalmie
Diplopie
Paupière
Hormones thyroïdiennes
Anticorps
Thyroïde
Diagnostic différentiel
Exophtalmie
Maladies oculaires
Symptômes
5
Exophtalmie
Sécheresse oculaire
Douleur oculaire
Diplopie
Muscles oculaires
Vision
Vision
Vision floue
Troubles visuels
Paupières
Inflammation
Gonflement
Symptômes
Variabilité
Maladie
Prévention
5
Prévention
Maladie de Basedow
Thyroïde
Tabagisme
Risque
Symptômes
Stress
Gestion du stress
Santé
Examens médicaux
Détection précoce
Santé oculaire
Alimentation
Santé thyroïdienne
Santé oculaire
Traitements
5
Corticostéroïdes
Radiothérapie
Chirurgie
Corticostéroïdes
Inflammation
Symptômes
Chirurgie
Exophtalmie
Vision
Radiothérapie
Tissus orbitaires
Inflammation
Larmes artificielles
Lunettes prismatiques
Traitements non médicamenteux
Complications
5
Complications
Perte de vision
Nerfs optiques
Perte de vision
Récupération
Gravité
Esthétique
Exophtalmie
Paupières
Nerfs optiques
Inflammation
Vision
Complications
Suivi médical
Traitement
Facteurs de risque
5
Facteurs de risque
Hyperthyroïdie
Antécédents familiaux
Antécédents familiaux
Maladies thyroïdiennes
Risque
Stress
Facteurs de risque
Symptômes
Femmes
Risque
Ophtalmopathie
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"text": "Le diagnostic repose sur l'examen clinique, l'imagerie et des tests sanguins pour évaluer la fonction thyroïdienne."
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{
"@type": "Question",
"name": "Quels examens sont utilisés pour le diagnostic ?",
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"@type": "Question",
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"name": "Les symptômes peuvent-ils varier d'une personne à l'autre ?",
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"name": "Le tabagisme influence-t-il la maladie ?",
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"position": 15,
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"position": 16,
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"position": 18,
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"name": "La radiothérapie est-elle courante ?",
"position": 19,
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"position": 20,
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"@type": "Question",
"name": "Quelles sont les complications possibles ?",
"position": 21,
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"@type": "Answer",
"text": "Les complications incluent la perte de vision, l'atteinte des nerfs optiques et des problèmes esthétiques."
}
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{
"@type": "Question",
"name": "La perte de vision est-elle réversible ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "Cela dépend de la gravité de l'atteinte; certaines pertes peuvent être permanentes."
}
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{
"@type": "Question",
"name": "Quels problèmes esthétiques peuvent survenir ?",
"position": 23,
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"text": "Des problèmes esthétiques incluent l'exophtalmie et des modifications des paupières."
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"@type": "Question",
"name": "Les nerfs optiques peuvent-ils être affectés ?",
"position": 24,
"acceptedAnswer": {
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"text": "Oui, l'inflammation peut entraîner une compression des nerfs optiques, affectant la vision."
}
},
{
"@type": "Question",
"name": "Y a-t-il des risques de complications après traitement ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des complications peuvent survenir même après un traitement, nécessitant un suivi."
}
},
{
"@type": "Question",
"name": "Quels sont les principaux facteurs de risque ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les facteurs incluent l'hyperthyroïdie, le tabagisme et des antécédents familiaux."
}
},
{
"@type": "Question",
"name": "L'âge influence-t-il le risque ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le risque augmente généralement avec l'âge, surtout chez les femmes de 30 à 50 ans."
}
},
{
"@type": "Question",
"name": "Les antécédents familiaux jouent-ils un rôle ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, un historique familial de maladies thyroïdiennes augmente le risque d'ophtalmopathie."
}
},
{
"@type": "Question",
"name": "Le stress peut-il être un facteur de risque ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le stress peut déclencher ou aggraver les symptômes de l'ophtalmopathie."
}
},
{
"@type": "Question",
"name": "Les femmes sont-elles plus à risque ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les femmes sont plus souvent touchées par l'ophtalmopathie de Basedow que les hommes."
}
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}
Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale
Validation scientifique effectuée le 23/03/2025
Contenu vérifié selon les dernières recommandations médicales
4 publications dans cette catégorie
Affiliations :
University of Health Sciences, Ulucanlar Eye Education and Research Hospital, Ankara, Turkey.
Publications dans "Ophtalmopathie basedowienne" :
4 publications dans cette catégorie
Affiliations :
University of Health Sciences, Ulucanlar Eye Education and Research Hospital, Ankara, Turkey.
Publications dans "Ophtalmopathie basedowienne" :
3 publications dans cette catégorie
Affiliations :
School of Basic Medical Science, Special Key Laboratory of Ocular Diseases of Guizhou Province, Zunyi Medical University, Zunyi, 563000, China.
Publications dans "Ophtalmopathie basedowienne" :
3 publications dans cette catégorie
Affiliations :
Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy.
Publications dans "Ophtalmopathie basedowienne" :
3 publications dans cette catégorie
Affiliations :
Department of Surgical, Medical and Molecular Pathology and Critical Area, University of Pisa, Pisa, Italy.
Publications dans "Ophtalmopathie basedowienne" :
3 publications dans cette catégorie
Affiliations :
Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.
Publications dans "Ophtalmopathie basedowienne" :
3 publications dans cette catégorie
Affiliations :
Department of Endocrinology and Metabolism, Shunde Hospital of Southern Medical University (The First People's Hospital of Shunde), Foshan, China.
The Second School of Clinical Medicine, Southern Medical University, Guangzhou, China.
Publications dans "Ophtalmopathie basedowienne" :
3 publications dans cette catégorie
Affiliations :
Biomedical Commercialization Center, Taipei Medical University, Taipei 11031, Taiwan.
Publications dans "Ophtalmopathie basedowienne" :
3 publications dans cette catégorie
Affiliations :
Department of Ophthalmology, Taipei Veterans General Hospital, Taipei 11217, Taiwan.
School of Medicine, National Yang Ming University, Taipei 11221, Taiwan.
School of Medicine, National Yang Ming Chiao Tung University, Hsinchu 30010, Taiwan.
Publications dans "Ophtalmopathie basedowienne" :
3 publications dans cette catégorie
Affiliations :
Department of Ophthalmology, National Taiwan University Hospital, Taipei 100225, Taiwan.
Publications dans "Ophtalmopathie basedowienne" :
3 publications dans cette catégorie
Affiliations :
Department of Ophthalmology, National Taiwan University Hospital, Taipei 100225, Taiwan.
Publications dans "Ophtalmopathie basedowienne" :
2 publications dans cette catégorie
Affiliations :
Department of Ophthalmology, Changzheng Hospital of Naval Medicine University, Shanghai, China.
Publications dans "Ophtalmopathie basedowienne" :
2 publications dans cette catégorie
Affiliations :
Department of Biochemistry and Pharmacogenomics, Faculty of Pharmacy, Medical University of Warsaw, Warsaw, Poland.
Laboratory of Biochemistry and Clinical Chemistry at the Centre for Preclinical Research, Medical University of Warsaw, Warsaw, Poland.
Publications dans "Ophtalmopathie basedowienne" :
2 publications dans cette catégorie
Affiliations :
Department of Internal Medicine and Endocrinology, Medical University of Warsaw, Warsaw, Poland.
Publications dans "Ophtalmopathie basedowienne" :
2 publications dans cette catégorie
Affiliations :
Chair and Department of Biochemistry, First Faculty of Medicine, Medical University of Warsaw, Warsaw, Poland.
Publications dans "Ophtalmopathie basedowienne" :
2 publications dans cette catégorie
Affiliations :
Department of Otolaryngology, Medical Center for Postgraduate Education, Warsaw, Poland.
Publications dans "Ophtalmopathie basedowienne" :
2 publications dans cette catégorie
Affiliations :
Department of Otolaryngology, Medical Center for Postgraduate Education, Warsaw, Poland.
Publications dans "Ophtalmopathie basedowienne" :
2 publications dans cette catégorie
Affiliations :
Chair and Department of Biochemistry, First Faculty of Medicine, Medical University of Warsaw, Warsaw, Poland.
Department of Otolaryngology, Medical Center for Postgraduate Education, Warsaw, Poland.
Publications dans "Ophtalmopathie basedowienne" :
2 publications dans cette catégorie
Affiliations :
Department of Ophthalmology, Third Xiangya Hospital, Central South University, Yuelu District, 138 Tongzipo Road, Changsha, 410013, Hunan, People's Republic of China.
Publications dans "Ophtalmopathie basedowienne" :
2 publications dans cette catégorie
Affiliations :
Department of Ophthalmology, Third Xiangya Hospital, Central South University, Yuelu District, 138 Tongzipo Road, Changsha, 410013, Hunan, People's Republic of China. weixiong420@csu.edu.cn.
Publications dans "Ophtalmopathie basedowienne" :
To develop a highly sensitive time-resolved fluorescence immunoassay (TRFIA) for the detection of serum matrix metalloproteinase-3 (MMP-3) and to assess MMP-3's clinical value in patients with colorec...
MMP-3 levels were established using the double antibody sandwich technique. The MMP-3 TRFIA technique was developed and optimized, and its linearity, sensitivity, accuracy, specificity, and recovery w...
The linear range of MMP-3 TRFIA was 0.73-500 ng/mL. MMP-3 TRFIA had an intra-batch precision range of 2.16%-7.10% percent and an inter-batch precision range of 3.99%-11.21%. MMP-3, tumor-associated tr...
A highly sensitive MMP-3 TRFIA assay was successfully developed, and serum MMP-3 may be associated with CRC invasion and metastasis. Therefore, MMP-3 can be used in the auxiliary diagnosis of CRC....
Anti-citrullinated protein antibodies (ACPAs) are highly specific for the diagnosis of rheumatoid arthritis (RA). However, about one-third of RA patients are negative for ACPAs, which presents a chall...
A highly sensitive and selective electrogenerated chemiluminescence (ECL) biosensor was developed for the determination of matrix metalloproteinase 3 (MMP-3) in serum via the target-induced cleavage o...
Metalloproteinases-3 (MMP3) are the main enzymes involved in cartilage degradation. Several genetic and non-genetic factors can increase the expression of MMP3 in patients with osteoarthritis (OA). Th...
A cross-sectional study was conducted at the orthopedic polyclinic Arifin Achmad Riau Province and Ibn Sina Hospital in Pekanbaru City. Ninety women who experienced knee OA were taken as samples by co...
The MMP3 rs679620 gene polymorphism of the mutant type was 88.9%, with the same proportion of AG and GG alleles (44.4%). Subjects aged ≥ 60 years were 53.3%, 85.6% did not work and 84.4% had menopause...
Diabetic neuropathy and nephropathy are common complications of type 1 diabetes (T1D). The symptoms are often elusive in the early stages, and available diagnostic methods can be improved using biomar...
Matrix metalloproteinase-3 (MMP-3) is a proteolytic enzyme involved in acute respiratory distress syndrome (ARDS) pathophysiology that may serve as a lung-specific biomarker in ARDS....
This study was a secondary biomarker analysis of a subset of Albuterol for the Treatment of Acute Lung Injury (ALTA) trial patients to determine the prognostic value of MMP-3. Plasma sample MMP-3 was ...
A total of 100 unique patient samples were evaluated and the AUROC analysis of day three MMP-3 showed an AUROC of 0.77 for the prediction of 90-day mortality (95% confidence interval: 0.67-0.87), corr...
Day three MMP-3 concentration and difference in day zero and three MMP-3 concentrations demonstrated acceptable AUROCs for predicting 90-day mortality with a cut-point of 18.4 ng/mL and + 9.5 ng/mL, r...
Studies using salivary inflammatory biomarkers for diagnosing and monitoring the progression of periodontal disease have garnered increased attention in recent years. The present study aimed to identi...
A 6-week NSPT program was applied to 51 adults aged ≥ 20 years. The program involved scaling, root planing, and professional toothbrushing for healthy participants and those with periodontal disease. ...
All clinical parameters were improved in the periodontal disease groups following the NSPT course. Compared with healthy participants, the patients with periodontal disease showed increased concentrat...
The present study found that NSPT resulted in reductions of salivary MMP-3, -8, and -9, and identified the potential of MMP-3 as a biomarker in the diagnosis of periodontal disease. These findings may...
Matrix metalloproteinases (MMPs) are widely expressed in atherosclerosis lesions. The disequilibrium of MMPs driving to an overexpression or a lack of its level can be influenced by genetic variations...
A total of 168 patients with CAD were prospectively followed up over a period of 5 years. Genotypes for the MMP-3 (-1612 5 A/6A) and MMP-9 (-1562 C/T) polymorphisms were performed using PCR-RFLP. Thei...
Our study suggests the disruption of the MMP-3 level may be due to the existence of the polymorphism - 1612 residing in its promoter region. MMP-3 can be considered as a marker of diagnosis and predic...
Matrix metalloproteinases (MMPs) are involved in extracellular matrix remodeling through the degradation of extracellular matrix components and are also involved in the inflammatory response by regula...
Alzheimer's disease (AD) can be characterised in vivo by biomarkers reflecting amyloid-β (Aβ) and tau pathology. However, there is a need for biomarkers reflecting additional pathological pathways. Ma...
In this cross-sectional study, we investigated nine MMPs and four tissue inhibitors of metalloproteinases (TIMPs) in the cerebrospinal fluid of 256 memory clinic patients with mild cognitive impairmen...
MMP-10 and TIMP-2 levels differed significantly between the memory clinic patients and the cognitively unimpaired controls. Furthermore, MMP- and TIMP-levels were generally strongly associated with ta...
Our results support the use of MMPs/TIMPs as markers of sex differences and progression in AD. Our findings show sex-specific effects of MMP-3 and TIMP-4 on amyloid pathology. Further, this study high...