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"description": "Comment la spectroscopie diélectrique aide-t-elle au diagnostic ?\nQuels types de maladies peuvent être diagnostiqués ?\nLa spectroscopie peut-elle détecter des anomalies précoces ?\nEst-elle utilisée en complément d'autres techniques ?\nQuels sont les avantages de cette méthode de diagnostic ?",
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"description": "Quelles complications peuvent survenir lors de l'utilisation ?\nPeut-elle causer des effets secondaires ?\nY a-t-il des risques liés à l'interprétation des résultats ?\nLes complications sont-elles fréquentes ?\nComment minimiser les complications potentielles ?",
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"name": "Facteurs de risque",
"headline": "Facteurs de risque sur Spectroscopie diélectrique",
"description": "Quels facteurs de risque sont associés aux maladies détectées ?\nLa génétique joue-t-elle un rôle ?\nLes habitudes alimentaires influencent-elles les résultats ?\nLe mode de vie a-t-il un impact sur les risques ?\nLes facteurs environnementaux sont-ils significatifs ?",
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"@type": "Question",
"name": "Comment la spectroscopie diélectrique aide-t-elle au diagnostic ?",
"position": 1,
"acceptedAnswer": {
"@type": "Answer",
"text": "Elle permet d'analyser les propriétés des tissus biologiques, facilitant le diagnostic de maladies."
}
},
{
"@type": "Question",
"name": "Quels types de maladies peuvent être diagnostiqués ?",
"position": 2,
"acceptedAnswer": {
"@type": "Answer",
"text": "Elle est utilisée pour diagnostiquer des cancers, des maladies neurologiques et des troubles métaboliques."
}
},
{
"@type": "Question",
"name": "La spectroscopie peut-elle détecter des anomalies précoces ?",
"position": 3,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, elle peut identifier des changements subtils dans les tissus avant l'apparition des symptômes."
}
},
{
"@type": "Question",
"name": "Est-elle utilisée en complément d'autres techniques ?",
"position": 4,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, elle est souvent combinée avec l'IRM ou l'échographie pour une évaluation plus complète."
}
},
{
"@type": "Question",
"name": "Quels sont les avantages de cette méthode de diagnostic ?",
"position": 5,
"acceptedAnswer": {
"@type": "Answer",
"text": "Elle est non invasive, rapide et fournit des informations sur la composition des tissus."
}
},
{
"@type": "Question",
"name": "Quels symptômes peuvent être détectés par cette technique ?",
"position": 6,
"acceptedAnswer": {
"@type": "Answer",
"text": "Elle peut aider à identifier des symptômes liés à des anomalies tissulaires, comme des douleurs."
}
},
{
"@type": "Question",
"name": "Peut-elle évaluer des symptômes neurologiques ?",
"position": 7,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, elle peut analyser des changements dans les tissus cérébraux associés à des troubles neurologiques."
}
},
{
"@type": "Question",
"name": "Les symptômes métaboliques peuvent-ils être évalués ?",
"position": 8,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, elle permet d'étudier les modifications des tissus liés à des troubles métaboliques."
}
},
{
"@type": "Question",
"name": "Est-elle utile pour les symptômes liés au cancer ?",
"position": 9,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, elle aide à détecter des changements dans les tissus tumoraux, facilitant le suivi."
}
},
{
"@type": "Question",
"name": "Peut-elle identifier des symptômes précoces ?",
"position": 10,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, elle peut détecter des modifications tissulaires avant l'apparition de symptômes cliniques."
}
},
{
"@type": "Question",
"name": "La spectroscopie peut-elle aider à la prévention des maladies ?",
"position": 11,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, elle permet de détecter des changements précoces, facilitant des interventions préventives."
}
},
{
"@type": "Question",
"name": "Peut-elle être utilisée dans des programmes de dépistage ?",
"position": 12,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, elle peut être intégrée dans des programmes de dépistage pour des maladies spécifiques."
}
},
{
"@type": "Question",
"name": "Est-elle utile pour surveiller les facteurs de risque ?",
"position": 13,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, elle aide à évaluer les modifications tissulaires liées à des facteurs de risque connus."
}
},
{
"@type": "Question",
"name": "Peut-elle contribuer à l'éducation des patients ?",
"position": 14,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, elle peut sensibiliser les patients aux changements tissulaires et à leur santé."
}
},
{
"@type": "Question",
"name": "Est-elle utilisée pour des conseils de mode de vie ?",
"position": 15,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, elle peut fournir des données pour conseiller des changements de mode de vie préventifs."
}
},
{
"@type": "Question",
"name": "La spectroscopie aide-t-elle à choisir un traitement ?",
"position": 16,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, elle fournit des informations sur la réponse des tissus aux traitements, guidant les décisions."
}
},
{
"@type": "Question",
"name": "Peut-elle évaluer l'efficacité d'un traitement ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, elle permet de suivre les changements dans les tissus pendant et après le traitement."
}
},
{
"@type": "Question",
"name": "Est-elle utilisée pour personnaliser les traitements ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, elle aide à adapter les traitements en fonction des caractéristiques spécifiques des tissus."
}
},
{
"@type": "Question",
"name": "Peut-elle guider la radiothérapie ?",
"position": 19,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, elle peut aider à cibler les zones à traiter en analysant les propriétés des tissus tumoraux."
}
},
{
"@type": "Question",
"name": "Est-elle utilisée dans la recherche de nouveaux traitements ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, elle est employée pour étudier les effets de nouveaux médicaments sur les tissus."
}
},
{
"@type": "Question",
"name": "Quelles complications peuvent survenir lors de l'utilisation ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les complications sont rares, mais peuvent inclure des erreurs de mesure ou des interprétations incorrectes."
}
},
{
"@type": "Question",
"name": "Peut-elle causer des effets secondaires ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "Non, la spectroscopie diélectrique est non invasive et ne provoque pas d'effets secondaires."
}
},
{
"@type": "Question",
"name": "Y a-t-il des risques liés à l'interprétation des résultats ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, une mauvaise interprétation peut mener à des diagnostics erronés ou à des traitements inappropriés."
}
},
{
"@type": "Question",
"name": "Les complications sont-elles fréquentes ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "Non, les complications sont rares et la méthode est généralement considérée comme sûre."
}
},
{
"@type": "Question",
"name": "Comment minimiser les complications potentielles ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une formation adéquate des opérateurs et des protocoles standardisés peuvent réduire les risques."
}
},
{
"@type": "Question",
"name": "Quels facteurs de risque sont associés aux maladies détectées ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les facteurs incluent l'âge, les antécédents familiaux et les habitudes de vie."
}
},
{
"@type": "Question",
"name": "La génétique joue-t-elle un rôle ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des prédispositions génétiques peuvent augmenter le risque de certaines maladies détectées."
}
},
{
"@type": "Question",
"name": "Les habitudes alimentaires influencent-elles les résultats ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, une alimentation déséquilibrée peut affecter la santé des tissus et les résultats de la spectroscopie."
}
},
{
"@type": "Question",
"name": "Le mode de vie a-t-il un impact sur les risques ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le tabagisme, l'alcool et le manque d'exercice augmentent les risques de maladies."
}
},
{
"@type": "Question",
"name": "Les facteurs environnementaux sont-ils significatifs ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'exposition à des toxines ou à des polluants peut augmenter le risque de maladies."
}
}
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}
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Pigmentary mosaicism (PM), also known as Blaschkoid dyspigmentation, is a rare pigmentary anomaly. Although several case reports have been published describing extracutaneous manifestations associated...
To describe the clinical characteristics of patients with PM....
This descriptive cross-sectional study was conducted among 47 children examined by a dermatologist and a pediatrician. The pattern and location of the PM, type of pigmentation and extracutaneous manif...
The most common pattern of PM was narrow-band PM, followed by broad-band and checkerboard patterns. The trunk was the most affected region, followed by the legs and arms. PM manifested as hypopigmenta...
PM has been associated with several extracutaneous findings but there is still some debate whether these associations reflect different PM phenotypes or whether they are simply coincidental. Our study...
Vitiligo is an autoimmune skin disorder caused by dysfunctional pigment-producing melanocytes which are attacked by immune cells. Oxidative stress is considered to play a crucial role in activating co...
Multiple laser modalities have been used for melasma treatment. However, the effectiveness of picosecond laser in treating melasma remains unclear. This meta-analysis investigated the effectiveness an...
Dermoscopy is an important tool in general dermatology....
To show differences of light and dark skin in nonneoplastic diseases with focus on dermoscopy....
Using previously published studies, dermoscopic differences of various skin types as well as features of inflammatory diseases and pigmentary changes are illustrated....
Certain structures are more difficult to assess in dermoscopy of dark skin (e.g., vessels), while other structures (e.g., follicular openings) are more prominent....
The majority of studies on dermoscopy are from studies that predominantly included individuals with fair skin types. Further studies of individuals with skin type IV or higher are needed to improve di...
Chemical leukoderma is a skin depigmentation disorder induced through contact with certain chemicals, most of which have a p-substituted phenol structure similar to the melanin precursor tyrosine. The...
Our aim was to find an effective method to evaluate the formation of o-quinone by human tyrosinase and subsequent cellular reactions....
Human tyrosinase-expressing 293T cells were exposed to various phenolic compounds, after which the reactive o-quinones generated were identified as adducts of cellular thiols. We further examined whet...
Among the chemicals tested, all 7 leukoderma-inducing phenols/catechol (rhododendrol, raspberry ketone, monobenzone, 4-tert-butylphenol, 4-tert-butylcatechol, 4-S-cysteaminylphenol and p-cresol) were ...
We developed a cell-based metabolite analytical method to detect human tyrosinase-catalyzed formation of o-quinone from phenolic compounds by analyzing their thiol-adducts. The detailed analysis of ea...
Vitamin D receptor (VDR) polymorphisms may play an important role in the vitiligo susceptibility. There have been many studies looking at the associations between VDR polymorphisms and vitiligo risk, ...
This study aimed to determine whether polymorphisms in the VDR are associated to the susceptibility to vitiligo....
Vitamin D receptor polymorphisms in vitiligo patients and controls were identified using PubMed/Medline and Embase databases. The relationships between the VDR ApaI, TaqI, BsmI, and TaqI polymorphisms...
This meta-analysis included 13 papers with 2034 patients and 2771 controls. In all individuals, there was no link between vitiligo and the VDR ApaI A allele (OR = 0.889, 95% CI = 0.713-1.109, p = 0.29...
In the Asian population, ApaI and BsmI polymorphisms in VDR have been correlated to vitiligo susceptibility. However, TaqI and FokI polymorphisms in VDR are not associated with vitiligo susceptibility...
Autoimmune and metabolic disturbances have been reported in association with vitiligo, highlighting possible systemic associations that should be considered....
To assess the possible association of metabolic syndrome (MetS) as well as insulin resistance (IR) with vitiligo in different age groups....
This case-control study included 142 patients with vitiligo aging ≥ 6 years and 142 age- and sex-matched controls. Participants were assessed for MetS using the International Diabetes Federation (IDF)...
As per the IDF criteria, patients with vitiligo showed significantly more frequent association with high fasting plasma glucose levels, high blood pressure readings, central obesity, dyslipidemia, and...
Patients with vitiligo showed a significantly higher incidence of MetS than controls. Vitiligo per se can be considered a risk factor for MetS and IR. Therefore, regular follow-up and early metabolic ...
Nevus of Ota is a benign melanocytic lesion that presents as a unilateral blue gray to brown facial patch favoring the distribution of the first two branches of the trigeminal nerve. Incidence is high...
We performed a retrospective review of Black patients presenting with Nevus of Ota. Race was self-designated by all patients and documented in the medical record at the time of initial consultation. P...
Ten FST V or VI patients with an age range of 9 months to 45 years were treated for Nevus of Ota. All patients were treated with the 1064 nm Q-switched neodymium doped yttrium aluminum garnet (QS Nd:Y...
1064 nm QS Nd:YAG laser therapy is a safe and efficacious treatment for Nevus of Ota in patients with FST V and VI. When patient improvement plateaus, combining therapy with 1550 nm NAFR or transition...
Macular retinal pigment epithelium (RPE) hypopigmentation is a recently described very rare condition and its pathogenesis is not completely understood. We report the case of a 23-year-old female who ...
A 23-year-old female presented to our consideration for a routine ophthalmology visit. Visual acuity was 20/20 in both eyes. The fundus examination revealed a perifoveal choroidal nevus in the right e...
A complex dysregulation of both choroidal and RPE with melanin loss may be responsible for this condition....
Reflectance confocal microscopy (RCM) has quickly transitioned from a research tool to an adjunct diagnostic bedside tool, providing the opportunity for noninvasive evaluation of skin lesions with his...
We present a review of the current literature on the use of RCM in the diagnosis and management of pigmentary disorders....
We reviewed PubMed and Ovid Medline databases from January 2000 to June 2021, using MeSH key terms: "reflectance confocal microscopy, confocal laser scanning microscopy, pigmentary disorders, treatmen...
RCM findings of pigmentary disorders were divided into the following categories: (1) disorders of increased pigmentation (post-inflammatory hyperpigmentation, melasma, Riehl's melanosis, solar lentigi...
RCM has been explored and proven valuable for the evaluation and management of pigmentary disorders including melasma, vitiligo, solar lentigines, tattoo, and tattoo-related complications....
