Titre : Microdissection au laser

Microdissection au laser : Questions médicales fréquentes

Termes MeSH sélectionnés :

Colorectal Neoplasms
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Microdissection au laser - Questions et réponses", "headline": "Questions et réponses médicales fréquentes sur Microdissection au laser", "description": "Une compilation de questions et réponses structurées, validées par des experts médicaux.", "datePublished": "2025-05-04", "inLanguage": "fr", "hasPart": [ { "@type": "MedicalWebPage", "name": "Diagnostic", "headline": "Diagnostic sur Microdissection au laser", "description": "Comment la microdissection au laser est-elle utilisée en diagnostic ?\nQuels types de tissus peuvent être analysés ?\nLa microdissection au laser est-elle invasive ?\nQuels marqueurs sont utilisés pour identifier les cellules ?\nPeut-on utiliser cette technique pour le cancer ?", "url": "https://questionsmedicales.fr/mesh/D061346?mesh_terms=Colorectal+Neoplasms&page=2#section-diagnostic" }, { "@type": "MedicalWebPage", "name": "Symptômes", "headline": "Symptômes sur Microdissection au laser", "description": "Quels symptômes peuvent nécessiter une microdissection au laser ?\nLa microdissection peut-elle aider à identifier des maladies ?\nQuels signes cliniques sont associés aux tissus analysés ?\nLes symptômes sont-ils toujours visibles avant la microdissection ?\nComment les symptômes influencent-ils le choix de la technique ?", "url": "https://questionsmedicales.fr/mesh/D061346?mesh_terms=Colorectal+Neoplasms&page=2#section-symptômes" }, { "@type": "MedicalWebPage", "name": "Prévention", "headline": "Prévention sur Microdissection au laser", "description": "La microdissection au laser aide-t-elle à la prévention des maladies ?\nQuels facteurs de risque peuvent être identifiés ?\nPeut-on utiliser cette technique pour le dépistage ?\nComment la prévention est-elle améliorée par cette technique ?\nLa microdissection peut-elle aider à la recherche préventive ?", "url": "https://questionsmedicales.fr/mesh/D061346?mesh_terms=Colorectal+Neoplasms&page=2#section-prévention" }, { "@type": "MedicalWebPage", "name": "Traitements", "headline": "Traitements sur Microdissection au laser", "description": "La microdissection au laser est-elle un traitement ?\nComment les résultats influencent-ils le traitement ?\nPeut-on combiner cette technique avec d'autres traitements ?\nQuels traitements peuvent être guidés par cette technique ?\nLa microdissection aide-t-elle à évaluer l'efficacité des traitements ?", "url": "https://questionsmedicales.fr/mesh/D061346?mesh_terms=Colorectal+Neoplasms&page=2#section-traitements" }, { "@type": "MedicalWebPage", "name": "Complications", "headline": "Complications sur Microdissection au laser", "description": "Quelles complications peuvent survenir avec cette technique ?\nLa microdissection au laser peut-elle causer des dommages tissulaires ?\nY a-t-il des risques d'infection ?\nComment éviter les complications lors de l'utilisation ?\nLes complications affectent-elles les résultats ?", "url": "https://questionsmedicales.fr/mesh/D061346?mesh_terms=Colorectal+Neoplasms&page=2#section-complications" }, { "@type": "MedicalWebPage", "name": "Facteurs de risque", "headline": "Facteurs de risque sur Microdissection au laser", "description": "Quels facteurs de risque sont associés à l'utilisation de cette technique ?\nLa génétique joue-t-elle un rôle dans l'indication de cette technique ?\nL'environnement influence-t-il les risques associés ?\nLes habitudes de vie affectent-elles les risques ?\nComment évaluer les facteurs de risque avant la microdissection ?", "url": "https://questionsmedicales.fr/mesh/D061346?mesh_terms=Colorectal+Neoplasms&page=2#section-facteurs de risque" } ] }, { "@type": "FAQPage", "mainEntity": [ { "@type": "Question", "name": "Comment la microdissection au laser est-elle utilisée en diagnostic ?", "position": 1, "acceptedAnswer": { "@type": "Answer", "text": "Elle permet d'extraire des cellules spécifiques pour des analyses génétiques ou histologiques." } }, { "@type": "Question", "name": "Quels types de tissus peuvent être analysés ?", "position": 2, "acceptedAnswer": { "@type": "Answer", "text": "Des tissus tumoraux, embryonnaires ou autres échantillons biologiques peuvent être analysés." } }, { "@type": "Question", "name": "La microdissection au laser est-elle invasive ?", "position": 3, "acceptedAnswer": { "@type": "Answer", "text": "Non, c'est une méthode non invasive pour isoler des cellules sans endommager le tissu environnant." } }, { "@type": "Question", "name": "Quels marqueurs sont utilisés pour identifier les cellules ?", "position": 4, "acceptedAnswer": { "@type": "Answer", "text": "Des marqueurs spécifiques comme des anticorps ou des colorants peuvent être utilisés." } }, { "@type": "Question", "name": "Peut-on utiliser cette technique pour le cancer ?", "position": 5, "acceptedAnswer": { "@type": "Answer", "text": "Oui, elle est souvent utilisée pour étudier les cellules tumorales et leur microenvironnement." } }, { "@type": "Question", "name": "Quels symptômes peuvent nécessiter une microdissection au laser ?", "position": 6, "acceptedAnswer": { "@type": "Answer", "text": "Des symptômes liés à des tumeurs ou des anomalies cellulaires peuvent justifier cette technique." } }, { "@type": "Question", "name": "La microdissection peut-elle aider à identifier des maladies ?", "position": 7, "acceptedAnswer": { "@type": "Answer", "text": "Oui, elle permet d'identifier des maladies génétiques ou des pathologies spécifiques." } }, { "@type": "Question", "name": "Quels signes cliniques sont associés aux tissus analysés ?", "position": 8, "acceptedAnswer": { "@type": "Answer", "text": "Les signes peuvent inclure des masses, des douleurs ou des anomalies visibles à l'imagerie." } }, { "@type": "Question", "name": "Les symptômes sont-ils toujours visibles avant la microdissection ?", "position": 9, "acceptedAnswer": { "@type": "Answer", "text": "Pas toujours, certains changements cellulaires peuvent être asymptomatiques au début." } }, { "@type": "Question", "name": "Comment les symptômes influencent-ils le choix de la technique ?", "position": 10, "acceptedAnswer": { "@type": "Answer", "text": "Les symptômes orientent le choix de la technique pour cibler les cellules d'intérêt." } }, { "@type": "Question", "name": "La microdissection au laser aide-t-elle à la prévention des maladies ?", "position": 11, "acceptedAnswer": { "@type": "Answer", "text": "Indirectement, en permettant une détection précoce des anomalies cellulaires." } }, { "@type": "Question", "name": "Quels facteurs de risque peuvent être identifiés ?", "position": 12, "acceptedAnswer": { "@type": "Answer", "text": "Des facteurs génétiques ou environnementaux peuvent être identifiés par cette technique." } }, { "@type": "Question", "name": "Peut-on utiliser cette technique pour le dépistage ?", "position": 13, "acceptedAnswer": { "@type": "Answer", "text": "Oui, elle peut être utilisée pour le dépistage de certaines pathologies cellulaires." } }, { "@type": "Question", "name": "Comment la prévention est-elle améliorée par cette technique ?", "position": 14, "acceptedAnswer": { "@type": "Answer", "text": "Elle permet d'identifier des cellules à risque avant l'apparition de symptômes cliniques." } }, { "@type": "Question", "name": "La microdissection peut-elle aider à la recherche préventive ?", "position": 15, "acceptedAnswer": { "@type": "Answer", "text": "Oui, elle est utilisée dans la recherche pour comprendre les mécanismes de maladies." } }, { "@type": "Question", "name": "La microdissection au laser est-elle un traitement ?", "position": 16, "acceptedAnswer": { "@type": "Answer", "text": "Non, c'est une technique de prélèvement pour des analyses qui peuvent guider le traitement." } }, { "@type": "Question", "name": "Comment les résultats influencent-ils le traitement ?", "position": 17, "acceptedAnswer": { "@type": "Answer", "text": "Les résultats aident à personnaliser les traitements en fonction des caractéristiques cellulaires." } }, { "@type": "Question", "name": "Peut-on combiner cette technique avec d'autres traitements ?", "position": 18, "acceptedAnswer": { "@type": "Answer", "text": "Oui, elle peut être utilisée en complément d'autres méthodes comme la chimiothérapie." } }, { "@type": "Question", "name": "Quels traitements peuvent être guidés par cette technique ?", "position": 19, "acceptedAnswer": { "@type": "Answer", "text": "Des traitements ciblés, immunothérapies ou thérapies géniques peuvent être guidés." } }, { "@type": "Question", "name": "La microdissection aide-t-elle à évaluer l'efficacité des traitements ?", "position": 20, "acceptedAnswer": { "@type": "Answer", "text": "Oui, elle permet d'analyser les réponses cellulaires aux traitements administrés." } }, { "@type": "Question", "name": "Quelles complications peuvent survenir avec cette technique ?", "position": 21, "acceptedAnswer": { "@type": "Answer", "text": "Les complications sont rares, mais peuvent inclure des erreurs de prélèvement ou contamination." } }, { "@type": "Question", "name": "La microdissection au laser peut-elle causer des dommages tissulaires ?", "position": 22, "acceptedAnswer": { "@type": "Answer", "text": "Elle est conçue pour minimiser les dommages, mais un mauvais réglage peut causer des lésions." } }, { "@type": "Question", "name": "Y a-t-il des risques d'infection ?", "position": 23, "acceptedAnswer": { "@type": "Answer", "text": "Le risque d'infection est faible, car la technique est non invasive et stérile." } }, { "@type": "Question", "name": "Comment éviter les complications lors de l'utilisation ?", "position": 24, "acceptedAnswer": { "@type": "Answer", "text": "Une formation adéquate et un équipement calibré sont essentiels pour éviter les complications." } }, { "@type": "Question", "name": "Les complications affectent-elles les résultats ?", "position": 25, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des complications peuvent altérer la qualité des échantillons et les résultats finaux." } }, { "@type": "Question", "name": "Quels facteurs de risque sont associés à l'utilisation de cette technique ?", "position": 26, "acceptedAnswer": { "@type": "Answer", "text": "Les facteurs incluent l'âge, l'hérédité et l'exposition à des agents carcinogènes." } }, { "@type": "Question", "name": "La génétique joue-t-elle un rôle dans l'indication de cette technique ?", "position": 27, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des antécédents familiaux de maladies peuvent justifier l'utilisation de la microdissection." } }, { "@type": "Question", "name": "L'environnement influence-t-il les risques associés ?", "position": 28, "acceptedAnswer": { "@type": "Answer", "text": "Oui, l'exposition à des toxines environnementales peut augmenter les risques cellulaires." } }, { "@type": "Question", "name": "Les habitudes de vie affectent-elles les risques ?", "position": 29, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des habitudes comme le tabagisme ou une mauvaise alimentation peuvent influencer les risques." } }, { "@type": "Question", "name": "Comment évaluer les facteurs de risque avant la microdissection ?", "position": 30, "acceptedAnswer": { "@type": "Answer", "text": "Une évaluation clinique et historique complète est nécessaire pour identifier les facteurs de risque." } } ] } ] }

Sources (10000 au total)

Risk and preventive factors of early-onset colorectal neoplasms: endoscopic and histological database analysis.

The incidence of early-onset colorectal neoplasms has been increasing in both Western and Eastern countries. However, the risks and preventive factors for these neoplasms in Eastern countries remain u... The data of 5580 patients who underwent colonoscopy between 2016 and 2021 were retrospectively evaluated. The primary outcome was advanced colorectal neoplasm (ACRN), defined as advanced adenomas (ade... Among 1001 patients (age ≤50 years), ACRN was found in 94 (9.4%). In this younger category, male sex (adjusted odds ratio [aOR]:2.34, 95% confidence interval [CI]:1.51-3.63) and a family history of co... The development of early-onset ACRNs was primarily associated with congenital factors, whereas that of late-onset ACRNs was associated with acquired ones. Colonoscopy is recommended for young male pat...

Tip-in EMR as an alternative to endoscopic submucosal dissection for 20- to 30-mm nonpedunculated colorectal neoplasms.

Tip-in EMR, which includes anchoring the snare tip, has recently shown a favorable en-bloc and R0 resection rate for colorectal neoplasms. Thus, Tip-in EMR may be an alternative to endoscopic submucos... This retrospective study evaluated consecutive patients who underwent Tip-in EMR or ESD for 20- to 30-mm nonpedunculated colorectal neoplasms at a Japanese tertiary cancer center between January 2014 ... Seven hundred nine lesions were evaluated. The Tip-in EMR group included 1 lesion with a nonlifting sign but no lesions with fold convergence. After propensity score matching, each group included 140 ... Tip-in EMR is comparable with ESD with respect to the local recurrence rate but has a shorter procedure time, despite the lower en-bloc and R0 resection rates for 20- to 30-mm nonpedunculated colorect...

Clinical outcomes of endoscopic submucosal dissection for colorectal neoplasms: A single-center experience in Southern Taiwan.

Endoscopic submucosal dissection (ESD) as an advanced endoscopic procedure can be considered for the removal of colorectal lesions with high suspicion of limited submucosal invasion or cannot be optim... We retrospectively enrolled 230 patients with 244 colorectal neoplasms who received ESD procedures from April 2012 to October 2020 at Kaohsiung Chang Gung Memorial Hospital. Clinicopathological data w... The average age was 64 years old, with a mean follow-up time of 22.59 months. There was a loss of follow-up in 34 lesions. Most lesions were lateral spreading tumors of the non-granular type. The aver... ESD for colorectal neoplasms is an effective and safe technique. Size ≥ 10 cm2 and endoscopist's experience < 3 years were significantly associated with long procedure time. Pre-ESD EUS provided a goo...

Risk prediction of second primary malignancies in primary colorectal neuroendocrine neoplasms patients: a population-based study.

In this study, we aimed to identify risk factors for developing second primary malignancies (SPMs) in colorectal neuroendocrine neoplasms (NENs) patients and develop a competing-risk nomogram to predi... Patients with colorectal NENs were retrospectively collected from the Surveillance, Epidemiology, and End Results (SEER) database during 2000-2013. Potential risk factors for SPMs' occurrence in color... We identified 11,017 colorectal NENs' patients, and randomly divided them into training (n = 7711 patients) and validation (n = 3306 patients) cohorts. In the whole cohort, 12.4% patients (n = 1369) h... This research identified risk factors for SPMs' occurrence in colorectal NENs' patients. Competing-risk nomogram was constructed and proved to have good performance....

Treatment indicators and prognostic factors in colorectal neuroendocrine neoplasms and adenocarcinoma with neuroendocrine differentiation: a single center retrospective study.

This study compared survival and metastasis occurrence between colorectal neuroendocrine neoplasms (cNEN) and colorectal adenocarcinoma with neuroendocrine differentiation (cNED) and further explored ... Patients diagnosed as cNEN and cNED in West China Hospital from January 2009 to December 2020 were enrolled. The diagnosis and metastasis rates were calculated. Univariate and multivariate Cox analyse... The study enrolled 435 patients, including 257 neuroendocrine tumors (NET), 52 neuroendocrine carcinomas (NEC), 29 mixed neuroendocrine-non-neuroendocrine neoplasms (MiNEN), and 97 NED patients, of wh... cNEN show high metastatic capacity and are challenging to diagnose. More aggressive treatment and follow-up strategies are necessary for those patients. NET tumor grade higher than G2, size larger tha...

Pokemon inhibits Bim transcription to promote the proliferation, anti-anoikis, invasion, histological grade, and dukes stage of colorectal neoplasms.

This study aims to determine whether Pokemon regulates Bim activity in colorectal carcinoma (CRC) carcinogenesis.... Clinical tissue samples were analyzed to detect the expression and clinicopathological significance of Pokemon and Bim in CRC. Proliferation, apoptosis, and invasion assays were conducted to identify ... Immunohistochemical analysis of 80 samples of colorectal epithelia (CRE), 80 cases of colorectal adenoma (CRA), and 160 of CRC samples revealed protein expression rates of 23.8%, 38.8%, and 70.6% for ... These findings suggest that Pokemon inhibits Bim transcription, thereby promoting CRC proliferation, resistance to apoptosis, invasion, and advancing histological grade and Dukes staging. Pokemon knoc...

Endoscopic submucosal tunnel dissection vs conventional endoscopic submucosal dissection for large colorectal neoplasms: a single-centre retrospective study.

Colorectal endoscopic submucosal dissection (ESD) is still not widely used due to its technical difficulty and the risk of complications. Several techniques, such as traction techniques, pocket techni... The charts of consecutive patients referred to the Arcispedale Santa Maria Nuova (Reggio Emilia, Italy) for colorectal ESD between January 2014 and February 2021 for colorectal neoplasms > 40 mm were ... There were 59 patients (M:F ratio 29:30, median age 70 years [range 50-93 years]). Of 59 colorectal lesions > 40 mm, 25 were removed by ESTD and 34 by CESD. The en bloc resection rate was 100% in both... ESTD achieves a very high en bloc resection rate and is faster than CESD....