Titre : Tests de dépistage du sérum maternel

Tests de dépistage du sérum maternel : Questions médicales fréquentes

Termes MeSH sélectionnés :

Case-Control Studies

Questions fréquentes et termes MeSH associés

Diagnostic 5

#1

Quels tests sont inclus dans le dépistage du sérum maternel ?

Les tests incluent le test de la protéine plasmatique A et le test de l'hormone chorionique.
Dépistage prénatal Protéine plasmatique A Hormone chorionique
#2

Quand doit-on effectuer ces tests ?

Ils sont généralement réalisés entre la 15e et la 20e semaine de grossesse.
Grossesse Sérum maternel Dépistage prénatal
#3

Comment les résultats sont-ils interprétés ?

Les résultats sont comparés à des valeurs de référence pour évaluer le risque d'anomalies.
Interprétation des tests Anomalies congénitales Dépistage prénatal
#4

Quels risques peuvent être détectés ?

Les tests peuvent détecter des risques de trisomie 21, trisomie 18 et anomalies du tube neural.
Trisomie 21 Anomalies congénitales Dépistage prénatal
#5

Les tests sont-ils obligatoires ?

Non, ils sont recommandés mais le choix d'effectuer le test appartient à la patiente.
Consentement éclairé Dépistage prénatal Grossesse

Symptômes 2

#1

Quels symptômes indiquent un besoin de dépistage ?

Il n'y a pas de symptômes spécifiques, le dépistage est préventif.
Dépistage prénatal Anomalies congénitales Grossesse
#2

Les tests révèlent-ils des symptômes chez le fœtus ?

Non, ils évaluent le risque, mais ne montrent pas de symptômes directs.
Dépistage prénatal Fœtus Anomalies congénitales

Prévention 2

#1

Comment peut-on réduire les risques d'anomalies ?

Une bonne nutrition, des suppléments d'acide folique et des soins prénatals réguliers aident.
Acide folique Nutrition Soins prénatals
#2

Le dépistage peut-il prévenir les anomalies ?

Non, il permet seulement d'évaluer le risque et de planifier des soins appropriés.
Dépistage prénatal Anomalies congénitales Prévention

Traitements 2

#1

Que faire si le test est positif ?

Un suivi avec des tests supplémentaires comme l'amniocentèse peut être recommandé.
Amniocentèse Dépistage prénatal Anomalies congénitales
#2

Y a-t-il des traitements préventifs ?

Il n'existe pas de traitement préventif, mais un suivi médical est essentiel.
Suivi médical Dépistage prénatal Grossesse

Complications 2

#1

Quelles complications peuvent survenir après un test positif ?

Des complications psychologiques peuvent survenir, comme l'anxiété ou le stress.
Anxiété Stress Dépistage prénatal
#2

Les tests peuvent-ils causer des complications ?

Les tests sanguins sont généralement sûrs, mais des complications peuvent survenir lors d'autres tests.
Complications Dépistage prénatal Amniocentèse

Facteurs de risque 2

#1

Quels sont les facteurs de risque pour les anomalies ?

L'âge maternel avancé, des antécédents familiaux et certaines conditions médicales augmentent le risque.
Âge maternel Antécédents familiaux Anomalies congénitales
#2

Le mode de vie influence-t-il les résultats ?

Oui, des facteurs comme le tabagisme, l'alcool et la nutrition peuvent influencer les résultats.
Tabagisme Nutrition Dépistage prénatal
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Dr Olivier Menir

Contenu validé par Dr Olivier Menir

Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale


Validation scientifique effectuée le 18/04/2025

Contenu vérifié selon les dernières recommandations médicales

Auteurs principaux

K H Nicolaides

5 publications dans cette catégorie

Affiliations :
  • Fetal Medicine Research Institute, King's College Hospital, London, UK.
Publications dans "Tests de dépistage du sérum maternel" :

Maurizio Guida

2 publications dans cette catégorie

Affiliations :
  • Theoreo srl, Montecorvino Pugliano, Salerno, Italy; Department of Neurosciences and Reproductive and Dentistry Sciences, University of Naples Federico II, Naples, Italy.

Ron Maymon

2 publications dans cette catégorie

Affiliations :
  • The Yitzhak Shamir Medical Center (Formerly Assaf Harofeh Medical Center), Institute of Ultrasound, Zerifin, Israel.
  • Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

Hamutal Meiri

2 publications dans cette catégorie

Affiliations :
  • ASPRE Project, Telemarpe Ltd, Tel Aviv, Israel.
  • Hy-Laboratories Ltd, Rehovot, Israel.

N Sokratous

2 publications dans cette catégorie

Affiliations :
  • Fetal Medicine Research Institute, King's College Hospital, London, UK.
Publications dans "Tests de dépistage du sérum maternel" :

A Syngelaki

2 publications dans cette catégorie

Affiliations :
  • Fetal Medicine Research Institute, King's College Hospital, London, UK.
  • Institute of Women and Children's Health, School of Life Course and Population Sciences, King's College London, London, UK.
Publications dans "Tests de dépistage du sérum maternel" :

A Wright

2 publications dans cette catégorie

Affiliations :
  • Institute of Health Research, University of Exeter, Exeter, UK.
Publications dans "Tests de dépistage du sérum maternel" :

S Galeva

2 publications dans cette catégorie

Affiliations :
  • Fetal Medicine Research Institute, King's College Hospital, London, UK.
  • Department of Fetal Medicine, Medway Maritime Hospital, Kent, UK.
Publications dans "Tests de dépistage du sérum maternel" :

M M Gil

2 publications dans cette catégorie

Affiliations :
  • Fetal Medicine Research Institute, King's College Hospital, London, UK.
  • School of Health Sciences, Universidad Francisco de Vitoria, Pozuelo de Alarcón, Madrid, Spain.
  • Obstetrics and Gynecology Department, Hospital Universitario de Torrejón, Torrejón de Ardoz, Madrid, Spain.
Publications dans "Tests de dépistage du sérum maternel" :

L Konstantinidou

2 publications dans cette catégorie

Affiliations :
  • Fetal Medicine Research Institute, King's College Hospital, London, UK.
Publications dans "Tests de dépistage du sérum maternel" :

R Akolekar

2 publications dans cette catégorie

Affiliations :
  • Department of Fetal Medicine, Medway Maritime Hospital, Kent, UK.
  • Institute of Medical Sciences, Canterbury Christ Church University, Chatham, UK.
Publications dans "Tests de dépistage du sérum maternel" :

Cecilie S Uldbjerg

2 publications dans cette catégorie

Affiliations :
  • Department of Growth and Reproduction, Copenhagen University Hospital-Rigshospitalet, Copenhagen, Denmark.
  • International Centre for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Denmark.

Russ Hauser

2 publications dans cette catégorie

Affiliations :
  • Department of Environmental Health, Harvard T.H. Chan School of Public Health, Harvard University, Boston, Massachusetts, United States of America.

Anders Juul

2 publications dans cette catégorie

Affiliations :
  • Department of Growth and Reproduction, Copenhagen University Hospital-Rigshospitalet, Copenhagen, Denmark.
  • International Centre for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Denmark.
  • Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.

Elvira V Bräuner

2 publications dans cette catégorie

Affiliations :
  • Department of Growth and Reproduction, Copenhagen University Hospital-Rigshospitalet, Copenhagen, Denmark.
  • International Centre for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Rigshospitalet, University of Copenhagen, Denmark.

Jacques C Jani

2 publications dans cette catégorie

Affiliations :
  • Department of Obstetrics and Gynecology, University Hospital Brugmann, Université Libre de Bruxelles, Brussels, Belgium.
Publications dans "Tests de dépistage du sérum maternel" :

Xin Wang

2 publications dans cette catégorie

Affiliations :
  • Prenatal Diagnostic Center, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing, 100026 China.

Seung Ah Choe

2 publications dans cette catégorie

Affiliations :
  • Department of Preventive Medicine, Korea University College of Medicine, Seoul, Korea.

Hyun Joo Seol

2 publications dans cette catégorie

Affiliations :
  • Department of Obstetrics and Gynecology, Kyung Hee University Hospital at Gangdong, Kyung Hee University College of Medicine, Seoul, Korea.

Sources (10000 au total)

A case-control study of infections caused by

Infections caused by antimicrobial-resistant bacteria are a significant cause of death worldwide, and carbapenemase-producing bacteria are the principal agents. New Delhi metallo-beta-lactamase-1 prod... A retrospective case-control study with patients hospitalized from January 2012 to February 2018 at the Hospital Civil de Guadalajara "Fray Antonio Alcalde" was designed. During this period, 139 patie... One hundred and thirty-nine case patients with a KP-NDM-1 isolate and 486 control patients were analyzed. In the case group, acute renal failure was a significant comorbidity, hospitalization days wer... In this study, the previous use of antibiotics, the use of a urinary catheter, the use of a central venous catheter, the use of mechanical ventilation, and ICU stay were shown to be predictors of infe...

Errors in Surgery: A Case Control Study.

While errors can harm patients they remain poorly studied. This study characterized errors in the care of surgical patients and examined the association of errors with morbidity and mortality.... Errors have been reported to cause <10% or >60% of adverse events. Such discordant results underscore the need for further exploration of the relationship between error and adverse events.... Patients with operations performed at a single institution and abstracted into the American College of Surgeons National Surgical Quality Improvement Program from January 1, 2018, to December 31, 2018... Of 1899 patients, 170 were defined as cases who experienced a morbidity or mortality. The majority of cases (n=93; 55%) had at least 1 error; of the 329 matched control patients, 112 had at least 1 er... Errors in surgical care were associated with postoperative morbidity. Reducing errors requires measurement of errors....

Iron status in women with infertility and controls: a case-control study.

Iron deficiency is a common problem in subfertile women. The influence of iron status on unexplained infertility is unknown.... In a case-control study, 36 women with unexplained infertility and 36 healthy non-infertile controls were included. Parameters of iron status including serum ferritin and a serum ferritin <30 µg/dL se... Women with unexplained infertility demonstrated a lower transferrin saturation (median 17.3%, IQR 12.7-25.2 versus 23.9%, IQR 15.4-31.6;... Ferritin levels <30µg/L were associated with unexplained infertility and might be screened in the future. Further studies with a focus on iron deficiency and iron treatment on women with unexplained i...

Sleeve Gastrectomy in Septuagenarians: a Case-Control Study.

There are few studies published referring to bariatric surgery in patients older than 70 years. The aim of this study is to evaluate whether there are benefits to performing sleeve gastrectomy (SG) in... Data were retrospectively collected from a Private Clinic's electronic medical records of patients undergoing SG between June 2017 and September 2020. Inclusion criteria were patients older than 70 ye... Fifty patients were included in the study. Both groups were similar regarding gender, weight, BMI, and presence of DM. The 30-day morbidity and mortality were similar between the groups. The patients ... The sleeve gastrectomy surgery performed in patients over 70 years of age is safe. The early results suggest similar benefits regarding weight loss and improvement of comorbidities to those having SG ...

Diverticulitis Familiality: A Statewide Case-Control Study.

The etiology of diverticulitis is multifactorial and poorly understood. We estimated the familiality of diverticulitis using the Utah Population Database, a statewide database linking medical records ... We identified patients with diverticulitis diagnosed between 1998 and 2018 and age- and sex-matched controls in the Utah Population Database. Risk of diverticulitis in family members of patients and c... The study population included 9,563 diverticulitis patients (with 229,647 relatives) and 10,588 controls (with 265,693 relatives). Relatives of patients were more likely to develop diverticulitis (inc... Our results indicate that the first-, second-, and third-degree relatives of diverticulitis patients are at elevated risk of developing diverticulitis. This information may aid surgeons in counseling ...

Thrombocytosis in patients with spondyloarthritis: a case-control study.

This study aimed to investigate the clinical and laboratory as well as radiological features of spondyloarthritis (SpA) patients with thrombocytosis and to explore risk factor for thrombocytosis in Sp... A total of 145 patients with SpA were included in this study, and non-thrombocytosis was identified in 76 patients while thrombocytosis was found in 69 patients, 38 out of the 69 patients received ant... The proportion of hip involvement (60.86% vs 36.84%, p = 0.004), bath ankylosing spondylitis disease activity index score (4.24 ± 0.55 vs 3.69 ± 0.67, p < 0.001), erythrocyte sedimentation rate (62.22... SpA patients with thrombocytosis have a higher proportion of hip involvement and disease activity compared to non-thrombocytosis SpA patients. The potential risk factors for thrombocytosis in SPA pati...

Vestibulodynia and the Vaginal Microbiome: A Case-Control Study.

Recent studies of the vaginal microbiome have led to a better understanding of the microbiota and interactions with the host environment, however the role of the vaginal microbiome in vestibulodynia r... This study aims to investigate and examine differences in the bacterial and fungal microbiome among patients with vestibulodynia and healthy controls.... A case-control study was conducted examining the vaginal microbiome of 29 patients with vestibulodynia and 26 controls through Stony Brook University Obstetrics and Gynecology ambulatory clinic. Exclu... Principal component analysis (PCA) and linear discriminant analysis effect size (LefSe) were used to identify differences in relative abundance of operational taxonomic units (OTUs) for the vaginal mi... Lactobacillus species were dominant amongst both cases and controls. PCA of 16S and ITS OTUs did not show significant differences in microbiome composition between vestibulodynia patients and controls... Additional studies are needed to further assess the clinical significance of these findings.... Strengths of this study include ITS amplicon sequence analysis for fungal species diversity. Limitations of this study include small sample size and lack of racial diversity.... Our study did not find significant differences in composition or diversity between the vaginal microbiomes of cases of vestibulodynia and controls; however, the data suggests differences in abundance ...

Bladder cancer with pioglitazone: A case-control study.

Varied reports suggest a contentious relationship of bladder malignancy with pioglitazone in patients with type 2 diabetes.... To study an association (prevalence and predictors) of bladder malignancy with pioglitazone therapy in Asian-Indian type 2 diabetes patients.... In this observational multicenter study, type 2 diabetic patients attending out-patient diabetes-clinic were evaluated. A detailed history of anti-diabetic medication, dose, duration, pioglitazone usa... A total of 8000 patients were screened out of which 1560 were excluded. Among 6440 included patients, 1056 (16.3%) patients were in group A and 5384 (83.6%) group B. Patients on pioglitazone were olde... Pioglitazone use in Asian-Indians is not associated with an increased bladder cancer risk. However, pioglitazone should be restricted in individuals with history of hematuria. Age more than 58 years i...

HTRA1 methylation in peripheral blood as a potential marker for the preclinical detection of stroke: a case-control study and a prospective nested case-control study.

Stroke is the leading cause of mortality in China. DNA methylation has essential roles in multiple diseases, but its association with stroke was barely studied. We hereby explored the association betw... The association was discovered in a hospital-based case-control study (cases/controls = 190:190) and further validated in a prospective nested case-control study including 139 cases who developed stro... In our study, altered HTRA1 methylation was associated with stroke at clinical and preclinical stages and thus may provide a potential biomarker in the blood for the risk evaluation and preclinical de...