Titre : Protéines associées aux CRISPR

Protéines associées aux CRISPR : Questions médicales fréquentes

Termes MeSH sélectionnés :

Exercise
{ "@context": "https://schema.org", "@graph": [ { "@type": "MedicalWebPage", "name": "Protéines associées aux CRISPR : Questions médicales les plus fréquentes", "headline": "Protéines associées aux CRISPR : Comprendre les symptômes, diagnostics et traitements", "description": "Guide complet et accessible sur les Protéines associées aux CRISPR : explications, diagnostics, traitements et prévention. Information médicale validée destinée aux patients.", "datePublished": "2024-05-15", "dateModified": "2025-02-09", "inLanguage": "fr", "medicalAudience": [ { "@type": "MedicalAudience", "name": "Grand public", "audienceType": "Patient", "healthCondition": { "@type": "MedicalCondition", "name": "Protéines associées aux CRISPR" }, "suggestedMinAge": 18, "suggestedGender": "unisex" }, { "@type": "MedicalAudience", "name": "Médecins", "audienceType": "Physician", "geographicArea": { "@type": "AdministrativeArea", "name": "France" } }, { "@type": "MedicalAudience", "name": "Chercheurs", "audienceType": "Researcher", "geographicArea": { "@type": "AdministrativeArea", "name": "International" } } ], "reviewedBy": { "@type": "Person", "name": "Dr Olivier Menir", "jobTitle": "Expert en Médecine", "description": "Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale", "url": "/static/pages/docteur-olivier-menir.html", "alumniOf": { "@type": "EducationalOrganization", "name": "Université Paris Descartes" } }, "isPartOf": { "@type": "MedicalWebPage", "name": "Protéines", "url": "https://questionsmedicales.fr/mesh/D011506", "about": { "@type": "MedicalCondition", "name": "Protéines", "code": { "@type": "MedicalCode", "code": "D011506", "codingSystem": "MeSH" }, "identifier": { "@type": "PropertyValue", "propertyID": "MeSH Tree", "value": "D12.776" } } }, "hasPart": [ { "@type": "MedicalWebPage", "name": "Protéine-9 associée à CRISPR", "alternateName": "CRISPR-Associated Protein 9", "url": "https://questionsmedicales.fr/mesh/D000076987", "about": { "@type": "MedicalCondition", "name": "Protéine-9 associée à CRISPR", "code": { "@type": "MedicalCode", "code": "D000076987", "codingSystem": "MeSH" }, "identifier": { "@type": "PropertyValue", "propertyID": "MeSH Tree", "value": "D12.776.212.500" } } } ], "about": { "@type": "MedicalCondition", "name": "Protéines associées aux CRISPR", "alternateName": "CRISPR-Associated Proteins", "code": { "@type": "MedicalCode", "code": "D064130", "codingSystem": "MeSH" } }, "author": [ { "@type": "Person", "name": "Yi Zhang", "url": "https://questionsmedicales.fr/author/Yi%20Zhang", "affiliation": { "@type": "Organization", "name": "Beijing Advanced Innovation Center for Soft Matter Science and Engineering, Beijing Key Laboratory of Bioprocess, State Key Laboratory of Chemical Resource Engineering, College of Life Science and Technology, Beijing University of Chemical Technology, Beijing, China." } }, { "@type": "Person", "name": "Yue Feng", "url": "https://questionsmedicales.fr/author/Yue%20Feng", "affiliation": { "@type": "Organization", "name": "Beijing Advanced Innovation Center for Soft Matter Science and Engineering, Beijing Key Laboratory of Bioprocess, State Key Laboratory of Chemical Resource Engineering, College of Life Science and Technology, Beijing University of Chemical Technology, Beijing, China. Electronic address: fengyue@mail.buct.edu.cn." } }, { "@type": "Person", "name": "Joseph Bondy-Denomy", "url": "https://questionsmedicales.fr/author/Joseph%20Bondy-Denomy", "affiliation": { "@type": "Organization", "name": "Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA 94143, USA; Quantitative Biosciences Institute, University of California, San Francisco, San Francisco, CA 94143, USA." } }, { "@type": "Person", "name": "Alan R Davidson", "url": "https://questionsmedicales.fr/author/Alan%20R%20Davidson", "affiliation": { "@type": "Organization", "name": "Department of Molecular Genetics, University of Toronto, Toronto, ON M5S 1A8, Canada; Department of Biochemistry, University of Toronto, Toronto, ON M5S 1A8, Canada. Electronic address: alan.davidson@utoronto.ca." } }, { "@type": "Person", "name": "Xu Peng", "url": "https://questionsmedicales.fr/author/Xu%20Peng", "affiliation": { "@type": "Organization", "name": "Department of Biology, University of Copenhagen, Copenhagen N, Denmark. Electronic address: peng@bio.ku.dk." } } ], "citation": [ { "@type": "ScholarlyArticle", "name": "The intensity of a resistance exercise session can be quantified by the work rate of exercise.", "datePublished": "2023-10-05", "url": "https://questionsmedicales.fr/article/37797065", "identifier": { "@type": "PropertyValue", "propertyID": "DOI", "value": "10.1371/journal.pone.0291857" } }, { "@type": "ScholarlyArticle", "name": "Exercise to Treat Hypertension: Late Breaking News on Exercise Prescriptions That FITT.", "datePublished": "2022-08-01", "url": "https://questionsmedicales.fr/article/35946847", "identifier": { "@type": "PropertyValue", "propertyID": "DOI", "value": "10.1249/JSR.0000000000000983" } }, { "@type": "ScholarlyArticle", "name": "Intelligent Estimation of Exercise Induced Energy Expenditure Including Excess Post-Exercise Oxygen Consumption (EPOC) with Different Exercise Intensity.", "datePublished": "2023-11-16", "url": "https://questionsmedicales.fr/article/38005621", "identifier": { "@type": "PropertyValue", "propertyID": "DOI", "value": "10.3390/s23229235" } }, { "@type": "ScholarlyArticle", "name": "Ischemic Preconditioning, But Not Priming Exercise, Improves Exercise Performance in Trained Rock Climbers.", "datePublished": "2023-08-22", "url": "https://questionsmedicales.fr/article/37607294", "identifier": { "@type": "PropertyValue", "propertyID": "DOI", "value": "10.1519/JSC.0000000000004565" } }, { "@type": "ScholarlyArticle", "name": "Outcomes following supervised exercise and home-based exercise for patients with intermittent claudication.", "datePublished": "2022-10-04", "url": "https://questionsmedicales.fr/article/36435597", "identifier": { "@type": "PropertyValue", "propertyID": "DOI", "value": "10.1016/j.jvn.2022.09.006" } } ], "breadcrumb": { "@type": "BreadcrumbList", "itemListElement": [ { "@type": "ListItem", "position": 1, "name": "questionsmedicales.fr", "item": "https://questionsmedicales.fr" }, { "@type": "ListItem", "position": 2, "name": "Acides aminés, peptides et protéines", "item": "https://questionsmedicales.fr/mesh/D000602" }, { "@type": "ListItem", "position": 3, "name": "Protéines", "item": "https://questionsmedicales.fr/mesh/D011506" }, { "@type": "ListItem", "position": 4, "name": "Protéines associées aux CRISPR", "item": "https://questionsmedicales.fr/mesh/D064130" } ] } }, { "@type": "MedicalWebPage", "name": "Article complet : Protéines associées aux CRISPR - Questions et réponses", "headline": "Questions et réponses médicales fréquentes sur Protéines associées aux CRISPR", "description": "Une compilation de questions et réponses structurées, validées par des experts médicaux.", "datePublished": "2025-05-07", "inLanguage": "fr", "hasPart": [ { "@type": "MedicalWebPage", "name": "Diagnostic", "headline": "Diagnostic sur Protéines associées aux CRISPR", "description": "Comment identifier les protéines CRISPR dans un échantillon ?\nQuels tests sont utilisés pour détecter les protéines associées ?\nPeut-on détecter les protéines CRISPR par imagerie ?\nQuels marqueurs sont spécifiques aux protéines CRISPR ?\nComment évaluer l'activité des protéines CRISPR ?", "url": "https://questionsmedicales.fr/mesh/D064130?mesh_terms=Exercise&page=2#section-diagnostic" }, { "@type": "MedicalWebPage", "name": "Symptômes", "headline": "Symptômes sur Protéines associées aux CRISPR", "description": "Quels symptômes sont liés à des dysfonctionnements CRISPR ?\nLes protéines CRISPR causent-elles des effets secondaires ?\nComment les protéines CRISPR affectent-elles la santé ?\nY a-t-il des symptômes d'allergie aux protéines CRISPR ?\nLes protéines CRISPR peuvent-elles provoquer des cancers ?", "url": "https://questionsmedicales.fr/mesh/D064130?mesh_terms=Exercise&page=2#section-symptômes" }, { "@type": "MedicalWebPage", "name": "Prévention", "headline": "Prévention sur Protéines associées aux CRISPR", "description": "Comment prévenir les maladies liées aux protéines CRISPR ?\nLes vaccins peuvent-ils intégrer CRISPR ?\nY a-t-il des mesures préventives pour les traitements CRISPR ?\nComment éduquer sur les risques des CRISPR ?\nLes tests génétiques peuvent-ils prévenir des maladies ?", "url": "https://questionsmedicales.fr/mesh/D064130?mesh_terms=Exercise&page=2#section-prévention" }, { "@type": "MedicalWebPage", "name": "Traitements", "headline": "Traitements sur Protéines associées aux CRISPR", "description": "Comment les protéines CRISPR sont-elles utilisées en thérapie ?\nQuels types de maladies peuvent être traités avec CRISPR ?\nY a-t-il des traitements en cours avec CRISPR ?\nQuels sont les défis des traitements CRISPR ?\nCRISPR peut-il être utilisé pour des maladies infectieuses ?", "url": "https://questionsmedicales.fr/mesh/D064130?mesh_terms=Exercise&page=2#section-traitements" }, { "@type": "MedicalWebPage", "name": "Complications", "headline": "Complications sur Protéines associées aux CRISPR", "description": "Quelles complications peuvent survenir avec CRISPR ?\nComment gérer les complications des traitements CRISPR ?\nLes complications sont-elles fréquentes avec CRISPR ?\nQuelles sont les conséquences des effets hors cible ?\nLes complications peuvent-elles être réversibles ?", "url": "https://questionsmedicales.fr/mesh/D064130?mesh_terms=Exercise&page=2#section-complications" }, { "@type": "MedicalWebPage", "name": "Facteurs de risque", "headline": "Facteurs de risque sur Protéines associées aux CRISPR", "description": "Quels sont les facteurs de risque pour les traitements CRISPR ?\nLes mutations génétiques augmentent-elles les risques ?\nL'environnement influence-t-il les risques liés à CRISPR ?\nLes antécédents familiaux sont-ils un facteur de risque ?\nLes traitements antérieurs affectent-ils les risques ?", "url": "https://questionsmedicales.fr/mesh/D064130?mesh_terms=Exercise&page=2#section-facteurs de risque" } ] }, { "@type": "FAQPage", "mainEntity": [ { "@type": "Question", "name": "Comment identifier les protéines CRISPR dans un échantillon ?", "position": 1, "acceptedAnswer": { "@type": "Answer", "text": "L'identification se fait par des techniques comme la PCR et le séquençage." } }, { "@type": "Question", "name": "Quels tests sont utilisés pour détecter les protéines associées ?", "position": 2, "acceptedAnswer": { "@type": "Answer", "text": "Des tests d'immunobuvardage et de chromatographie peuvent être utilisés." } }, { "@type": "Question", "name": "Peut-on détecter les protéines CRISPR par imagerie ?", "position": 3, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des techniques comme la microscopie à fluorescence peuvent être utilisées." } }, { "@type": "Question", "name": "Quels marqueurs sont spécifiques aux protéines CRISPR ?", "position": 4, "acceptedAnswer": { "@type": "Answer", "text": "Les marqueurs spécifiques incluent les séquences génétiques uniques des gènes cas." } }, { "@type": "Question", "name": "Comment évaluer l'activité des protéines CRISPR ?", "position": 5, "acceptedAnswer": { "@type": "Answer", "text": "L'activité peut être évaluée par des tests de coupure d'ADN et d'édition génétique." } }, { "@type": "Question", "name": "Quels symptômes sont liés à des dysfonctionnements CRISPR ?", "position": 6, "acceptedAnswer": { "@type": "Answer", "text": "Des symptômes peuvent inclure des anomalies génétiques et des maladies héréditaires." } }, { "@type": "Question", "name": "Les protéines CRISPR causent-elles des effets secondaires ?", "position": 7, "acceptedAnswer": { "@type": "Answer", "text": "Des effets secondaires peuvent survenir, comme des réponses immunitaires indésirables." } }, { "@type": "Question", "name": "Comment les protéines CRISPR affectent-elles la santé ?", "position": 8, "acceptedAnswer": { "@type": "Answer", "text": "Elles peuvent influencer la santé en modifiant des gènes liés à des maladies." } }, { "@type": "Question", "name": "Y a-t-il des symptômes d'allergie aux protéines CRISPR ?", "position": 9, "acceptedAnswer": { "@type": "Answer", "text": "Des réactions allergiques peuvent survenir, mais elles sont rares et peu documentées." } }, { "@type": "Question", "name": "Les protéines CRISPR peuvent-elles provoquer des cancers ?", "position": 10, "acceptedAnswer": { "@type": "Answer", "text": "Des modifications génétiques inappropriées peuvent augmenter le risque de cancer." } }, { "@type": "Question", "name": "Comment prévenir les maladies liées aux protéines CRISPR ?", "position": 11, "acceptedAnswer": { "@type": "Answer", "text": "La prévention passe par des dépistages génétiques et des conseils en génétique." } }, { "@type": "Question", "name": "Les vaccins peuvent-ils intégrer CRISPR ?", "position": 12, "acceptedAnswer": { "@type": "Answer", "text": "Des recherches explorent l'utilisation de CRISPR pour améliorer les vaccins existants." } }, { "@type": "Question", "name": "Y a-t-il des mesures préventives pour les traitements CRISPR ?", "position": 13, "acceptedAnswer": { "@type": "Answer", "text": "Des mesures incluent le suivi des effets secondaires et l'évaluation des risques." } }, { "@type": "Question", "name": "Comment éduquer sur les risques des CRISPR ?", "position": 14, "acceptedAnswer": { "@type": "Answer", "text": "L'éducation passe par des campagnes d'information et des ressources en santé publique." } }, { "@type": "Question", "name": "Les tests génétiques peuvent-ils prévenir des maladies ?", "position": 15, "acceptedAnswer": { "@type": "Answer", "text": "Oui, les tests génétiques permettent d'identifier les risques et de prendre des mesures." } }, { "@type": "Question", "name": "Comment les protéines CRISPR sont-elles utilisées en thérapie ?", "position": 16, "acceptedAnswer": { "@type": "Answer", "text": "Elles sont utilisées pour corriger des mutations génétiques dans des thérapies géniques." } }, { "@type": "Question", "name": "Quels types de maladies peuvent être traités avec CRISPR ?", "position": 17, "acceptedAnswer": { "@type": "Answer", "text": "CRISPR peut traiter des maladies génétiques, des cancers et des infections virales." } }, { "@type": "Question", "name": "Y a-t-il des traitements en cours avec CRISPR ?", "position": 18, "acceptedAnswer": { "@type": "Answer", "text": "Oui, plusieurs essais cliniques explorent l'utilisation de CRISPR pour diverses maladies." } }, { "@type": "Question", "name": "Quels sont les défis des traitements CRISPR ?", "position": 19, "acceptedAnswer": { "@type": "Answer", "text": "Les défis incluent la précision de l'édition et les effets hors cible potentiels." } }, { "@type": "Question", "name": "CRISPR peut-il être utilisé pour des maladies infectieuses ?", "position": 20, "acceptedAnswer": { "@type": "Answer", "text": "Oui, CRISPR est exploré pour cibler et éliminer des virus dans des infections." } }, { "@type": "Question", "name": "Quelles complications peuvent survenir avec CRISPR ?", "position": 21, "acceptedAnswer": { "@type": "Answer", "text": "Les complications incluent des modifications hors cible et des réactions immunitaires." } }, { "@type": "Question", "name": "Comment gérer les complications des traitements CRISPR ?", "position": 22, "acceptedAnswer": { "@type": "Answer", "text": "La gestion implique un suivi médical rigoureux et des ajustements de traitement." } }, { "@type": "Question", "name": "Les complications sont-elles fréquentes avec CRISPR ?", "position": 23, "acceptedAnswer": { "@type": "Answer", "text": "Les complications sont rares mais peuvent survenir, nécessitant une surveillance." } }, { "@type": "Question", "name": "Quelles sont les conséquences des effets hors cible ?", "position": 24, "acceptedAnswer": { "@type": "Answer", "text": "Les effets hors cible peuvent entraîner des mutations indésirables et des maladies." } }, { "@type": "Question", "name": "Les complications peuvent-elles être réversibles ?", "position": 25, "acceptedAnswer": { "@type": "Answer", "text": "Certaines complications peuvent être réversibles, mais cela dépend du cas spécifique." } }, { "@type": "Question", "name": "Quels sont les facteurs de risque pour les traitements CRISPR ?", "position": 26, "acceptedAnswer": { "@type": "Answer", "text": "Les facteurs incluent l'âge, l'état de santé et les antécédents médicaux." } }, { "@type": "Question", "name": "Les mutations génétiques augmentent-elles les risques ?", "position": 27, "acceptedAnswer": { "@type": "Answer", "text": "Oui, certaines mutations peuvent accroître le risque de complications avec CRISPR." } }, { "@type": "Question", "name": "L'environnement influence-t-il les risques liés à CRISPR ?", "position": 28, "acceptedAnswer": { "@type": "Answer", "text": "L'environnement peut jouer un rôle dans l'expression des gènes modifiés." } }, { "@type": "Question", "name": "Les antécédents familiaux sont-ils un facteur de risque ?", "position": 29, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des antécédents familiaux de maladies génétiques peuvent augmenter les risques." } }, { "@type": "Question", "name": "Les traitements antérieurs affectent-ils les risques ?", "position": 30, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des traitements antérieurs peuvent influencer la réponse aux thérapies CRISPR." } } ] } ] }

Sources (10000 au total)

The intensity of a resistance exercise session can be quantified by the work rate of exercise.

Athletes regularly perform resistance training, yet it is unknown how best to monitor its intensity. This study compared different resistance exercise intensity metrics to determine their sensitivity ... Following baseline testing for 10- and 3-repetition maximum (RM; squat and bench press), fourteen trained participants completed four volume-matched protocols in a randomised order: 3x10 with 85% 10RM... Internal intensity and work-rate metrics were highest for 3x1060s, followed by 3x10180s, 8x3120s and 8x3300s (p≤0.027). TI and II were higher for 8x3 than 3x10 protocols (p<0.001), but not different w... Work rate corroborated objective internal intensity metrics during resistance exercise, with the highest work rate session (3x1060s) also eliciting greater RPE scores than other protocols. In contrast...

Outcomes following supervised exercise and home-based exercise for patients with intermittent claudication.

Intermittent claudication (IC) is the most common symptom of peripheral arterial disease (PAD) which presents as a consequence of muscle ischaemia resulting from the atherosclerotic obstruction to art... Retrospective data were analysed to examine walking and ABPI outcomes for participants who completed a 12-week course of supervised or home-based exercise. All participants had a history of IC.... 46 participants (mean age 69±11 years; 76% male; 29% current smokers) referred for exercise were assessed, completed a 12-week course of exercise (home-based or supervised) and subsequently attended f... A 12-week course of supervised exercise results in significantly greater walking distance outcomes (COD and PWD) than unmonitored home-based exercise. In contrast with previous findings (Lane et al. 2... A 12-week programme of exercise favourably influenced walking and ABPI outcomes for patients with IC. Both home-based exercise and supervised individualised exercise increased walking distances, but t...

Physiological adaptations following vigorous exercise and moderate exercise with superimposed electrical stimulation.

Neuromuscular electrical stimulation (NMES) induces involuntary muscle contraction, preferentially promotes anaerobic metabolism, and is applicable for increasing exercise intensity. This study aimed ... Eight participants trained with a cycling ergometer at 100% of the ventilatory threshold (VT) (73.3% of peak oxygen consumption) (VOL), and another nine participants trained with the cycling ergometer... Rating of perceived exertion (RPE) in VOLES (12.00 ± 1.50) was significantly lower than in VOL (14.88 ± 1.81) (p < 0.05) during training sessions. Peak power output during the exercise tolerance test ... Our results suggest that both superimposing subtetanic NMES onto moderate-intensity voluntary exercise and vigorous voluntary intensity exercise induce the improvement in cardiovascular and metabolic ...

Relationship among subjective exercise experience, exercise behavior, and trait anxiety in adolescents.

To investigate the influence of subjective exercise experience on adolescent trait anxiety and to reveal the mediating effect of exercise behavior.... Using the Subjective Exercise Experience Scale (SEES), Physical Exercise Rating Scale (PARS-3), and Trait Anxiety Inventory (T-AI), a questionnaire survey was conducted among 500 adolescents in Southw... 1) Among adolescents, the exercise behavior of boys was significantly higher than that of girls (p < 0.05), and the subjective exercise experience of students aged 9 to 12 was significantly higher tha... The good subjective exercise experience not only has direct benefits for improving trait anxiety in adolescents but also helps to improve their exercise behavior, enrich daily physical exercise activi...