Oui, l'âge avancé peut augmenter le risque d'anomalies chromosomiques.
ÂgeAnomalies chromosomiques
#3
Le mode de vie affecte-t-il le risque ?
Un mode de vie malsain peut augmenter le risque d'anomalies génétiques.
Mode de vieAnomalies génétiques
#4
Y a-t-il des antécédents familiaux à considérer ?
Oui, des antécédents familiaux d'anomalies peuvent augmenter le risque.
Antécédents familiauxRisque
#5
Les infections pendant la grossesse sont-elles un facteur de risque ?
Certaines infections pendant la grossesse peuvent affecter le développement chromosomique.
InfectionsGrossesse
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"acceptedAnswer": {
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"@type": "Question",
"name": "Des dépistages réguliers sont-ils recommandés ?",
"position": 13,
"acceptedAnswer": {
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"name": "L'alimentation joue-t-elle un rôle dans la prévention ?",
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"@type": "Question",
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"position": 15,
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"@type": "Question",
"name": "Quels traitements sont disponibles pour les anomalies du Composant-7 ?",
"position": 16,
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"@type": "Answer",
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"position": 17,
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"@type": "Question",
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"position": 18,
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"@type": "Question",
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"position": 19,
"acceptedAnswer": {
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"position": 20,
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"@type": "Question",
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"@type": "Question",
"name": "Les anomalies peuvent-elles affecter la fertilité ?",
"position": 22,
"acceptedAnswer": {
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"@type": "Question",
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"position": 23,
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"@type": "Answer",
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"@type": "Answer",
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"@type": "Question",
"name": "Quels sont les facteurs de risque pour les anomalies du Composant-7 ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
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"@type": "Question",
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"position": 27,
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"@type": "Question",
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"position": 28,
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"@type": "Question",
"name": "Y a-t-il des antécédents familiaux à considérer ?",
"position": 29,
"acceptedAnswer": {
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"text": "Oui, des antécédents familiaux d'anomalies peuvent augmenter le risque."
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"@type": "Question",
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Department of Hepatic Surgery and Liver transplantation Center of the Third Affiliated Hospital, Organ Transplantation Institute, Sun Yat-sen University, Organ Transplantation Research Center of Guangdong Province, 600# Tianhe Road, Guangzhou, 510630, China.
Publications dans "Composant-7 du complexe de maintenance des minichromosomes" :
Department of Hepatic Surgery and Liver transplantation Center of the Third Affiliated Hospital, Organ Transplantation Institute, Sun Yat-sen University, Organ Transplantation Research Center of Guangdong Province, 600# Tianhe Road, Guangzhou, 510630, China.
Publications dans "Composant-7 du complexe de maintenance des minichromosomes" :
Department of Hepatic Surgery and Liver transplantation Center of the Third Affiliated Hospital, Organ Transplantation Institute, Sun Yat-sen University, Organ Transplantation Research Center of Guangdong Province, 600# Tianhe Road, Guangzhou, 510630, China.
Publications dans "Composant-7 du complexe de maintenance des minichromosomes" :
Department of Hepatic Surgery and Liver transplantation Center of the Third Affiliated Hospital, Organ Transplantation Institute, Sun Yat-sen University, Organ Transplantation Research Center of Guangdong Province, 600# Tianhe Road, Guangzhou, 510630, China.
Publications dans "Composant-7 du complexe de maintenance des minichromosomes" :
Department of Hepatic Surgery and Liver transplantation Center of the Third Affiliated Hospital, Organ Transplantation Institute, Sun Yat-sen University, Organ Transplantation Research Center of Guangdong Province, 600# Tianhe Road, Guangzhou, 510630, China. zhjianw2@mail.sysu.edu.cn.
Publications dans "Composant-7 du complexe de maintenance des minichromosomes" :
Department of Medical Oncology of the Eastern Hospital, The First Affiliated Hospital of Sun Yat-sen University, Zhongshan Er Road, Guangzhou, 510080, China. drliheping@163.com.
Publications dans "Composant-7 du complexe de maintenance des minichromosomes" :
Department of Hepatic Surgery and Liver transplantation Center of the Third Affiliated Hospital, Organ Transplantation Institute, Sun Yat-sen University, Organ Transplantation Research Center of Guangdong Province, 600# Tianhe Road, Guangzhou, 510630, China. fubinsh@mail.sysu.edu.cn.
Publications dans "Composant-7 du complexe de maintenance des minichromosomes" :
Iron overload disorders represent a variety of conditions that lead to increased total body iron stores and resultant end-organ damage. An elevated ferritin and transferrin-iron saturation can be comm...
Little is known about the prevalence of HFE (homeostatic iron regulator) hemochromatosis in African Americans (AA)....
We defined AA as self-identified AA, blacks, or non-Hispanic blacks. We defined hemochromatosis-associated HFE genotypes as p.C282Y/p.C282Y and p.C282Y/p.H63D. We compiled prevalences of these genotyp...
There were ∼16,287,599 men and ∼17,644,898 women. HFE genotypes and their respective prevalences were: p.C282Y/p.C282Y, 0.00017 (6/34,905) [95% confidence interval 0.000034, 0.00031] and p.C282Y/p.H63...
We conclude that ∼1/25,061 AA >18 y have a hemochromatosis-associated HFE genotype and IO and that ∼1/32,103 AA >18 y have a hemochromatosis-associated HFE genotype and IO-related disease....
Etiological investigation of hyperferritinemia includes a full clinical examination, with the measurement of waist circumference, and simple biological tests including transferrin saturation. The clas...
Liver dysfunction and failure account for a major portion of premature deaths in patients suffering from various iron associated pathogeneses, particularly primary and secondary iron overload disorder...
Ferroptosis is a new type of cell death caused by iron-dependent lipid peroxidation. In recent years, it has been found that ferroptosis can promote the progression of atherosclerosis (AS). Macrophage...
Screening program participants with iron overload (IO) phenotypes without HFE p.C282Y/p.C282Y are incompletely characterized....
We studied white participants who had IO phenotypes without p.C282Y/p.C282Y in post-screening clinical examinations (CE). We defined IO phenotypes as a) elevated serum ferritin (SF) and transferrin sa...
There were 32 men and 26 women (mean age 54±16 y). Median food/supplemental iron intakes were 14.3/0.0 mg/d. Relative risks of HFE genotypes were 12.9 (p.C282Y/p.H63D), 3.0 (p.H63D/p.H63D), 1.9 (p.C28...
In the present 58 screening program participants who had IO phenotypes without HFE p.C282Y/p.C282Y, relative risks of HFE genotypes p.C282Y/p.H63D, p.H63D/p.H63D, and p.C282Y/wt were significantly hig...
Iron overload as a highly risk factor, can be found in almost all human chronic and common diseases. Iron chelators are often used to treat iron overload; however, patient adherence to these chelators...
Transfusion-dependent Diamond-Blackfan anaemia (DBA) patients rapidly develop iron overload and frequently experience cardiac complications. The report by Lecornec and colleagues offers useful details...
Oligodendrocytes are the most iron-rich cells in the brain. Studies have shown that oligodendrocytes are very sensitive to oxidative stress, and iron overload is more likely to cause damage to oligode...