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"description": "Comment diagnostiquer une maladie liée aux IDP ?\nQuels tests sont utilisés pour les IDP ?\nLes IDP peuvent-elles être détectées par imagerie ?\nY a-t-il des biomarqueurs pour les IDP ?\nLes tests génétiques aident-ils pour les IDP ?",
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"description": "Quelles complications peuvent survenir avec les IDP ?\nLes IDP peuvent-elles entraîner des maladies chroniques ?\nY a-t-il des risques de récidive avec les IDP ?\nLes IDP peuvent-elles affecter la qualité de vie ?\nLes IDP sont-elles liées à des troubles mentaux ?",
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"description": "Quels sont les facteurs de risque pour les IDP ?\nL'hérédité joue-t-elle un rôle dans les IDP ?\nL'exposition à des toxines influence-t-elle les IDP ?\nLe mode de vie affecte-t-il le risque d'IDP ?\nLes infections peuvent-elles être un facteur de risque ?",
"url": "https://questionsmedicales.fr/mesh/D064267?mesh_terms=Randomized+Controlled+Trials+as+Topic&page=999#section-facteurs de risque"
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{
"@type": "Question",
"name": "Comment diagnostiquer une maladie liée aux IDP ?",
"position": 1,
"acceptedAnswer": {
"@type": "Answer",
"text": "Le diagnostic repose sur des tests biochimiques et des analyses protéomiques."
}
},
{
"@type": "Question",
"name": "Quels tests sont utilisés pour les IDP ?",
"position": 2,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des techniques comme la spectroscopie RMN et la chromatographie sont courantes."
}
},
{
"@type": "Question",
"name": "Les IDP peuvent-elles être détectées par imagerie ?",
"position": 3,
"acceptedAnswer": {
"@type": "Answer",
"text": "Non, l'imagerie ne détecte pas directement les IDP, mais peut montrer des effets cellulaires."
}
},
{
"@type": "Question",
"name": "Y a-t-il des biomarqueurs pour les IDP ?",
"position": 4,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines IDP peuvent servir de biomarqueurs, mais cela reste en recherche."
}
},
{
"@type": "Question",
"name": "Les tests génétiques aident-ils pour les IDP ?",
"position": 5,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les tests génétiques peuvent identifier des mutations, mais pas spécifiquement les IDP."
}
},
{
"@type": "Question",
"name": "Quels symptômes sont associés aux IDP ?",
"position": 6,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les symptômes varient selon la maladie, incluant fatigue, douleurs et troubles neurologiques."
}
},
{
"@type": "Question",
"name": "Les IDP causent-elles des troubles neurologiques ?",
"position": 7,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, certaines IDP sont liées à des maladies neurodégénératives comme Alzheimer."
}
},
{
"@type": "Question",
"name": "Les IDP sont-elles liées à des cancers ?",
"position": 8,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines IDP sont impliquées dans la régulation tumorale et peuvent favoriser le cancer."
}
},
{
"@type": "Question",
"name": "Peut-on avoir des symptômes sans IDP ?",
"position": 9,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, de nombreux symptômes peuvent être causés par d'autres facteurs non liés aux IDP."
}
},
{
"@type": "Question",
"name": "Les IDP provoquent-elles des douleurs articulaires ?",
"position": 10,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines maladies associées aux IDP peuvent entraîner des douleurs articulaires."
}
},
{
"@type": "Question",
"name": "Peut-on prévenir les maladies liées aux IDP ?",
"position": 11,
"acceptedAnswer": {
"@type": "Answer",
"text": "La prévention est difficile, mais un mode de vie sain peut réduire les risques."
}
},
{
"@type": "Question",
"name": "L'alimentation influence-t-elle les IDP ?",
"position": 12,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une alimentation équilibrée peut soutenir la santé cellulaire, mais ne prévient pas directement les IDP."
}
},
{
"@type": "Question",
"name": "Le stress affecte-t-il les IDP ?",
"position": 13,
"acceptedAnswer": {
"@type": "Answer",
"text": "Le stress peut exacerber les symptômes, mais ne cause pas directement les IDP."
}
},
{
"@type": "Question",
"name": "L'exercice physique aide-t-il avec les IDP ?",
"position": 14,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'exercice régulier peut améliorer la santé générale et réduire certains symptômes."
}
},
{
"@type": "Question",
"name": "Les contrôles médicaux réguliers sont-ils importants ?",
"position": 15,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des contrôles réguliers peuvent aider à détecter précocement des problèmes liés aux IDP."
}
},
{
"@type": "Question",
"name": "Comment traiter les maladies liées aux IDP ?",
"position": 16,
"acceptedAnswer": {
"@type": "Answer",
"text": "Le traitement dépend de la maladie spécifique et peut inclure médicaments et thérapies."
}
},
{
"@type": "Question",
"name": "Y a-t-il des médicaments spécifiques pour les IDP ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "Il n'existe pas de médicaments spécifiques, mais des traitements ciblent les symptômes."
}
},
{
"@type": "Question",
"name": "La thérapie génique aide-t-elle avec les IDP ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "La thérapie génique est en recherche pour certaines maladies liées aux IDP."
}
},
{
"@type": "Question",
"name": "Les traitements naturels sont-ils efficaces pour les IDP ?",
"position": 19,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certains traitements naturels peuvent soulager les symptômes, mais manquent de preuves solides."
}
},
{
"@type": "Question",
"name": "La physiothérapie aide-t-elle avec les IDP ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, la physiothérapie peut aider à gérer les symptômes et améliorer la qualité de vie."
}
},
{
"@type": "Question",
"name": "Quelles complications peuvent survenir avec les IDP ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les complications incluent des troubles neurologiques, des cancers et des maladies auto-immunes."
}
},
{
"@type": "Question",
"name": "Les IDP peuvent-elles entraîner des maladies chroniques ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, certaines IDP sont associées à des maladies chroniques comme la fibromyalgie."
}
},
{
"@type": "Question",
"name": "Y a-t-il des risques de récidive avec les IDP ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines maladies liées aux IDP peuvent avoir des risques de récidive, selon le cas."
}
},
{
"@type": "Question",
"name": "Les IDP peuvent-elles affecter la qualité de vie ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les IDP peuvent gravement affecter la qualité de vie en raison des symptômes chroniques."
}
},
{
"@type": "Question",
"name": "Les IDP sont-elles liées à des troubles mentaux ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines études suggèrent un lien entre IDP et troubles mentaux, mais les recherches continuent."
}
},
{
"@type": "Question",
"name": "Quels sont les facteurs de risque pour les IDP ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les facteurs incluent des prédispositions génétiques, l'âge et des facteurs environnementaux."
}
},
{
"@type": "Question",
"name": "L'hérédité joue-t-elle un rôle dans les IDP ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, certaines IDP ont une composante héréditaire, augmentant le risque de maladies."
}
},
{
"@type": "Question",
"name": "L'exposition à des toxines influence-t-elle les IDP ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'exposition à certaines toxines peut augmenter le risque de maladies liées aux IDP."
}
},
{
"@type": "Question",
"name": "Le mode de vie affecte-t-il le risque d'IDP ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Un mode de vie malsain, comme le tabagisme, peut augmenter le risque de maladies liées aux IDP."
}
},
{
"@type": "Question",
"name": "Les infections peuvent-elles être un facteur de risque ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines infections virales sont associées à un risque accru de maladies liées aux IDP."
}
}
]
}
]
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Hot flashes (HF) are a common adverse event of prolonged tamoxifen use in women with estrogen receptor-positive breast cancer, impacting psychiatric health and quality of life. While desvenlafaxine do...
Pain and anxiety can be considerable obstacles while treating paediatric dental patients. Moderate sedation is needed to treat uncooperative patients....
This study aimed to compare the effectiveness of buccal administration of dexmedetomidine-ketamine combination versus dexmedetomidine....
Fifty-six uncooperative children were randomly assigned into two groups: Group I received buccal dexmedetomidine (2 μg/kg) and ketamine (2 mg/kg) (DEX-KET), whereas Group II received buccal dexmedetom...
There were no significant differences in vital signs or sedation onset between the two groups. DEX-KET group showed shorter recovery time than DEX group (p < .0001). There were no statistically signif...
The combination of dexmedetomidine and ketamine delivered buccally provided a better method of delivering care to uncooperative children with more rapid recovery than dexmedetomidine....
Vedolizumab is indicated for the treatment of chronic pouchitis in the EU. We assessed whether vedolizumab induced mucosal healing (MH) and if MH was associated with clinical improvements....
EARNEST, a randomized, double-blind, placebo-controlled study, evaluated vedolizumab efficacy and safety in adults with chronic pouchitis. Centrally read endoscopic and histological evaluation was per...
Following treatment, mean (SD) number of ulcers in vedolizumab-treated patients reduced from 15.1 (16.4) to 5.0 (4.9) at W14 and 2.7 (3.2) at W34 vs placebo-treated patients with corresponding values ...
Vedolizumab induced endoscopic improvements in patients with chronic pouchitis, which was associated with improved outcomes at W34, particularly in patients achieving MH at W14....
gov number, NCT02790138....
We aimed to summarize survival data from RCTs in patients with GO adenocarcinoma; estimate and explain worst-, typical-, and best-case-scenarios of survival time; and determine if simple multiples of ...
We systematically searched RCTs of systemic therapies for GO adenocarcinoma published 2000-2022. The following key percentiles were extracted from overall survival curves: 90th (worst-case), 75th (low...
We identified 44 trials (22,447 participants). For first line chemotherapy and immunotherapy combined (CI) trials (...
We provide realistic, evidence-based prognostic information as scenarios for survival time which can inform clinical decision-making. Simple multiples of the mOS accurately estimated the percentiles f...
Using an iterative user-centered design process, our team developed a patient-centered adaptive supportive care system, PatientCareAnywhere, that provides comprehensive biopsychosocial screening and s...
This study aims to assess the usability of the new web-based PatientCareAnywhere system and examine the preliminary efficacy of PatientCareAnywhere to improve patient-reported outcomes compared with u...
For phase 1, usability testing participants included patients with cancer (n=4) and caregivers (n=7) who evaluated the software prototype and provided qualitative (eg, interviews) and quantitative (eg...
Participants were highly satisfied with the prototype and reported above-average acceptable usability, with a mean System Usability Scale score of 84.09 (SD 10.02). Qualitative data supported the over...
Overall, PatientCareAnywhere represents a user-friendly, functional, and acceptable supportive care intervention with preliminary efficacy to improve HRQOL among patients diagnosed with cancer. Future...
ClinicalTrials.gov NCT02408406; https://clinicaltrials.gov/study/NCT02408406....
The objective of this meta-analysis was to evaluate the efficacy of administering preoperative oral carbohydrates (CHO) compared to a control treatment in improving postoperative recovery outcomes for...
A meta-analysis of randomized controlled trials....
Through systematic searches in PubMed, Embase, and the Cochrane Library, randomized controlled trials focusing on preoperative oral carbohydrates for patients undergoing LC were collected. Data analys...
The meta-analysis incorporated 19 randomized studies, with a total of 1,568 participants. Meta-analysis results indicated that patients receiving CHO reported notably lower postoperative pain compared...
Preoperative oral carbohydrates may alleviate hunger and pain, and attenuate postoperative insulin resistance more effectively than either overnight fasting or placebo in patients undergoing LC....
In emergency medicine (EM), discerning patient expectations to inform patient-centered care poses unique challenges. We devised a novel questionnaire to facilitate clinicians' understanding of patient...
We conducted a multisite, randomized controlled trial. A brief questionnaire soliciting patient expectations was developed through feedback from clinicians and patients. At the beginning of their visi...
Among the 308 participants, 141 intervention and 123 control exit surveys were collected. In the primary analysis, the intervention group had 2.1 times greater odds of strongly agreeing that their cli...
While more patients reported that their expectations were addressed when the novel tool was used, no significant difference was found for conventional satisfaction measures. Future studies may examine...
Seven days of antibiotics are recommended in the setting of preterm premature rupture of membranes (PPROM) to promote latency. Azithromycin has generally replaced a seven-day course of erythromycin in...
We aim to compare the pharmacokinetics of one-time vs daily dosing of azithromycin in the setting of preterm pre-labor rupture of membranes (PPROM) STUDY DESIGN: This is a randomized clinical trial of...
The study was halted after N=6 enrolled due to lagging enrollment, with 3 in each group. The mean gestational age of enrollment was 27.1±1.7weeks in the 1g group and 31.0±1.4 weeks in the 500mg daily ...
500mg daily dosing of azithromycin maintains higher amniotic fluid concentrations, and more consistently greater than common MICs, over eight days compared to 1g once in the setting of PPROM....
To investigate the short-term effects of 3D-printed and prefabricated foot orthoses on the management of flat feet....
In this single-blinded study, 63 patients with flat feet were enrolled via convenience sampling. They were randomly assigned to the control and experimental groups, receiving prefabricated and customi...
VAS scores at week 0 for the two groups were not statistically significant (p > 0.05). At week 4, the VAS scores of the experimental group reduced significantly (p < 0.001), whereas the VAS scores of ...
Customized 3D-printed orthoses effectively reduced pain and enhanced patient satisfaction with comfort and effectiveness in 4 weeks....