Titre : Inducteurs du cytochrome P-450 CYP2D6

Inducteurs du cytochrome P-450 CYP2D6 : Questions médicales fréquentes

Termes MeSH sélectionnés :

Cochlear Implants
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d'intoxication ?", "url": "https://questionsmedicales.fr/mesh/D065699?mesh_terms=Cochlear+Implants&page=2#section-symptômes" }, { "@type": "MedicalWebPage", "name": "Prévention", "headline": "Prévention sur Inducteurs du cytochrome P-450 CYP2D6", "description": "Comment prévenir l'induction du CYP2D6 ?\nLes patients doivent-ils être informés des inducteurs ?\nQuelles précautions prendre lors de la prescription ?\nLes médecins doivent-ils surveiller les inducteurs ?\nY a-t-il des recommandations pour les prescripteurs ?", "url": "https://questionsmedicales.fr/mesh/D065699?mesh_terms=Cochlear+Implants&page=2#section-prévention" }, { "@type": "MedicalWebPage", "name": "Traitements", "headline": "Traitements sur Inducteurs du cytochrome P-450 CYP2D6", "description": "Comment gérer l'induction du CYP2D6 ?\nPeut-on utiliser des inhibiteurs du CYP2D6 ?\nQuels médicaments sont souvent ajustés ?\nY a-t-il des alternatives aux inducteurs ?\nComment surveiller l'efficacité du traitement ?", 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"acceptedAnswer": { "@type": "Answer", "text": "Oui, l'activité peut être mesurée par des tests de métabolisme de médicaments spécifiques." } }, { "@type": "Question", "name": "Quels médicaments sont des inducteurs connus ?", "position": 5, "acceptedAnswer": { "@type": "Answer", "text": "Des médicaments comme la rifampicine et la carbamazépine sont des inducteurs connus." } }, { "@type": "Question", "name": "Quels symptômes peuvent résulter d'une induction du CYP2D6 ?", "position": 6, "acceptedAnswer": { "@type": "Answer", "text": "Une induction peut entraîner une réduction de l'efficacité des médicaments, causant des symptômes de maladie." } }, { "@type": "Question", "name": "Comment l'induction affecte-t-elle les médicaments ?", "position": 7, "acceptedAnswer": { "@type": "Answer", "text": "Elle peut réduire la concentration plasmatique des médicaments, diminuant leur effet thérapeutique." } }, { "@type": "Question", "name": "Y a-t-il des effets secondaires liés aux inducteurs ?", "position": 8, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des effets secondaires peuvent survenir si les médicaments perdent leur efficacité." } }, { "@type": "Question", "name": "Quels signes cliniques peuvent alerter sur une induction ?", "position": 9, "acceptedAnswer": { "@type": "Answer", "text": "Des signes de non-réponse au traitement peuvent alerter sur une induction du CYP2D6." } }, { "@type": "Question", "name": "L'induction peut-elle causer des symptômes d'intoxication ?", "position": 10, "acceptedAnswer": { "@type": "Answer", "text": "Indirectement, si des médicaments sont sous-dosés, cela peut entraîner des symptômes d'intoxication." } }, { "@type": "Question", "name": "Comment prévenir l'induction du CYP2D6 ?", "position": 11, "acceptedAnswer": { "@type": "Answer", "text": "Éviter les inducteurs connus et surveiller les interactions médicamenteuses." } }, { "@type": "Question", "name": "Les patients doivent-ils être informés des inducteurs ?", "position": 12, "acceptedAnswer": { "@type": "Answer", "text": "Oui, l'éducation des patients sur les inducteurs est cruciale pour éviter des complications." } }, { "@type": "Question", "name": "Quelles précautions prendre lors de la prescription ?", "position": 13, "acceptedAnswer": { "@type": "Answer", "text": "Évaluer les antécédents médicamenteux et les interactions potentielles avant de prescrire." } }, { "@type": "Question", "name": "Les médecins doivent-ils surveiller les inducteurs ?", "position": 14, "acceptedAnswer": { "@type": "Answer", "text": "Oui, une surveillance régulière des médicaments inducteurs est recommandée." } }, { "@type": "Question", "name": "Y a-t-il des recommandations pour les prescripteurs ?", "position": 15, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des lignes directrices existent pour éviter les interactions avec les inducteurs." } }, { "@type": "Question", "name": "Comment gérer l'induction du CYP2D6 ?", "position": 16, "acceptedAnswer": { "@type": "Answer", "text": "Il est essentiel d'ajuster les doses des médicaments affectés par l'induction." } }, { "@type": "Question", "name": "Peut-on utiliser des inhibiteurs du CYP2D6 ?", "position": 17, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des inhibiteurs peuvent être utilisés pour contrer l'effet des inducteurs." } }, { "@type": "Question", "name": "Quels médicaments sont souvent ajustés ?", "position": 18, "acceptedAnswer": { "@type": "Answer", "text": "Les antidépresseurs et les antipsychotiques sont souvent ajustés en cas d'induction." } }, { "@type": "Question", "name": "Y a-t-il des alternatives aux inducteurs ?", "position": 19, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des médicaments non inducteurs peuvent être prescrits pour éviter l'interaction." } }, { "@type": "Question", "name": "Comment surveiller l'efficacité du traitement ?", "position": 20, "acceptedAnswer": { "@type": "Answer", "text": "Des suivis réguliers et des dosages de médicaments sont nécessaires pour évaluer l'efficacité." } }, { "@type": "Question", "name": "Quelles complications peuvent survenir avec l'induction ?", "position": 21, "acceptedAnswer": { "@type": "Answer", "text": "Des complications incluent une inefficacité thérapeutique et des effets indésirables." } }, { "@type": "Question", "name": "L'induction peut-elle entraîner des hospitalisations ?", "position": 22, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des hospitalisations peuvent être nécessaires en cas de complications graves." } }, { "@type": "Question", "name": "Quels risques sont associés à l'induction ?", "position": 23, "acceptedAnswer": { "@type": "Answer", "text": "Les risques incluent des interactions médicamenteuses et des effets secondaires graves." } }, { "@type": "Question", "name": "Comment gérer les complications liées à l'induction ?", "position": 24, "acceptedAnswer": { "@type": "Answer", "text": "Il est crucial d'ajuster les traitements et de surveiller les patients de près." } }, { "@type": "Question", "name": "Y a-t-il des complications à long terme ?", "position": 25, "acceptedAnswer": { "@type": "Answer", "text": "Des complications à long terme peuvent inclure des effets résiduels sur le métabolisme." } }, { "@type": "Question", "name": "Quels sont les facteurs de risque d'induction ?", "position": 26, "acceptedAnswer": { "@type": "Answer", "text": "Les facteurs incluent l'utilisation de certains médicaments et des variations génétiques." } }, { "@type": "Question", "name": "L'âge influence-t-il l'induction du CYP2D6 ?", "position": 27, "acceptedAnswer": { "@type": "Answer", "text": "Oui, l'âge peut affecter le métabolisme et la réponse aux inducteurs." } }, { "@type": "Question", "name": "Les habitudes de vie jouent-elles un rôle ?", "position": 28, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des habitudes comme l'alcool et le tabac peuvent influencer l'induction." } }, { "@type": "Question", "name": "Y a-t-il des prédispositions génétiques ?", "position": 29, "acceptedAnswer": { "@type": "Answer", "text": "Oui, certaines variations génétiques peuvent augmenter le risque d'induction." } }, { "@type": "Question", "name": "Les interactions médicamenteuses sont-elles un facteur ?", "position": 30, "acceptedAnswer": { "@type": "Answer", "text": "Oui, les interactions avec d'autres médicaments peuvent augmenter le risque d'induction." } } ] } ] }

Sources (10000 au total)

Auditory perception in pediatric cochlear implant users with cochlear nerve hypoplasia.

The objectives of this study were to assess auditory perception and speech intelligibility outcomes in children with cochlear nerve (CN) hypoplasia who received cochlear implants (CIs) using Categorie... In total, 40 children who received CI and who were aged between 3 and 18 years were included in this study. The study group included 20 children with CN hypoplasia at least one ear, while the control ... Significant differences were found between the study and control groups' CAP II and SIR scores (p < 0.001). It was found that CAP II scores were positively correlated with SIR scores in the study (r =... Even for children with severe inner ear malformation and CN hypoplasia, CI is an effective treatment modality for auditory perception and speech production. However, it should be noted that CN hypopla...

Interobserver variability of cochlear duct measurements in pediatric cochlear implant candidates.

The objective of the study was to evaluate the proposed cochlear duct length estimation based on the cochlear 'A value'. Furthermore, we assessed the interobserver variability between radiology and ot... Thirteen pediatric cochlear implant candidates were retrospectively analyzed by three otolaryngology physicians (attending physician, second year, and fourth year trainees) and a radiology attending. ... The differences in measurements between the attending otolaryngologist and radiologist were not statistically different, while several significant differences were observed with regard to measurements... Based on these results, cochlear duct length measurement according to the proposed method may be a reliable and cost-effective method. Indeed, otolaryngology training may be sufficient to provide meas...

The value of nonverbal intelligence in cochlear implant.

Congenital sensorineural hearing loss is a common congenital condition.... The purpose of this study was to assess the correlation between nonverbal mental development and the effect of post-cochlear implant in children.... The study is a retrospective analysis of the CI program implemented at the ENT in the Lanzhou University Second Hospital (China). We reviewed data of 225 children who received CI between 2015 and 2018... Preoperative non-verbal DQ correlates with the long-term postoperative result, especially the Eye-hand co-ordination and Performance DQ.... Preoperative non-verbal intelligence would predict postoperative effect. The single postoperative scale does not fully reflect the postoperative result....

Cochlear implants and deep brain stimulators.

With an aging population and increasing utilization of both cochlear implants (CI) to treat hearing loss and deep brain stimulation (DBS) to treat neurodegenerative movement disorders, more patients w... Two illustrative cases of sequential CI followed by DBS are reviewed. Relevant pre-, intra-, and postoperative issues are discussed for both DBS following CI surgery and CI following DBS surgery.... Despite the potential for challenges, sequential CI and DBS (and vice versa) can provide substantial benefit to those individuals with severe hearing loss and movement disorders. A thorough understand...

Effect of Cochlear Implantation on Social Life.

Explore the effects of hearing loss on social life and identify residual social life deficits that remain after cochlear implantation.... Retrospective review of prospectively obtained data.... Tertiary care adult neurotology center.... Adults between the ages of 35 and 83 years were included with either normal hearing (NH) or a cochlear implant (CI).... CI and non-CI-specific quality-of-life (QOL) surveys focused on social and overall QOL.... (1) The difference in QOL survey responses between NH and CI participants. (2) The relationship between CI-specific global and social QOL responses and non-CI-specific social QOL responses in CI users... A total of 51 participants were included: 31 CI users and 20 NH participants. Of the social QOL questionnaires, CI users reported significantly poorer scores on Self-Efficacy in Social Interactions th... CI users self-report similar social life outcomes as their NH peers with the exception of poorer self-efficacy in social situations. Moreover, self-efficacy in social interactions and social isolation...

Assessing Patient Barriers to Cochlear Implantation.

Evaluate barriers that deter adult patients from following through with cochlear implantation.... Retrospective chart review and phone survey.... Single tertiary referral center.... Between January 2019 and August 2021, 113 patients, without a previous cochlear implant (CI), were determined to be candidates for cochlear implantation. Thirty-eight (33.6%) patients deferred cochlea... None.... Demographic, socioeconomic, otologic history, and comorbidity factors associated with deferment of cochlear implantation. Patient survey assessment of factors that had the greatest impact, rated on a ... Out of the 113 patients who met inclusion criteria, 75 (66.3%) underwent cochlear implantation and 38 (33.6%) patients deferred. Comparing implanted versus deferred groups, there was no statistical di... The greatest concern among the patients was the fear of losing residual hearing. Spending greater time educating patients about the success and failure rates of cochlear implantation may reduce patien...

Investigating Socioeconomic Barriers to Cochlear Implantation.

To explore socioeconomic disparities in cochlear implant evaluation (CIE) referrals and cochlear implantation.... Retrospective chart review.... Tertiary referral academic center.... Adult patients (n = 271) with an audiogram performed between 2015 and 2019 with a pure-tone average of at least 60 dB and word recognition score of 60% or less in the better-hearing ear or no word rec... There were 122 insured patients referred to CIE where 84 were considered cochlear implant (CI) candidates and 73 were implanted. In multivariate regression analysis, non-English-speaking patients were... Primary language spoken was associated with a disparity in rates of CIE referral. Insurance type did influence rate of cochlear implantation once patients completed CIE and were considered CI candidat...

Cochlear implantation in systemic autoimmune disease.

Autoimmune inner ear disease (AIED) is a rare, but likely underrecognized cause of hearing loss. However, hearing loss is common in systemic autoimmune disease and it is important for the clinician to... Hearing loss in AIED tends to be progressive and bilateral, but up to 40% can present as sudden hearing loss and one-third can present unilaterally. HSP-70 serology may help with diagnosis and may pre... Diagnosis of AIED is largely clinical, and a strong index of suspicion is required. Multidisciplinary care is crucial for optimal management. Cochlear implant outcomes are generally excellent, but the...