Cortical plasticity with bimodal hearing in children with asymmetric hearing loss.


Journal

Hearing research
ISSN: 1878-5891
Titre abrégé: Hear Res
Pays: Netherlands
ID NLM: 7900445

Informations de publication

Date de publication:
02 2019
Historique:
received: 16 11 2017
revised: 12 01 2018
accepted: 09 02 2018
pubmed: 6 3 2018
medline: 30 5 2020
entrez: 6 3 2018
Statut: ppublish

Résumé

This longitudinal study aimed to identify auditory plasticity promoted by a cochlear implant in children with asymmetric hearing loss. Participants included 10 children who experienced (mean ± SD) 3.1 ± 3.6 years of asymmetric hearing (difference of 47.2 ± 47.6 dB) before receiving an implant at age 8.7 ± 5.1 years. Multi-channel electroencephalography was measured at initial implant use (5.8 ± 3.2 days) and after 10.2 ± 4.1 months in each child. Monaurally presented stimuli consisted of 36 ms trains of 9 acoustic clicks/biphasic electric pulses at a rate of 250 Hz, repeated at 1 Hz. The time-restricted artifact and coherent source suppression (TRACS) beamformer was used to locate sources underlying peak amplitudes of cortical responses. Results indicated consistent activity from the non-implanted ear but significant implant-driven changes to the auditory cortices. Initially, the newly implanted ear evoked activity which strongly lateralized to the ipsilateral auditory cortex and contributed to a significant aural preference for implant stimulation in children with limited acoustic experience pre-implantation. Cochlear implant use reversed these abnormalities, but the resolution was limited in children with longer periods of asymmetric hearing. These findings suggest that early implantation of children with asymmetric hearing rapidly restores hemispheric representations of bilateral auditory input in the auditory cortex. Most recorded changes were isolated to pathways stimulated by the cochlear implant, potentially reflecting an abnormal independence of the bilateral pathways with possible consequences for binaural integration in these bimodal listeners.

Identifiants

pubmed: 29502907
pii: S0378-5955(17)30557-9
doi: 10.1016/j.heares.2018.02.003
pii:
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

88-98

Informations de copyright

Copyright © 2018 Elsevier B.V. All rights reserved.

Auteurs

Melissa J Polonenko (MJ)

Neurosciences & Mental Health, The Hospital for Sick Children, Toronto, ON, Canada; Institute of Medical Sciences, The University of Toronto, Toronto, ON, Canada; Collaborative Program in Neuroscience, The University of Toronto, Toronto, ON, Canada. Electronic address: melissa.polonenko@mail.utoronto.ca.

Blake C Papsin (BC)

Institute of Medical Sciences, The University of Toronto, Toronto, ON, Canada; Department of Otolaryngology - Head & Neck Surgery, The Hospital for Sick Children, Toronto, ON, Canada; Department of Otolaryngology - Head & Neck Surgery, The University of Toronto, Toronto, ON, Canada.

Karen A Gordon (KA)

Neurosciences & Mental Health, The Hospital for Sick Children, Toronto, ON, Canada; Institute of Medical Sciences, The University of Toronto, Toronto, ON, Canada; Collaborative Program in Neuroscience, The University of Toronto, Toronto, ON, Canada; Department of Otolaryngology - Head & Neck Surgery, The Hospital for Sick Children, Toronto, ON, Canada; Department of Otolaryngology - Head & Neck Surgery, The University of Toronto, Toronto, ON, Canada.

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Classifications MeSH