Cortical plasticity with bimodal hearing in children with asymmetric hearing loss.
Adolescent
Age Factors
Auditory Cortex
/ physiopathology
Auditory Threshold
Brain Mapping
Child
Child, Preschool
Cochlear Implants
Electroencephalography
Evoked Potentials, Auditory
Female
Functional Laterality
Hearing Loss, Bilateral
/ physiopathology
Hearing Loss, Unilateral
/ physiopathology
Humans
Infant
Longitudinal Studies
Male
Neuronal Plasticity
/ physiology
Time Factors
Asymmetric hearing loss
Auditory cortex
Auditory evoked potentials
Bimodal hearing
Cochlear implant
Development
EEG
Unilateral deafness
Journal
Hearing research
ISSN: 1878-5891
Titre abrégé: Hear Res
Pays: Netherlands
ID NLM: 7900445
Informations de publication
Date de publication:
02 2019
02 2019
Historique:
received:
16
11
2017
revised:
12
01
2018
accepted:
09
02
2018
pubmed:
6
3
2018
medline:
30
5
2020
entrez:
6
3
2018
Statut:
ppublish
Résumé
This longitudinal study aimed to identify auditory plasticity promoted by a cochlear implant in children with asymmetric hearing loss. Participants included 10 children who experienced (mean ± SD) 3.1 ± 3.6 years of asymmetric hearing (difference of 47.2 ± 47.6 dB) before receiving an implant at age 8.7 ± 5.1 years. Multi-channel electroencephalography was measured at initial implant use (5.8 ± 3.2 days) and after 10.2 ± 4.1 months in each child. Monaurally presented stimuli consisted of 36 ms trains of 9 acoustic clicks/biphasic electric pulses at a rate of 250 Hz, repeated at 1 Hz. The time-restricted artifact and coherent source suppression (TRACS) beamformer was used to locate sources underlying peak amplitudes of cortical responses. Results indicated consistent activity from the non-implanted ear but significant implant-driven changes to the auditory cortices. Initially, the newly implanted ear evoked activity which strongly lateralized to the ipsilateral auditory cortex and contributed to a significant aural preference for implant stimulation in children with limited acoustic experience pre-implantation. Cochlear implant use reversed these abnormalities, but the resolution was limited in children with longer periods of asymmetric hearing. These findings suggest that early implantation of children with asymmetric hearing rapidly restores hemispheric representations of bilateral auditory input in the auditory cortex. Most recorded changes were isolated to pathways stimulated by the cochlear implant, potentially reflecting an abnormal independence of the bilateral pathways with possible consequences for binaural integration in these bimodal listeners.
Identifiants
pubmed: 29502907
pii: S0378-5955(17)30557-9
doi: 10.1016/j.heares.2018.02.003
pii:
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
88-98Informations de copyright
Copyright © 2018 Elsevier B.V. All rights reserved.