Swallow-breathing coordination during incremental ascent to altitude.
Airflow
Airway protection
Apnea duration
Electromyograms
High altitude ascent
Swallow coordination
Journal
Respiratory physiology & neurobiology
ISSN: 1878-1519
Titre abrégé: Respir Physiol Neurobiol
Pays: Netherlands
ID NLM: 101140022
Informations de publication
Date de publication:
07 2019
07 2019
Historique:
received:
14
04
2018
revised:
11
06
2018
accepted:
12
06
2018
pubmed:
20
6
2018
medline:
3
4
2020
entrez:
20
6
2018
Statut:
ppublish
Résumé
Swallow and breathing are highly coordinated behaviors reliant on shared anatomical space and neural pathways. Incremental ascent to high altitudes results in hypoxia/hypocapnic conditions altering respiratory drive, however it is not known whether these changes also alter swallow. We examined the effect of incremental ascent (1045 m, 3440 m and 4371 m) on swallow motor pattern and swallow-breathing coordination in seven healthy adults. Submental surface electromyograms (sEMG) and spirometry were used to evaluate swallow triggered by saliva and water infusion. Swallow-breathing phase preference was different between swallows initiated by saliva versus water. With ascent, saliva swallows changed to a dominate pattern of occurrence during the transition from inspiration to expiration. Additionally, water swallows demonstrated a significant decrease in submental sEMG duration and a shift in submental activity to earlier in the apnea period, especially at 4371 m. Our results suggest that there are changes in swallow-breathing coordination and swallow production that likely increase airway protection with incremental ascent to high altitude. The adaptive changes in swallow were likely due to the exposure to hypoxia and hypocapnia, along with airway irritation.
Identifiants
pubmed: 29920337
pii: S1569-9048(18)30125-3
doi: 10.1016/j.resp.2018.06.005
pmc: PMC6298863
mid: NIHMS979850
pii:
doi:
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
121-126Subventions
Organisme : NHLBI NIH HHS
ID : R00 HL111215
Pays : United States
Organisme : NINDS NIH HHS
ID : R01 NS110169
Pays : United States
Informations de copyright
Copyright © 2018 Elsevier B.V. All rights reserved.
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