Metal sensitive and DNA concentration dependent structural rearrangement of short oligonucleotide into large suprastructures.

Base Sequence Cations / chemistry Circular Dichroism / methods DNA / chemistry G-Quadruplexes Metals / chemistry Microscopy, Atomic Force / methods Nucleic Acid Conformation Nucleic Acid Denaturation Oligonucleotides / chemistry
DNA nanodevice G-quadruplex G-wire UV-thermal denaturation atomic force microscopy native gel electrophoresis

Journal

Journal of biomolecular structure & dynamics
ISSN: 1538-0254
Titre abrégé: J Biomol Struct Dyn
Pays: England
ID NLM: 8404176

Informations de publication

Date de publication:
Jun 2019
Historique:
pubmed: 27 7 2018
medline: 23 6 2020
entrez: 27 7 2018
Statut: ppublish

Résumé

Formation of higher order structures, such as G-quadruplexes and G-quadruplex based large suprastructures into long G-wires and liquid crystals is promising elements for use in healthcare for drug delivery as they are mechanically and thermally stable. In this study, we studied the structures of short 11-mer oligonucleotide 5'-G

Identifiants

DOI: 10.1080/07391102.2018.1484816 PMID: 30047312
pubmed: 30047312
doi: 10.1080/07391102.2018.1484816
doi:

Substances chimiques

Cations 0
Metals 0
Oligonucleotides 0
DNA 9007-49-2

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

2211-2218

Auteurs

J Shankaraswamy (J)

a Amity International Centre for Post Harvest Technology and Cold Chain Management, Amity University , Noida , Uttar Pradesh 201313 , India.

Shikhar Tyagi (S)

b Department of Biotechnology, Amity University Uttar Pradesh, Noida 201313, India.

Anju Singh (A)

c Department of Chemistry, Nucleic Acids Research laboratory , University of Delhi (North Campus) , Delhi 110007 , India.

Daisuke Miyoshi (D)

d Faculty of Frontiers of Innovative Research in Science and Technology (FIRST) , Konan University , 7-1-20 Minatojima-minamimachi , Chuo-ku, Kobe , Hyogo 650-0047 , Japan.

Sarika Saxena (S)

b Department of Biotechnology, Amity University Uttar Pradesh, Noida 201313, India.

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Classifications MeSH

questionsmedicales.fr › Sciences de l'information › Sources d'information › Services d'information › Documentation › Données de séquences moléculaires › Séquence nucléotidique › Metal sensitive and DNA concentration...
questionsmedicales.fr › Produits chimiques inorganiques › Électrolytes › Ions › Cations › Metal sensitive and DNA concentration...
questionsmedicales.fr › Techniques d'investigation › Techniques de chimie analytique › Analyse spectrale › Dichroïsme circulaire › Metal sensitive and DNA concentration...
questionsmedicales.fr › Acides nucléiques, nucléotides et nucléosides › Acides nucléiques › ADN › Metal sensitive and DNA concentration...
questionsmedicales.fr › Phénomènes génétiques › Structures génétiques › Conformation d'acide nucléique › G-quadruplexes › Metal sensitive and DNA concentration...
questionsmedicales.fr › Produits chimiques inorganiques › Métaux › Metal sensitive and DNA concentration...
questionsmedicales.fr › Techniques d'investigation › Microscopie à sonde à balayage › Microscopie à force atomique › Metal sensitive and DNA concentration...
questionsmedicales.fr › Phénomènes génétiques › Structures génétiques › Conformation d'acide nucléique › Metal sensitive and DNA concentration...
questionsmedicales.fr › Phénomènes génétiques › Dénaturation d'acide nucléique › Metal sensitive and DNA concentration...
questionsmedicales.fr › Acides nucléiques, nucléotides et nucléosides › Nucléotides › Polynucléotides › Oligonucléotides › Metal sensitive and DNA concentration...