NO

Adolescent Adult Asthma / metabolism Biomarkers / metabolism Breath Tests Cross-Sectional Studies Female Humans Longitudinal Studies Male Middle Aged Nitric Oxide / metabolism Rhinitis, Allergic / metabolism Tasmania
asthma atopy exhaled breath condensate rhinitis total nitric oxide

Journal

Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology
ISSN: 1365-2222
Titre abrégé: Clin Exp Allergy
Pays: England
ID NLM: 8906443

Informations de publication

Date de publication:
02 2019
Historique:
received: 20 12 2017
revised: 27 07 2018
accepted: 29 07 2018
pubmed: 15 8 2018
medline: 2 4 2020
entrez: 15 8 2018
Statut: ppublish

Résumé

Asthma and allergic diseases are heterogeneous. Measurement of biomarkers in exhaled breath condensate (EBC) may help to discriminate between different phenotypes and may assist with clinical prognostication. We aimed to assess associations between total nitric oxide products (NO Cross-sectional analyses were nested within two Australian longitudinal studies, the Melbourne Atopy Cohort Study (MACS, mean age 17.8 years) and the Tasmanian Longitudinal Health Study (TAHS, mean age 49.4 years). Levels of EBC NO Atopy, with or without asthma or rhinitis, was associated with increased EBC NO In these population-based samples, EBC NO

Sections du résumé

BACKGROUND
Asthma and allergic diseases are heterogeneous. Measurement of biomarkers in exhaled breath condensate (EBC) may help to discriminate between different phenotypes and may assist with clinical prognostication.
OBJECTIVES
We aimed to assess associations between total nitric oxide products (NO
METHODS
Cross-sectional analyses were nested within two Australian longitudinal studies, the Melbourne Atopy Cohort Study (MACS, mean age 17.8 years) and the Tasmanian Longitudinal Health Study (TAHS, mean age 49.4 years). Levels of EBC NO
RESULTS
Atopy, with or without asthma or rhinitis, was associated with increased EBC NO
CONCLUSIONS AND CLINICAL RELEVANCE
In these population-based samples, EBC NO

Identifiants

DOI: 10.1111/cea.13251 PMID: 30107057
pubmed: 30107057
doi: 10.1111/cea.13251
doi:

Substances chimiques

Biomarkers 0
Nitric Oxide 31C4KY9ESH

Types de publication

Clinical Trial Journal Article Multicenter Study Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

171-179

Informations de copyright

© 2018 John Wiley & Sons Ltd.

Auteurs

Fahad M Aldakheel (FM)

Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, King Saud University, Riyadh, Saudi Arabia.
ORCID: 0000-0001-8047-8650

Jane E Bourke (JE)

Department of Pharmacology, Biomedicine Discovery Institute, Monash University, Melbourne, Vic., Australia.

Paul S Thomas (PS)

Department of Respiratory Medicine & Prince of Wales Hospital Clinical School, University of New South Wales, Kensington, NSW, Australia.

Melanie C Matheson (MC)

Allergy and Lung Health Unit, Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Vic., Australia.
Murdoch Children's Research Institute, Melbourne, Vic., Australia.

Michael J Abramson (MJ)

School of Public Health & Preventive Medicine, Monash University, Melbourne, Vic., Australia.

Garun S Hamilton (GS)

School of Clinical Sciences, Monash University, Melbourne, Vic., Australia.
Monash Lung and Sleep, Monash Health, Melbourne, Vic., Australia.

Caroline J Lodge (CJ)

Allergy and Lung Health Unit, Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Vic., Australia.
Murdoch Children's Research Institute, Melbourne, Vic., Australia.
ORCID: 0000-0002-2342-3888

Bruce R Thompson (BR)

Allergy, Immunology and Respiratory Medicine, the Alfred Hospital, Melbourne, Vic., Australia.
Central Clinical School, Monash University, Melbourne, Vic., Australia.

E Haydn Walters (EH)

School of Medicine, University of Tasmania, Hobart, TAS, Australia.

Katrina J Allen (KJ)

Murdoch Children's Research Institute, Melbourne, Vic., Australia.
ORCID: 0000-0002-1921-4493

Bircan Erbas (B)

School of Public Health, La Trobe University, Melbourne, Vic., Australia.

Jennifer L Perret (JL)

Allergy and Lung Health Unit, Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Vic., Australia.
Centre for Air quality and health Research and evaluation (CAR), Melbourne, Vic., Australia.

Shyamali C Dharmage (SC)

Allergy and Lung Health Unit, Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Vic., Australia.
Murdoch Children's Research Institute, Melbourne, Vic., Australia.

Adrian J Lowe (AJ)

Allergy and Lung Health Unit, Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Vic., Australia.
Murdoch Children's Research Institute, Melbourne, Vic., Australia.

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Classifications MeSH

questionsmedicales.fr › Personnes › Tranches d'âge › Adolescent › NO
questionsmedicales.fr › Personnes › Tranches d'âge › Adulte › NO
questionsmedicales.fr › Maladies du système immunitaire › Hypersensibilité › Hypersensibilité immédiate › Hypersensibilité respiratoire › Asthme › NO
questionsmedicales.fr › Facteurs biologiques › Marqueurs biologiques › NO
questionsmedicales.fr › Diagnostic › Techniques et procédures diagnostiques › Tests d'analyse de l'haleine › NO
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Caractéristiques des études épidémiologiques › Études épidémiologiques › Études transversales › NO
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › NO
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Caractéristiques des études épidémiologiques › Études épidémiologiques › Études de cohortes › Études longitudinales › NO
questionsmedicales.fr › Personnes › Tranches d'âge › Adulte › Adulte d'âge moyen › NO
questionsmedicales.fr › Produits chimiques inorganiques › Composés de l'oxygène › Oxydes › Oxydes d'azote › Monoxyde d'azote › NO
questionsmedicales.fr › Maladies du système immunitaire › Hypersensibilité › Hypersensibilité immédiate › Hypersensibilité respiratoire › Rhinite allergique › NO
questionsmedicales.fr › Régions géographiques › Océanie › Australasie › Australie › Tasmanie › NO