Lung Retransplantation Due to Chronic Lung Allograph Dysfunction: Results From a Spanish Transplant Unit.
Resultados del retrasplante pulmonar por disfunción crónica del injerto pulmonar en un centro trasplantador: Hospital Vall D’Hebron de Barcelona.
Chronic lung allograft dysfunction
Disfunción crónica del injerto
Lung retransplantation
Lung transplantation
Retrasplante pulmonar
Trasplante pulmonar
Journal
Archivos de bronconeumologia
ISSN: 2173-5751
Titre abrégé: Arch Bronconeumol (Engl Ed)
Pays: Spain
ID NLM: 101777538
Informations de publication
Date de publication:
Mar 2019
Mar 2019
Historique:
received:
21
05
2018
revised:
04
07
2018
accepted:
25
07
2018
pubmed:
23
8
2018
medline:
29
5
2020
entrez:
23
8
2018
Statut:
ppublish
Résumé
Long-term survival of lung transplantation (LT) patients is mainly limited by the development of chronic lung allograft dysfunction (CLAD). Lung retransplantation (LR) is an alternative for a selected population. The aim of this study was to review the LR experience in our center. We conducted a retrospective study of patients undergoing LR between August 1990 and July 2017. Fourteen LR out of a total of 998 (1.4%) LT were performed. Twelve patients (85.7%) underwent LR due to CLAD: 10 (71.4%) because of bronchiolitis obliterans syndrome and 2 (14.3%) due to restrictive allograft syndrome. LR was performed in 2 patients within 30 days of the first LT. In those who underwent LR due to CLAD, mean time between the first LT and LR was 48 months, and mean duration of invasive mechanical ventilation was 32 days. The increase in FEV LR is a therapeutic option in selected patients with CLAD, with acceptable survival. Indication for LR early after LT shows poor outcomes.
Identifiants
pubmed: 30131203
pii: S0300-2896(18)30318-1
doi: 10.1016/j.arbres.2018.07.025
pii:
doi:
Types de publication
Journal Article
Langues
eng
spa
Sous-ensembles de citation
IM
Pagination
134-138Informations de copyright
Copyright © 2018 SEPAR. Publicado por Elsevier España, S.L.U. All rights reserved.