A transdiagnostic dimensional approach towards a neuropsychological assessment for addiction: an international Delphi consensus study.


Journal

Addiction (Abingdon, England)
ISSN: 1360-0443
Titre abrégé: Addiction
Pays: England
ID NLM: 9304118

Informations de publication

Date de publication:
06 2019
Historique:
received: 22 07 2018
revised: 02 08 2018
accepted: 14 08 2018
pubmed: 23 8 2018
medline: 17 7 2020
entrez: 23 8 2018
Statut: ppublish

Résumé

The US National Institutes of Mental Health Research Domain Criteria (RDoC) seek to stimulate research into biologically validated neuropsychological dimensions across mental illness symptoms and diagnoses. The RDoC framework comprises 39 functional constructs designed to be revised and refined, with the overall goal of improving diagnostic validity and treatments. This study aimed to reach a consensus among experts in the addiction field on the 'primary' RDoC constructs most relevant to substance and behavioural addictions. Forty-four addiction experts were recruited from Australia, Asia, Europe and the Americas. The Delphi technique was used to determine a consensus as to the degree of importance of each construct in understanding the essential dimensions underpinning addictive behaviours. Expert opinions were canvassed online over three rounds (97% completion rate), with each consecutive round offering feedback for experts to review their opinions. Seven constructs were endorsed by ≥ 80% of experts as 'primary' to the understanding of addictive behaviour: five from the Positive Valence System (reward valuation, expectancy, action selection, reward learning, habit); one from the Cognitive Control System (response selection/inhibition); and one expert-initiated construct (compulsivity). These constructs were rated to be related differentially to stages of the addiction cycle, with some linked more closely to addiction onset and others more to chronicity. Experts agreed that these neuropsychological dimensions apply across a range of addictions. The study offers a novel and neuropsychologically informed theoretical framework, as well as a cogent step forward to test transdiagnostic concepts in addiction research, with direct implications for assessment, diagnosis, staging of disorder, and treatment.

Sections du résumé

BACKGROUND
The US National Institutes of Mental Health Research Domain Criteria (RDoC) seek to stimulate research into biologically validated neuropsychological dimensions across mental illness symptoms and diagnoses. The RDoC framework comprises 39 functional constructs designed to be revised and refined, with the overall goal of improving diagnostic validity and treatments. This study aimed to reach a consensus among experts in the addiction field on the 'primary' RDoC constructs most relevant to substance and behavioural addictions.
METHODS
Forty-four addiction experts were recruited from Australia, Asia, Europe and the Americas. The Delphi technique was used to determine a consensus as to the degree of importance of each construct in understanding the essential dimensions underpinning addictive behaviours. Expert opinions were canvassed online over three rounds (97% completion rate), with each consecutive round offering feedback for experts to review their opinions.
RESULTS
Seven constructs were endorsed by ≥ 80% of experts as 'primary' to the understanding of addictive behaviour: five from the Positive Valence System (reward valuation, expectancy, action selection, reward learning, habit); one from the Cognitive Control System (response selection/inhibition); and one expert-initiated construct (compulsivity). These constructs were rated to be related differentially to stages of the addiction cycle, with some linked more closely to addiction onset and others more to chronicity. Experts agreed that these neuropsychological dimensions apply across a range of addictions.
CONCLUSIONS
The study offers a novel and neuropsychologically informed theoretical framework, as well as a cogent step forward to test transdiagnostic concepts in addiction research, with direct implications for assessment, diagnosis, staging of disorder, and treatment.

Identifiants

pubmed: 30133930
doi: 10.1111/add.14424
pmc: PMC6386631
mid: NIHMS1002854
doi:

Types de publication

Consensus Development Conference Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1095-1109

Subventions

Organisme : NIDA NIH HHS
ID : R01 DA041528
Pays : United States
Organisme : NCCIH NIH HHS
ID : R01 AT010627
Pays : United States
Organisme : NCATS NIH HHS
ID : UL1 TR001863
Pays : United States
Organisme : Medical Research Council
ID : MC_UU_00011/7
Pays : United Kingdom
Organisme : Medical Research Council
ID : MR/K023195/1
Pays : United Kingdom
Organisme : Medical Research Council
ID : MR/N02530X/1
Pays : United Kingdom
Organisme : Medical Research Council
ID : MR/P008747/1
Pays : United Kingdom
Organisme : NIDA NIH HHS
ID : K01 DA037452
Pays : United States

Commentaires et corrections

Type : CommentIn
Type : CommentIn

Informations de copyright

© 2018 The Authors. Addiction published by John Wiley & Sons Ltd on behalf of Society for the Study of Addiction.

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Auteurs

Murat Yücel (M)

Brain and Mental Health Research Hub, Monash Institute of Cognitive and Clinical Neurosciences (MICCN) and School of Psychological Sciences, Monash University, Melbourne, Australia.

Erin Oldenhof (E)

Brain and Mental Health Research Hub, Monash Institute of Cognitive and Clinical Neurosciences (MICCN) and School of Psychological Sciences, Monash University, Melbourne, Australia.

Serge H Ahmed (SH)

Institut des Maladies Neurodégénératives, Université de Bordeaux, Bordeaux, France.

David Belin (D)

Department of Psychology, University of Cambridge, Cambridge, UK.

Joel Billieux (J)

Addictive and Compulsive Behaviours Laboratory (ACB-lab), Institute for Health and Behaviours, University of Luxembourg, Esch-sur-Alzette, Luxembourg.

Henrietta Bowden-Jones (H)

Department of Medicine, Imperial College, London, UK.

Adrian Carter (A)

Brain and Mental Health Research Hub, Monash Institute of Cognitive and Clinical Neurosciences (MICCN) and School of Psychological Sciences, Monash University, Melbourne, Australia.

Samuel R Chamberlain (SR)

Department of Psychiatry, University of Cambridge; and Cambridge and Peterborough NHS Foundation Trust (CPFT), Cambridge, UK.

Luke Clark (L)

Centre for Gambling Research at UBC, Department of Psychology, University of British Columbia, Vancouver, BC, Canada.

Jason Connor (J)

Discipline of Psychiatry, Faculty of Medicine, and Centre for Youth Substance Abuse Research, The University of Queensland, Brisbane, Australia.

Mark Daglish (M)

Alcohol and Drug Service, Royal Brisbane and Women's Hospital, Metro North HHS, Queensland Health and Discipline of Psychiatry, The University of Queensland, Australia.

Geert Dom (G)

Antwerp University (UA), Collaborative Antwerp Psychiatric Research Institute (CAPRI), Antwerp, Belgium.

Pinhas Dannon (P)

Department of Psychiatry, the Sackler School of Medicine and Tel Aviv University, Tel Aviv, Israel.

Theodora Duka (T)

Sussex Addiction Research and Intervention Centre, School of Psychology, University of Sussex, Brighton, UK.

Maria Jose Fernandez-Serrano (MJ)

Departamento de Psicología, Universidad de Jaén, Spain.

Matt Field (M)

Department of Psychology, University of Sheffield, Sheffield, UK.

Ingmar Franken (I)

Institute of Psychology, Erasmus School of Social Sciences and Behavioral Sciences, Erasmus University, Rotterdam, the Netherlands.

Rita Z Goldstein (RZ)

Department of Psychiatry and Neuroscience, Icahn School of Medicine at Mount Sinai, NY, USA.

Raul Gonzalez (R)

Center for Children and Families, Department of Psychology, Florida International University, Miami, FL.

Anna E Goudriaan (AE)

Arkin Mental Health and Amsterdam UMC, University of Amsterdam, Department of Psychiatry, Amsterdam Institute for Addiction Research, Amsterdam, Netherlands.

Jon E Grant (JE)

Department of Psychiatry and Behavioral Neuroscience, University of Chicago, Chicago, IL, USA.

Matthew J Gullo (MJ)

Centre for Youth Substance Abuse Research, The University of Queensland, Brisbane, Australia.

Robert Hester (R)

School of Psychological Sciences, University of Melbourne, Melbourne, Australia.

David C Hodgins (DC)

Department of Psychology, University of Calgary, Calgary, Canada.

Bernard Le Foll (B)

Translational Addiction Research Laboratory, Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health (CAMH), Toronto, Canada.
Department of Family and Community Medicine, Pharmacology and Toxicology, Psychiatry, University of Toronto, Toronto, Canada.

Rico S C Lee (RSC)

Brain and Mental Health Research Hub, Monash Institute of Cognitive and Clinical Neurosciences (MICCN) and School of Psychological Sciences, Monash University, Melbourne, Australia.

Anne Lingford-Hughes (A)

Neuropsychopharmacology Unit, Centre for Psychiatry, Division of Brain Sciences, Imperial College, London, UK.

Valentina Lorenzetti (V)

School of Psychology, Faculty of Health Sciences, Australian Catholic University, Melbourne, Australia.

Scott J Moeller (SJ)

Department of Psychiatry, Stony Brook University School of Medicine, Stony Brook, NY, USA.

Marcus R Munafò (MR)

MRC Integrative Epidemiology Unit at the University of Bristol and UK Centre for Tobacco and Alcohol Studies, School of Experimental Psychology, University of Bristol, Bristol, UK.

Brian Odlaug (B)

Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
H. Lundbeck A/S, Valby, Denmark.

Marc N Potenza (MN)

Departments of Psychiatry and Neuroscience, Child Study Center, Yale University School of Medicine and Connecticut Mental Health Center and Connecticut Council on Problem Gambling, New Haven, CT, USA.

Rebecca Segrave (R)

Brain and Mental Health Research Hub, Monash Institute of Cognitive and Clinical Neurosciences (MICCN) and School of Psychological Sciences, Monash University, Melbourne, Australia.

Zsuzsika Sjoerds (Z)

Department of Neurology, Max-Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany.
Cognitive Psychology Unit, Institute of Psychology, and Leiden Institute for Brain and Cognition, Leiden University, Leiden, the Netherlands.

Nadia Solowij (N)

School of Psychology and Illawarra Health and Medical Research Institute, University of Wollongong, Wollongong, NSW, Australia.
The Australian Centre for Cannabinoid Clinical and Research Excellence (ACRE), New Lambton Heights NSW, Australia.

Wim van den Brink (W)

Amsterdam UMC, University of Amsterdam, Department of Psychiatry, Amsterdam Institute for Addiction Research, Amsterdam, Netherlands.

Ruth J van Holst (RJ)

Amsterdam UMC, University of Amsterdam, Department of Psychiatry, Amsterdam Institute for Addiction Research, Amsterdam, Netherlands.

Valerie Voon (V)

Department of Psychiatry, University of Cambridge, Cambridge, UK.

Reinout Wiers (R)

Addiction, Development and Psychopathology (ADAPT)-lab, Deptartment of Psychology, University of Amsterdam, the Netherlands.

Leonardo F Fontenelle (LF)

Brain and Mental Health Research Hub, Monash Institute of Cognitive and Clinical Neurosciences (MICCN) and School of Psychological Sciences, Monash University, Melbourne, Australia.

Antonio Verdejo-Garcia (A)

Brain and Mental Health Research Hub, Monash Institute of Cognitive and Clinical Neurosciences (MICCN) and School of Psychological Sciences, Monash University, Melbourne, Australia.

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