Refractory Palmoplantar Pustular Psoriasis Treated With High-Dose Ustekinumab After Initial Failure.
inflammatory bowel disease
palmoplantar pustular psoriasis
ustekinumab
Journal
Journal of cutaneous medicine and surgery
ISSN: 1615-7109
Titre abrégé: J Cutan Med Surg
Pays: United States
ID NLM: 9614685
Informations de publication
Date de publication:
Historique:
pubmed:
25
8
2018
medline:
25
6
2019
entrez:
25
8
2018
Statut:
ppublish
Résumé
Palmoplantar pustular psoriasis (PPPP) is a form of psoriasis that can be difficult to treat. We describe a case of PPPP in a patient who failed multiple therapies, including ustekinumab. The patient subsequently developed inflammatory bowel disease (IBD), and restarting ustekinumab, with inflammatory bowel disease loading doses and optimization, resulted in complete resolution of her PPPP. This success occurred after she developed tachyphylaxis against the usual dosing of ustekinumab, demonstrating a recapture of the treatment response.
Identifiants
pubmed: 30141337
doi: 10.1177/1203475418795823
doi:
Substances chimiques
Dermatologic Agents
0
Ustekinumab
FU77B4U5Z0
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM