Inhibitory and excitatory mechanisms in the human cingulate-cortex support reinforcement learning: A functional Proton Magnetic Resonance Spectroscopy study.
Anterior cingulate cortex
E/I-balance
GABA
Reinforcement learning
fMRS
Journal
NeuroImage
ISSN: 1095-9572
Titre abrégé: Neuroimage
Pays: United States
ID NLM: 9215515
Informations de publication
Date de publication:
01 01 2019
01 01 2019
Historique:
received:
12
05
2018
revised:
10
08
2018
accepted:
07
09
2018
pubmed:
12
9
2018
medline:
5
2
2019
entrez:
12
9
2018
Statut:
ppublish
Résumé
The dorsal anterior cingulate cortex (dACC) is crucial for motivation, reward- and error-guided decision-making, yet its excitatory and inhibitory mechanisms remain poorly explored in humans. In particular, the balance between excitation and inhibition (E/I), demonstrated to play a role in animal studies, is difficult to measure in behaving humans. Here, we used functional magnetic-resonance-spectroscopy (
Identifiants
pubmed: 30201464
pii: S1053-8119(18)30801-2
doi: 10.1016/j.neuroimage.2018.09.016
pii:
doi:
Substances chimiques
Glutamic Acid
3KX376GY7L
gamma-Aminobutyric Acid
56-12-2
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
25-35Informations de copyright
Copyright © 2018 Elsevier Inc. All rights reserved.