Surgical repair of long-gap esophageal atresia: A retrospective study comparing the management of long-gap esophageal atresia in the Nordic countries.


Journal

Journal of pediatric surgery
ISSN: 1531-5037
Titre abrégé: J Pediatr Surg
Pays: United States
ID NLM: 0052631

Informations de publication

Date de publication:
Mar 2019
Historique:
received: 02 02 2018
revised: 03 07 2018
accepted: 31 07 2018
pubmed: 18 9 2018
medline: 22 3 2019
entrez: 18 9 2018
Statut: ppublish

Résumé

Several surgical procedures have been described in the reconstruction of long-gap esophageal atresia (LGEA). We reviewed the surgical methods used in children with LGEA in the Nordic countries over a 15-year period and the postoperative complications within the first postoperative year. Retrospective multicenter medical record review of all children born with Gross type A or B esophageal atresia between 01/01/2000 and 12/31/2014 reconstructed within their first year of life. We included 71 children; 56 had Gross type A and 15 type B LGEA. Delayed primary anastomosis (DPA) was performed in 52.1% and an esophageal replacement procedure in 47.9%. Gastric pull-up (GPU) was the most frequent procedure (25.4%). The frequency of chromosomal abnormalities, congenital heart defects and other anomalies was significantly higher in patients who had a replacement procedure. The frequency of gastroesophageal reflux (GER) was significantly higher after DPA compared to esophageal replacement (p = 0.013). At 1-year follow-up the mean body weight was higher after DPA than after organ interposition (p = 0.043). DPA and esophageal replacement procedures were equally applied. Postoperative complications and follow-up were similar except for the development of GER and the body weight at 1-year follow-up. Long-term results should be investigated. Treatment study. Level III.

Sections du résumé

BACKGROUND BACKGROUND
Several surgical procedures have been described in the reconstruction of long-gap esophageal atresia (LGEA). We reviewed the surgical methods used in children with LGEA in the Nordic countries over a 15-year period and the postoperative complications within the first postoperative year.
METHODS METHODS
Retrospective multicenter medical record review of all children born with Gross type A or B esophageal atresia between 01/01/2000 and 12/31/2014 reconstructed within their first year of life.
RESULTS RESULTS
We included 71 children; 56 had Gross type A and 15 type B LGEA. Delayed primary anastomosis (DPA) was performed in 52.1% and an esophageal replacement procedure in 47.9%. Gastric pull-up (GPU) was the most frequent procedure (25.4%). The frequency of chromosomal abnormalities, congenital heart defects and other anomalies was significantly higher in patients who had a replacement procedure. The frequency of gastroesophageal reflux (GER) was significantly higher after DPA compared to esophageal replacement (p = 0.013). At 1-year follow-up the mean body weight was higher after DPA than after organ interposition (p = 0.043).
CONCLUSION CONCLUSIONS
DPA and esophageal replacement procedures were equally applied. Postoperative complications and follow-up were similar except for the development of GER and the body weight at 1-year follow-up. Long-term results should be investigated.
TYPE OF STUDY METHODS
Treatment study.
LEVEL OF EVIDENCE METHODS
Level III.

Identifiants

pubmed: 30220451
pii: S0022-3468(18)30512-8
doi: 10.1016/j.jpedsurg.2018.07.023
pii:
doi:

Types de publication

Journal Article Multicenter Study

Langues

eng

Sous-ensembles de citation

IM

Pagination

423-428

Informations de copyright

Copyright © 2018 Elsevier Inc. All rights reserved.

Auteurs

Tatjana Stadil (T)

Surgical Department A, Odense University Hospital, Odense, Denmark. Electronic address: Tatjana.stadil@rsyd.dk.

Antti Koivusalo (A)

Dept. of Pediatric Surgery, Children's Hospital, University of Helsinki, Helsinki, Finland. Electronic address: Antti.Koivusalo@hus.fi.

Mikko Pakarinen (M)

Dept. of Pediatric Surgery, Children's Hospital, University of Helsinki, Helsinki, Finland. Electronic address: Mikko.Pakarinen@hus.fi.

Audun Mikkelsen (A)

Dept. of Gastric and Pediatric Surgery, Oslo University Hospital, Rikshospitalet and Ullevål, Oslo, Norway. Electronic address: Audun.mikkelsen@medisin.uio.no.

Ragnhild Emblem (R)

Dept. of Gastric and Pediatric Surgery, Oslo University Hospital, Rikshospitalet and Ullevål, Oslo, Norway. Electronic address: Remblem@ous-hf.no.

Jan F Svensson (JF)

Department of Pediatric Surgery, Karolinska University Hospital and Department of Women's and Children's Health, Karolinska Institute, Stockholm, Sweden. Electronic address: Jan.f.svensson@sll.se.

Henrik Ehrén (H)

Department of Pediatric Surgery, Karolinska University Hospital and Department of Women's and Children's Health, Karolinska Institute, Stockholm, Sweden. Electronic address: Henrik.ehren@karolinska.sll.se.

Linus Jönsson (L)

Department of Pediatric Surgery, Queen Silvia Children's Hospital, Gothenburg, Sweden. Electronic address: Linus.jonsson@vgregion.se.

Jakob Bäckstrand (J)

Department of Pediatric Surgery, Queen Silvia Children's Hospital, Gothenburg, Sweden. Electronic address: Jakob.backstrand@vgregion.se.

Helene Engstrand Lilja (HE)

Department of Pediatric Surgery, Children's Hospital and Department of Women's and Children's Health, Uppsala University, Uppsala, Sweden. Electronic address: Helene.lilja@kbh.uu.se.

Felipe Donoso (F)

Department of Pediatric Surgery, Children's Hospital and Department of Women's and Children's Health, Uppsala University, Uppsala, Sweden. Electronic address: Felipe.donoso@kbh.uu.se.

Jørgen Mogens Thorup (JM)

Dept. of Pediatric Surgery, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark. Electronic address: Joergen.mogens.thorup@regionh.dk.

Thorstein Sæter (T)

Dept. of Pediatric Surgery, St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway. Electronic address: Thorstein.Seter@stolav.no.

Lars Rasmussen (L)

Surgical Department A, Odense University Hospital, Odense, Denmark. Electronic address: Lars.Rasmussen@rsyd.dk.

Rikke Neess Pedersen (RN)

Hans Christian Andersen Children's Hospital, Odense University Hospital, Odense, Denmark. Electronic address: Rikke.Neess.Pedersen@rsyd.dk.

Pernilla Stenström (P)

Dept. of Pediatrics, Children's Hospital, Lund University, Lund, Sweden. Electronic address: Pernilla.stenstrom@med.lu.se.

Einar Arnbjörnsson (E)

Dept. of Pediatrics, Children's Hospital, Lund University, Lund, Sweden. Electronic address: Einar.arnbjornsson@telia.com.

Kristján Óskarsson (K)

Children's Hospital, University Hospital, Reykjavik, Iceland. Electronic address: Kristosk@landspitali.is.

Niels Qvist (N)

Surgical Department A, Odense University Hospital, Odense, Denmark; Hans Christian Andersen Children's Hospital, Odense University Hospital, Odense, Denmark; OPEN, Odense Patient data Explorative Network, Odense University Hospital, Odense, Denmark. Electronic address: Niels.qvist@rsyd.dk.

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