CT Reconstruction Levels Affect Automated and Reader-Based ASPECTS Ratings in Acute Ischemic Stroke.


Journal

Journal of neuroimaging : official journal of the American Society of Neuroimaging
ISSN: 1552-6569
Titre abrégé: J Neuroimaging
Pays: United States
ID NLM: 9102705

Informations de publication

Date de publication:
01 2019
Historique:
received: 06 07 2018
revised: 03 09 2018
accepted: 04 09 2018
pubmed: 20 9 2018
medline: 5 3 2020
entrez: 20 9 2018
Statut: ppublish

Résumé

We investigated whether automated and reader-based ASPECTS in acute stroke patients are affected by different CT image reconstruction algorithms. ASPECTS were assessed by commercial software and four independent blinded readers (two residents and two consultants) from different CT reconstructions (filtered back projection and two different iterative reconstruction [IR] levels) in 43 acute stroke patients with proximal middle cerebral artery occlusion. Ground truth was provided by an expert with unrestricted data access. The residents showed significant variations between IR levels and had a significantly lower internal consistency across different reconstructions compared to the software, which performed similarly to the consultants. The consultant as well as the software also showed different deviations from ground truth with different IR levels, which were least at IR strength level 2. CT image postprocessing affects either automated or human ASPECTS in acute stroke patients. This effect was most pronounced in the less experienced readers, while the software had the most robust performance.

Sections du résumé

BACKGROUND AND PURPOSE
We investigated whether automated and reader-based ASPECTS in acute stroke patients are affected by different CT image reconstruction algorithms.
METHODS
ASPECTS were assessed by commercial software and four independent blinded readers (two residents and two consultants) from different CT reconstructions (filtered back projection and two different iterative reconstruction [IR] levels) in 43 acute stroke patients with proximal middle cerebral artery occlusion. Ground truth was provided by an expert with unrestricted data access.
RESULTS
The residents showed significant variations between IR levels and had a significantly lower internal consistency across different reconstructions compared to the software, which performed similarly to the consultants. The consultant as well as the software also showed different deviations from ground truth with different IR levels, which were least at IR strength level 2.
CONCLUSIONS
CT image postprocessing affects either automated or human ASPECTS in acute stroke patients. This effect was most pronounced in the less experienced readers, while the software had the most robust performance.

Identifiants

pubmed: 30230091
doi: 10.1111/jon.12562
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

62-64

Informations de copyright

© 2018 by the American Society of Neuroimaging.

Auteurs

Fatih Seker (F)

Department of Neuroradiology at Heidelberg University Hospital, Heidelberg, Germany.

Johannes Pfaff (J)

Department of Neuroradiology at Heidelberg University Hospital, Heidelberg, Germany.

Simon Nagel (S)

Department of Neurology at Heidelberg University Hospital, Heidelberg, Germany.

Dominik Vollherbst (D)

Department of Neuroradiology at Heidelberg University Hospital, Heidelberg, Germany.

Stephen Gerry (S)

Centre for Statistics in Medicine, University of Oxford, Oxford, UK.

Markus A Möhlenbruch (MA)

Department of Neuroradiology at Heidelberg University Hospital, Heidelberg, Germany.

Martin Bendszus (M)

Department of Neuroradiology at Heidelberg University Hospital, Heidelberg, Germany.

Christian Herweh (C)

Department of Neuroradiology at Heidelberg University Hospital, Heidelberg, Germany.

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