Impact of Surgeon's Experience on Vascular and Haemorrhagic Complications After Kidney Transplantation.


Journal

European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery
ISSN: 1532-2165
Titre abrégé: Eur J Vasc Endovasc Surg
Pays: England
ID NLM: 9512728

Informations de publication

Date de publication:
01 2019
Historique:
received: 08 11 2017
accepted: 24 07 2018
pubmed: 22 9 2018
medline: 20 6 2019
entrez: 22 9 2018
Statut: ppublish

Résumé

The aim of this study was to investigate the independent risk factors of vascular and haemorrhagic complications after kidney transplantation (KTx) and to evaluate how the surgeon's experience affects the rate of vascular and haemorrhagic complications. After exclusion of paediatric and multi-organ transplantations, 1462 KTx operations between 2000 and 2016 were analysed. Independent risk factors were evaluated by multivariable logistic regression analysis. The generalised estimating equation logit model was used to display learning curve progression and determine the best cut off number of KTx operations to reduce vascular and haemorrhagic complications. Vascular and haemorrhagic complications occurred in 38 KTx cases (2.6%). Renal vein thrombosis was the most common complication (0.6%). Graft loss occurred in 11 of 38 (28.9%) cases. Donor age of >60 years (OR 3.687, 95% CI 1.663-8.175, p = 0.001), recipient cardiovascular disease (CVD) (OR 2.270, 95% CI 1.071-4.810, p = 0.032), and surgeon's experience (OR 0.875, 95% CI 0.783-0.977, p = 0.018) were independent predictors of vascular and haemorrhagic complications. Twenty-six previous KTx operations are needed to decrease predicted probability of post-KTx vascular and haemorrhagic complications below 2.6%. The surgeon's experience is an independent risk factor for vascular and haemorrhagic complications after KTx. Acceptable post-operative vascular and haemorrhagic complications are achieved after a minimum of 26 KTx. As a donor age of >60 years and recipient CVD are also independent risk factors for vascular and haemorrhagic complications, it is suggested that these patients should preferably be operated on by surgeons who have performed more than 26 KTx operations.

Identifiants

pubmed: 30236441
pii: S1078-5884(18)30520-3
doi: 10.1016/j.ejvs.2018.07.041
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

139-149

Informations de copyright

Copyright © 2018 European Society for Vascular Surgery. Published by Elsevier B.V. All rights reserved.

Auteurs

Yakup Kulu (Y)

Department of General, Visceral, and Transplantation Surgery, University of Heidelberg, Heidelberg, Germany.

Parham Fathi (P)

Department of General, Visceral, and Transplantation Surgery, University of Heidelberg, Heidelberg, Germany.

Mohammad Golriz (M)

Department of General, Visceral, and Transplantation Surgery, University of Heidelberg, Heidelberg, Germany.

Elias Khajeh (E)

Department of General, Visceral, and Transplantation Surgery, University of Heidelberg, Heidelberg, Germany.

Mohammadsadegh Sabagh (M)

Department of General, Visceral, and Transplantation Surgery, University of Heidelberg, Heidelberg, Germany.

Omid Ghamarnejad (O)

Department of General, Visceral, and Transplantation Surgery, University of Heidelberg, Heidelberg, Germany.

Markus Mieth (M)

Department of General, Visceral, and Transplantation Surgery, University of Heidelberg, Heidelberg, Germany.

Alexis Ulrich (A)

Department of General, Visceral, and Transplantation Surgery, University of Heidelberg, Heidelberg, Germany.

Thilo Hackert (T)

Department of General, Visceral, and Transplantation Surgery, University of Heidelberg, Heidelberg, Germany.

Beat P Müller-Stich (BP)

Department of General, Visceral, and Transplantation Surgery, University of Heidelberg, Heidelberg, Germany.

Oliver Strobel (O)

Department of General, Visceral, and Transplantation Surgery, University of Heidelberg, Heidelberg, Germany.

Christoph Michalski (C)

Department of General, Visceral, and Transplantation Surgery, University of Heidelberg, Heidelberg, Germany.

Christian Morath (C)

Department of Nephrology, Heidelberg University Hospital, Heidelberg, Germany.

Martin Zeier (M)

Department of Nephrology, Heidelberg University Hospital, Heidelberg, Germany.

Markus W Büchler (MW)

Department of General, Visceral, and Transplantation Surgery, University of Heidelberg, Heidelberg, Germany.

Arianeb Mehrabi (A)

Department of General, Visceral, and Transplantation Surgery, University of Heidelberg, Heidelberg, Germany. Electronic address: arianeb_mehrabi@med.uni-heidelberg.de.

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Classifications MeSH