Influence of nanoporosity on the nature of hydroxyapatite formed on bioactive calcium silicate model glass.

bioactive glass biomaterial hydroxyapatite formation hydroxyapatite microstructure nanoporosity

Journal

Journal of biomedical materials research. Part B, Applied biomaterials
ISSN: 1552-4981
Titre abrégé: J Biomed Mater Res B Appl Biomater
Pays: United States
ID NLM: 101234238

Informations de publication

Date de publication:
05 2019
Historique:
received: 29 01 2018
revised: 24 05 2018
accepted: 28 05 2018
pubmed: 30 9 2018
medline: 15 7 2020
entrez: 30 9 2018
Statut: ppublish

Résumé

For hard tissue regeneration, the bioactivity of a material is measured by its ability to induce the formation of hydroxyapatite (HA) under physiological conditions. It depends on the dissolution behavior of the glass, which itself is determined by the composition and structure of glass. The enhanced HA growth on nanoporous than on nonporous glass has been attributed by some to greater specific surface area (SSA), but to nanopore size distribution by others. To decouple the influence of nanopore size and SSA on HA formation, we have successfully fabricated homogeneous 30CaO-70SiO

Identifiants

pubmed: 30267633
doi: 10.1002/jbm.b.34184
doi:

Substances chimiques

Calcium Compounds 0
Silicates 0
Durapatite 91D9GV0Z28
calcium silicate S4255P4G5M

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

886-899

Subventions

Organisme : International Materials Institute for New Functionality in Glass
ID : DMR-0844014
Pays : International
Organisme : National Science Foundation (PFI:AIR-TT)
ID : IIP-1602057
Pays : International

Informations de copyright

© 2018 Wiley Periodicals, Inc.

Auteurs

Ukrit Thamma (U)

Department of Materials Science and Engineering, Lehigh University, Bethlehem, 18015, Pennsylvania.

Tia Kowal (T)

Department of Biological Sciences, Lehigh University, Bethlehem, 18015, Pennsylvania.

Matthias Falk (M)

Department of Biological Sciences, Lehigh University, Bethlehem, 18015, Pennsylvania.

Himanshu Jain (H)

Department of Materials Science and Engineering, Lehigh University, Bethlehem, 18015, Pennsylvania.

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Classifications MeSH