Emergence of a carbapenem-resistant and colistin-heteroresistant Enterobacter cloacae clinical isolate in Japan.
Aged
Anti-Bacterial Agents
/ pharmacology
Bacterial Proteins
/ genetics
Carbapenems
/ pharmacology
Colistin
/ pharmacology
Diarrhea
/ drug therapy
Drug Resistance, Multiple, Bacterial
/ genetics
Enterobacter cloacae
/ genetics
Enterobacteriaceae Infections
/ drug therapy
Feces
/ microbiology
Female
Humans
Japan
Microbial Sensitivity Tests
Mutation
beta-Lactamases
/ genetics
Carbapenem resistance
Class C β-lactamase ACT-2
Colistin heteroresistance
Enterobacter cloacae
Journal
Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy
ISSN: 1437-7780
Titre abrégé: J Infect Chemother
Pays: Netherlands
ID NLM: 9608375
Informations de publication
Date de publication:
Apr 2019
Apr 2019
Historique:
received:
09
03
2018
revised:
08
08
2018
accepted:
04
09
2018
pubmed:
4
10
2018
medline:
18
6
2019
entrez:
4
10
2018
Statut:
ppublish
Résumé
A carbapenem-resistant and colistin-heteroresistant clinical isolate of Enterobacter cloacae was obtained from an inpatient in Okinawa, Japan. The minimum inhibitory concentrations of both imipenem and meropenem were 32 μg/mL. The isolate showed heteroresistance to colistin using the Etest method and resistance to colistin using the broth microdilution method. It had a disrupted ompC and a mutation in the promoter region of bla
Identifiants
pubmed: 30279112
pii: S1341-321X(18)30305-2
doi: 10.1016/j.jiac.2018.09.004
pii:
doi:
Substances chimiques
Anti-Bacterial Agents
0
Bacterial Proteins
0
Carbapenems
0
AmpC beta-lactamases
EC 3.5.2.6
beta-Lactamases
EC 3.5.2.6
Colistin
Z67X93HJG1
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
285-288Informations de copyright
Copyright © 2018. Published by Elsevier Ltd.