Assessment of tumour response after stereotactic ablative radiation therapy for lung cancer: A prospective quantitative hybrid

Adult Aged Aged, 80 and over Biomarkers, Tumor / analysis Carcinoma, Non-Small-Cell Lung / diagnostic imaging Female Fluorodeoxyglucose F18 Humans Lung Neoplasms / diagnostic imaging Male Middle Aged Neoplasm Staging Positron Emission Tomography Computed Tomography Prospective Studies Radiographic Image Interpretation, Computer-Assisted Radiosurgery / methods Treatment Outcome
CT perfusion dynamic 18F-FDG-PET kinetic modelling stereotactic ablative radiation therapy tumour monitoring

Journal

Journal of medical imaging and radiation oncology
ISSN: 1754-9485
Titre abrégé: J Med Imaging Radiat Oncol
Pays: Australia
ID NLM: 101469340

Informations de publication

Date de publication:
Feb 2019
Historique:
received: 16 05 2018
accepted: 25 08 2018
pubmed: 4 10 2018
medline: 5 3 2019
entrez: 4 10 2018
Statut: ppublish

Résumé

Stereotactic ablative radiotherapy (SABR) is a guideline-recommended treatment for inoperable stage I non-small cell lung cancer (NSCLC), but imaging assessment of response after SABR is difficult. The goal of this study was to evaluate imaging-based biomarkers of tumour response using dynamic Thirty-one patients with early-stage NSCLC participated in this prospective correlative study. Each underwent dynamic Tumour size changed only slightly after SABR (median 26 mm pre-SABR vs. 23 mm post-SABR; P = 0.01). However, dynamic Hybrid

Identifiants

DOI: 10.1111/1754-9485.12807 PMID: 30281918
pubmed: 30281918
doi: 10.1111/1754-9485.12807
doi:

Substances chimiques

Biomarkers, Tumor 0
Fluorodeoxyglucose F18 0Z5B2CJX4D

Types de publication

Clinical Trial, Phase II Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

94-101

Subventions

Organisme : Clinician-Scientist Grant
Organisme : Ontario Institute for Cancer Research

Informations de copyright

© 2018 The Royal Australian and New Zealand College of Radiologists.

Auteurs

Dae-Myoung Yang (DM)

Department of Medical Biophysics, Western University, London, Ontario, Canada.
Robarts Research Institute, Western University, London, Ontario, Canada.
Lawson Health Research Institute, London, Ontario, Canada.
ORCID: 0000-0002-1229-7759

David Palma (D)

Department of Oncology, Western University, London, Ontario, Canada.
Department of Radiation Oncology, London Regional Cancer Program, London, Ontario, Canada.

Alexander Louie (A)

Department of Oncology, Western University, London, Ontario, Canada.
Department of Radiation Oncology, London Regional Cancer Program, London, Ontario, Canada.

Richard Malthaner (R)

Department of Surgery, Division of Thoracic Surgery, London Health Sciences Centre, London, Ontario, Canada.

Dalilah Fortin (D)

Department of Surgery, Division of Thoracic Surgery, London Health Sciences Centre, London, Ontario, Canada.

George Rodrigues (G)

Department of Oncology, Western University, London, Ontario, Canada.
Department of Radiation Oncology, London Regional Cancer Program, London, Ontario, Canada.

Brian Yaremko (B)

Department of Oncology, Western University, London, Ontario, Canada.
Department of Radiation Oncology, London Regional Cancer Program, London, Ontario, Canada.
ORCID: 0000-0002-5055-9027

Joanna Laba (J)

Department of Oncology, Western University, London, Ontario, Canada.
Department of Radiation Oncology, London Regional Cancer Program, London, Ontario, Canada.

Stewart Gaede (S)

Department of Medical Biophysics, Western University, London, Ontario, Canada.
Department of Oncology, Western University, London, Ontario, Canada.
Department of Engineering and Physics, Western University, London, Ontario, Canada.

Andrew Warner (A)

Department of Radiation Oncology, London Regional Cancer Program, London, Ontario, Canada.

Richard Inculet (R)

Department of Surgery, Division of Thoracic Surgery, London Health Sciences Centre, London, Ontario, Canada.

Ting-Yim Lee (TY)

Department of Medical Biophysics, Western University, London, Ontario, Canada.
Robarts Research Institute, Western University, London, Ontario, Canada.
Lawson Health Research Institute, London, Ontario, Canada.

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Classifications MeSH

questionsmedicales.fr › Personnes › Tranches d'âge › Adulte › Assessment of tumour response after...
questionsmedicales.fr › Personnes › Tranches d'âge › Adulte › Sujet âgé › Assessment of tumour response after...
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questionsmedicales.fr › Maladies de l'appareil respiratoire › Tumeurs de l'appareil respiratoire › Tumeurs du poumon › Tumeurs des bronches › Carcinome bronchogénique › Carcinome pulmonaire non à petites cellules › Assessment of tumour response after...
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