Antifungal efficacy of photodynamic therapy with TONS 504 for pathogenic filamentous fungi.
Aspergillus fumigatus
Chlorin derivative
Filamentous fungi
Fungal keratitis
Fusarium solani
Photodynamic antimicrobial chemotherapy (PACT)
Journal
Lasers in medical science
ISSN: 1435-604X
Titre abrégé: Lasers Med Sci
Pays: England
ID NLM: 8611515
Informations de publication
Date de publication:
Jun 2019
Jun 2019
Historique:
received:
13
08
2018
accepted:
27
09
2018
pubmed:
5
10
2018
medline:
6
7
2019
entrez:
5
10
2018
Statut:
ppublish
Résumé
The pathogenic filamentous fungi Fusarium solani (F. solani) and Aspergillus fumigatus (A. fumigatus) are common causes of fungal keratitis. We have here evaluated the antifungal efficacy of photodynamic antimicrobial chemotherapy (PACT) with the novel chlorin derivative TONS 504 and a light-emitting diode (LED) with a wavelength of 660 nm for these fungal species. Isolated fungal spores were irradiated at LED energies of 10, 20, or 30 J/cm
Identifiants
pubmed: 30284654
doi: 10.1007/s10103-018-2654-y
pii: 10.1007/s10103-018-2654-y
doi:
Substances chimiques
Antifungal Agents
0
Photosensitizing Agents
0
Porphyrins
0
TONS504
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
743-747Subventions
Organisme : Japan Society for the Promotion of Science (JP)
ID : 15K10894, 18K09411
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