Dermal CD207-Negative Migratory Dendritic Cells Are Fully Competent to Prime Protective, Skin Homing Cytotoxic T-Lymphocyte Responses.

Animals CD8-Positive T-Lymphocytes / immunology Cross-Priming Disease Models, Animal Epitopes, T-Lymphocyte / genetics Histocompatibility Antigens Class I / immunology Humans Immunologic Memory Langerhans Cells / immunology Mice Mice, Transgenic Skin / cytology Skin Diseases, Viral / immunology T-Lymphocytes, Cytotoxic / immunology Vaccinia virus / immunology

Journal

The Journal of investigative dermatology
ISSN: 1523-1747
Titre abrégé: J Invest Dermatol
Pays: United States
ID NLM: 0426720

Informations de publication

Date de publication:
02 2019
Historique:
received: 30 04 2018
revised: 14 08 2018
accepted: 28 08 2018
pubmed: 9 10 2018
medline: 1 1 2020
entrez: 9 10 2018
Statut: ppublish

Résumé

Dendritic cells (DCs) are important inducers and regulators of T-cell responses. They are able to activate and modulate the differentiation of CD4

Identifiants

DOI: 10.1016/j.jid.2018.08.022 PMID: 30296420
pubmed: 30296420
pii: S0022-202X(18)32650-2
doi: 10.1016/j.jid.2018.08.022
pii:
doi:

Substances chimiques

Epitopes, T-Lymphocyte 0
Histocompatibility Antigens Class I 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

422-429

Informations de copyright

Copyright © 2018 The Authors. Published by Elsevier Inc. All rights reserved.

Auteurs

Tobias Hain (T)

Institute for Immunology, University Medical Center Mainz, Germany; Research Centre for Immunotherapy, University Medical Center Mainz, Mainz, Germany.

Felix Melchior (F)

Institute for Immunology, University Medical Center Mainz, Germany; Research Centre for Immunotherapy, University Medical Center Mainz, Mainz, Germany.

Nadine Kamenjarin (N)

Institute for Immunology, University Medical Center Mainz, Germany; Research Centre for Immunotherapy, University Medical Center Mainz, Mainz, Germany.

Sabine Muth (S)

Institute for Immunology, University Medical Center Mainz, Germany; Research Centre for Immunotherapy, University Medical Center Mainz, Mainz, Germany.

Hela Weslati (H)

Institute for Immunology, University Medical Center Mainz, Germany; Research Centre for Immunotherapy, University Medical Center Mainz, Mainz, Germany.

Björn E Clausen (BE)

Research Centre for Immunotherapy, University Medical Center Mainz, Mainz, Germany; Institute for Molecular Medicine, University Medical Center Mainz, Mainz, Germany.

Karsten Mahnke (K)

Department of Dermatology, Ruprecht-Karls-University Heidelberg, Heidelberg, Germany.

Cinthia Silva-Vilches (C)

Department of Dermatology, Ruprecht-Karls-University Heidelberg, Heidelberg, Germany.

Kristian Schütze (K)

Institute for Immunology, University Medical Center Mainz, Germany; Research Centre for Immunotherapy, University Medical Center Mainz, Mainz, Germany.

Julian Sohl (J)

Research Centre for Immunotherapy, University Medical Center Mainz, Mainz, Germany; Third Department of Medicine-Hematology, Oncology, Pneumology, University Medical Center Mainz, Mainz, Germany.

Markus P Radsak (MP)

Research Centre for Immunotherapy, University Medical Center Mainz, Mainz, Germany; Third Department of Medicine-Hematology, Oncology, Pneumology, University Medical Center Mainz, Mainz, Germany.

Georg Bündgen (G)

Institute for Immunology, University Medical Center Mainz, Germany; Research Centre for Immunotherapy, University Medical Center Mainz, Mainz, Germany.

Tobias Bopp (T)

Institute for Immunology, University Medical Center Mainz, Germany; Research Centre for Immunotherapy, University Medical Center Mainz, Mainz, Germany.

Sven Danckwardt (S)

Posttranscriptional Gene Regulation and Experimental Hemostasis, University Medical Center Mainz, Mainz, Germany; Institute for Clinical Chemistry and Laboratory Medicine, University Medical Center Mainz, Mainz, Germany; Center for Thrombosis and Hemostasis, University Medical Center Mainz, Mainz, Germany.

Hansjörg Schild (H)

Institute for Immunology, University Medical Center Mainz, Germany; Research Centre for Immunotherapy, University Medical Center Mainz, Mainz, Germany.

Hans Christian Probst (HC)

Institute for Immunology, University Medical Center Mainz, Germany; Research Centre for Immunotherapy, University Medical Center Mainz, Mainz, Germany. Electronic address: hcprobst@uni-mainz.de.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Dermal CD207-Negative Migratory Dendritic...
questionsmedicales.fr › Systèmes sanguin et immunitaire › Système immunitaire › Leucocytes › Agranulocytes › Lymphocytes › Lymphocytes T › Lymphocytes T CD8+ › Dermal CD207-Negative Migratory Dendritic...
questionsmedicales.fr › Phénomènes du système immunitaire › Activation des lymphocytes › Cross-priming › Dermal CD207-Negative Migratory Dendritic...
questionsmedicales.fr › Techniques d'investigation › Modèles théoriques › Modèles biologiques › Modèles animaux de maladie humaine › Dermal CD207-Negative Migratory Dendritic...
questionsmedicales.fr › Facteurs biologiques › Antigènes › Épitopes › Déterminants antigéniques des lymphocytes T › Dermal CD207-Negative Migratory Dendritic...
questionsmedicales.fr › Facteurs biologiques › Antigènes › Isoantigènes › Antigènes d'histocompatibilité › Antigènes d'histocompatibilité de classe I › Dermal CD207-Negative Migratory Dendritic...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Dermal CD207-Negative Migratory Dendritic...
questionsmedicales.fr › Phénomènes du système immunitaire › Immunité › Immunité acquise › Mémoire immunologique › Dermal CD207-Negative Migratory Dendritic...
questionsmedicales.fr › Systèmes sanguin et immunitaire › Système immunitaire › Système phagocytaire mononucléé › Cellules dendritiques › Cellules de Langerhans › Dermal CD207-Negative Migratory Dendritic...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Dermal CD207-Negative Migratory Dendritic...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Souris transgéniques › Dermal CD207-Negative Migratory Dendritic...
questionsmedicales.fr › Système tégumentaire › Peau › Dermal CD207-Negative Migratory Dendritic...
questionsmedicales.fr › Maladies de la peau et du tissu conjonctif › Maladies de la peau › Infections de la peau › Dermatoses virales › Dermal CD207-Negative Migratory Dendritic...
questionsmedicales.fr › Systèmes sanguin et immunitaire › Système immunitaire › Leucocytes › Agranulocytes › Lymphocytes › Lymphocytes T › Sous-populations de lymphocytes T › Lymphocytes T cytotoxiques › Dermal CD207-Negative Migratory Dendritic...
questionsmedicales.fr › Virus › Virus à ADN › Poxviridae › Chordopoxvirinae › Orthopoxvirus › Virus de la vaccine › Dermal CD207-Negative Migratory Dendritic...