Role of rare earth elements in methanol oxidation.


Journal

Current opinion in chemical biology
ISSN: 1879-0402
Titre abrégé: Curr Opin Chem Biol
Pays: England
ID NLM: 9811312

Informations de publication

Date de publication:
04 2019
Historique:
received: 12 07 2018
revised: 05 09 2018
accepted: 21 09 2018
pubmed: 12 10 2018
medline: 18 12 2019
entrez: 12 10 2018
Statut: ppublish

Résumé

For decades rare earth elements (or lanthanides) were considered not to be involved in biological processes, until their discovery in the active site of the XoxF-type methanol dehydrogenase of the methanotrophic bacterium Methylacidiphilum fumariolicum SolV. Follow-up studies revealed the presence of lanthanides in other pyrroloquinoline quinone-containing enzymes involved in alcohol metabolism. This review discusses the biochemistry of the lanthanide-dependent enzymes and the ability of these metals of influencing the gene expression and the type of methanol dehydrogenase used by microorganisms. Furthermore, it highlights novel insights on the uptake mechanism of rare earth elements into bacterial cells.

Identifiants

pubmed: 30308436
pii: S1367-5931(18)30095-4
doi: 10.1016/j.cbpa.2018.09.019
pii:
doi:

Substances chimiques

7-(1-hydroxy-1-methyl-3-(thien-3-yl)propyl)-6,14-ethanotetrahydrooripavine 0
Lanthanoid Series Elements 0
Metals, Rare Earth 0
Etorphine 42M2Y6NU9O
Methanol Y4S76JWI15

Types de publication

Journal Article Research Support, Non-U.S. Gov't Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

39-44

Subventions

Organisme : European Research Council
ID : 669371
Pays : International

Informations de copyright

Copyright © 2018 The Authors. Published by Elsevier Ltd.. All rights reserved.

Auteurs

Nunzia Picone (N)

Department of Microbiology, IWWR, Radboud University, Heyendaalseweg 135, 6525 AJ Nijmegen, The Netherlands.

Huub Jm Op den Camp (HJ)

Department of Microbiology, IWWR, Radboud University, Heyendaalseweg 135, 6525 AJ Nijmegen, The Netherlands. Electronic address: h.opdencamp@science.ru.nl.

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Classifications MeSH