Investigating the Bioaccessibility and Bioavailability of Cadmium in a Cooked Rice Food Matrix by Using an 11-Day Rapid Caco-2/HT-29 Co-culture Cell Model Combined with an In Vitro Digestion Model.
Bioaccessibility
Bioavailability
Caco-2/HT-29 cells
Cadmium (Cd)
Co-culture
Cooked rice
Journal
Biological trace element research
ISSN: 1559-0720
Titre abrégé: Biol Trace Elem Res
Pays: United States
ID NLM: 7911509
Informations de publication
Date de publication:
Aug 2019
Aug 2019
Historique:
received:
29
08
2018
accepted:
15
10
2018
pubmed:
26
10
2018
medline:
6
2
2020
entrez:
26
10
2018
Statut:
ppublish
Résumé
Investigating the bioaccessibility and bioavailability of Cd based on real contaminated cooked rice matrixes helps establish an accurate risk assessment method and effectively reduce the digestion and absorption of Cd. An 11-day in vitro rapid Caco-2/HT-29 co-culture cell model was used to establish and evaluate the simulation of the absorption and transport of Cd in the small intestine with a 70:30 Caco-2/HT-29 co-culture ratio and 1.0 mmol L
Identifiants
pubmed: 30357757
doi: 10.1007/s12011-018-1554-0
pii: 10.1007/s12011-018-1554-0
doi:
Substances chimiques
Cadmium
00BH33GNGH
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
336-348Subventions
Organisme : the National Natural Science Foundation of China
ID : 31771981
Organisme : Natural Science Foundation of Hunan Province of China under Grant
ID : 2018JJ3877