Cryogen-free dissolution dynamic nuclear polarization polarizer operating at 3.35 T, 6.70 T, and 10.1 T.
dissolution dynamic nuclear polarization
dry magnet
hyperpolarization
polarizer
Journal
Magnetic resonance in medicine
ISSN: 1522-2594
Titre abrégé: Magn Reson Med
Pays: United States
ID NLM: 8505245
Informations de publication
Date de publication:
03 2019
03 2019
Historique:
received:
08
08
2018
revised:
26
08
2018
accepted:
27
08
2018
pubmed:
26
10
2018
medline:
18
3
2020
entrez:
26
10
2018
Statut:
ppublish
Résumé
A novel dissolution dynamic nuclear polarization (dDNP) polarizer platform is presented. The polarizer meets a number of key requirements for in vitro, preclinical, and clinical applications. It uses no liquid cryogens, operates in continuous mode, accommodates a wide range of sample sizes up to and including those required for human studies, and is fully automated. It offers a wide operational window both in terms of magnetic field, up to 10.1 T, and temperature, from room temperature down to 1.3 K. The polarizer delivers a We confirm the previously reported strong field dependence in the range 3.35 to 6.7 T, but see no further increase in polarization when increasing the magnetic field strength to 10.1 T for [1-
Substances chimiques
Helium
206GF3GB41
Pyruvic Acid
8558G7RUTR
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
2184-2194Subventions
Organisme : Danish Council for Independent Research
ID : 1323-00331B/00331A
Pays : International
Organisme : National Research Foundation
ID : DNRF-124
Pays : International
Organisme : Danish National Research Foundation
ID : DNRF-124
Pays : International
Informations de copyright
© 2018 International Society for Magnetic Resonance in Medicine.