Predictors of outcome in heart failure patients with severe functional mitral regurgitation undergoing MitraClip treatment.
Aged
Disease Progression
Echocardiography
Female
Follow-Up Studies
Heart Failure
/ complications
Heart Valve Prosthesis Implantation
/ methods
Humans
Incidence
Italy
/ epidemiology
Male
Mitral Valve
/ diagnostic imaging
Mitral Valve Insufficiency
/ diagnosis
Prognosis
Prospective Studies
Prosthesis Design
Risk Assessment
/ methods
Risk Factors
Severity of Illness Index
Survival Rate
/ trends
Treatment Outcome
Ventricular Function, Left
/ physiology
Atrial fibrillation
Cardiopulmonary exercise test
Functional mitral regurgitation
Heart failure
MitraClip
Percutaneous mitral valve repair
Journal
International journal of cardiology
ISSN: 1874-1754
Titre abrégé: Int J Cardiol
Pays: Netherlands
ID NLM: 8200291
Informations de publication
Date de publication:
01 06 2019
01 06 2019
Historique:
received:
23
04
2018
revised:
14
10
2018
accepted:
15
10
2018
pubmed:
27
10
2018
medline:
7
1
2020
entrez:
27
10
2018
Statut:
ppublish
Résumé
The prognostic predictors of outcome in patients with functional mitral regurgitation (FMR) undergoing MitraClip implantation (MCi) are still poorly known. The aim of our study is to identify the baseline predictors of outcome in FMR patients candidate to MCi. All patients with symptomatic moderate-to-severe or severe FMR undergoing MCi at our institution were consecutively and prospectively enrolled. Baseline clinical and instrumental data were collected. Primary endpoint was the occurrence of cardiac death; secondary endpoints were all-cause death and the composite of cardiac death or rehospitalization for heart failure. 74 patients (mean 71.6 ± 8.3 years) were enrolled. During follow-up (median 416.0 days), the primary endpoint occurred in 15 (20.3%), all-cause death in 26 (35.1%) and the composite endpoint in 25 (33.8%). At multivariate analysis, the left atrial volume index (LAVi; HR:1.02; P = 0.048) and the low peak oxygen uptake (peak VO Peak VO
Sections du résumé
BACKGROUND
The prognostic predictors of outcome in patients with functional mitral regurgitation (FMR) undergoing MitraClip implantation (MCi) are still poorly known. The aim of our study is to identify the baseline predictors of outcome in FMR patients candidate to MCi.
METHODS
All patients with symptomatic moderate-to-severe or severe FMR undergoing MCi at our institution were consecutively and prospectively enrolled. Baseline clinical and instrumental data were collected. Primary endpoint was the occurrence of cardiac death; secondary endpoints were all-cause death and the composite of cardiac death or rehospitalization for heart failure.
RESULTS
74 patients (mean 71.6 ± 8.3 years) were enrolled. During follow-up (median 416.0 days), the primary endpoint occurred in 15 (20.3%), all-cause death in 26 (35.1%) and the composite endpoint in 25 (33.8%). At multivariate analysis, the left atrial volume index (LAVi; HR:1.02; P = 0.048) and the low peak oxygen uptake (peak VO
CONCLUSIONS
Peak VO
Identifiants
pubmed: 30360995
pii: S0167-5273(18)32637-8
doi: 10.1016/j.ijcard.2018.10.055
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
50-58Informations de copyright
Copyright © 2018. Published by Elsevier B.V.