Graphene nanoplatelets in potentiometry: A nanocomposite carbon paste and PVC based membrane sensors for analysis of Vilazodone HCl in plasma and milk samples.


Journal

Talanta
ISSN: 1873-3573
Titre abrégé: Talanta
Pays: Netherlands
ID NLM: 2984816R

Informations de publication

Date de publication:
01 Feb 2019
Historique:
received: 06 07 2018
revised: 20 09 2018
accepted: 24 09 2018
entrez: 29 10 2018
pubmed: 29 10 2018
medline: 14 11 2018
Statut: ppublish

Résumé

Graphene is the ''new star'' material for electrochemical sensing. It has unique mechanical, thermal and electrical properties, in addition to its ultra light weight. In the present work we combine for the first time the special features offered by graphene and the advantages of ion selective potentiometric sensors in a single study. We propose two types of sensors, a graphene based carbon paste and a poly vinyl chloride (PVC) based membrane sensors for the analysis of Vilazodone hydrochloride in bulk, human plasma and formula milk samples. Electro active agent is an ion- association complex based on coupling of Vilazodone cationic cite with anionic cite of Molybdate ion in a ratio 1:1. Both sensors are evaluated according to the IUPAC recommendation data, revealing linear response in the concentration range 10

Identifiants

pubmed: 30368303
pii: S0039-9140(18)31009-9
doi: 10.1016/j.talanta.2018.09.091
pii:
doi:

Substances chimiques

Antidepressive Agents 0
Graphite 7782-42-5
Molybdenum 81AH48963U
Polyvinyl Chloride 9002-86-2
Diethylhexyl Phthalate C42K0PH13C
ammonium molybdate OGI154X474
Vilazodone Hydrochloride U8HTX2GK8J

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

9-14

Informations de copyright

Copyright © 2018 Elsevier B.V. All rights reserved.

Auteurs

Amira M El-Kosasy (AM)

Department of Pharmaceutical Analytical Chemistry, Faculty of Pharmacy, Ain Shams University, Cairo, Egypt.

Mona Hamdy Abdel Rahman (MH)

Department of Pharmaceutical Analytical Chemistry, Faculty of Pharmacy, Ain Shams University, Cairo, Egypt.

Sarah H Abdelaal (SH)

Department of Pharmaceutical Analytical Chemistry, Faculty of Pharmacy, Ain Shams University, Cairo, Egypt. Electronic address: sarah.hamdy19@gmail.com.

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Classifications MeSH