Exercise as a diagnostic and therapeutic tool for the prevention of cardiovascular dysfunction in breast cancer patients.
Adult
Anthracyclines
/ administration & dosage
Antineoplastic Combined Chemotherapy Protocols
/ adverse effects
Breast Neoplasms
/ diagnosis
Cardiorespiratory Fitness
Echocardiography, Doppler, Pulsed
Exercise Test
Exercise Therapy
Exercise Tolerance
/ drug effects
Female
Heart Diseases
/ chemically induced
Humans
Magnetic Resonance Imaging, Cine
Middle Aged
Oxygen Consumption
/ drug effects
Predictive Value of Tests
Primary Prevention
Prospective Studies
Risk Assessment
Risk Factors
Stroke Volume
/ drug effects
Treatment Outcome
Ventricular Function, Left
/ drug effects
Victoria
Exercise
cardiorespiratory fitness
cardiotoxicity
heart failure
survivorship
Journal
European journal of preventive cardiology
ISSN: 2047-4881
Titre abrégé: Eur J Prev Cardiol
Pays: England
ID NLM: 101564430
Informations de publication
Date de publication:
02 2019
02 2019
Historique:
pubmed:
31
10
2018
medline:
1
9
2020
entrez:
31
10
2018
Statut:
ppublish
Résumé
Anthracycline chemotherapy may be associated with decreased cardiac function and functional capacity measured as the peak oxygen uptake during exercise ( Twenty-eight patients with early stage breast cancer undergoing anthracycline chemotherapy were able to choose between exercise training (mean ± SD age 47 ± 9 years, n = 14) or usual care (mean ± SD age 53 ± 9 years, n = 14). Measurements performed before and after anthracycline chemotherapy included cardiopulmonary exercise testing to determine Decreases in The peak exercise cardiac output can identify patients at risk of chemotherapy-induced functional disability, whereas current clinical standards are unhelpful. Functional disability can be prevented with exercise training.
Sections du résumé
BACKGROUND
Anthracycline chemotherapy may be associated with decreased cardiac function and functional capacity measured as the peak oxygen uptake during exercise (
METHODS
Twenty-eight patients with early stage breast cancer undergoing anthracycline chemotherapy were able to choose between exercise training (mean ± SD age 47 ± 9 years, n = 14) or usual care (mean ± SD age 53 ± 9 years, n = 14). Measurements performed before and after anthracycline chemotherapy included cardiopulmonary exercise testing to determine
RESULTS
Decreases in
CONCLUSIONS
The peak exercise cardiac output can identify patients at risk of chemotherapy-induced functional disability, whereas current clinical standards are unhelpful. Functional disability can be prevented with exercise training.
Identifiants
pubmed: 30376366
doi: 10.1177/2047487318811181
doi:
Substances chimiques
Anthracyclines
0
Types de publication
Controlled Clinical Trial
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
305-315Commentaires et corrections
Type : CommentIn