Incidental thoracic findings in computed tomography scans before transcatheter aortic valve implantation.
Aged
Aged, 80 and over
Aortic Valve Stenosis
/ diagnostic imaging
Female
Heart Valve Prosthesis
Humans
Incidence
Incidental Findings
Lung Neoplasms
/ diagnostic imaging
Male
Proportional Hazards Models
Retrospective Studies
Solitary Pulmonary Nodule
/ diagnostic imaging
Survival Rate
Tomography, X-Ray Computed
Transcatheter Aortic Valve Replacement
Lung cancer
Solitary pulmonary nodule
Thoracic lymphadenopathy
Transcatheter aortic valve implantation
Journal
Interactive cardiovascular and thoracic surgery
ISSN: 1569-9285
Titre abrégé: Interact Cardiovasc Thorac Surg
Pays: England
ID NLM: 101158399
Informations de publication
Date de publication:
01 04 2019
01 04 2019
Historique:
received:
20
06
2018
revised:
10
09
2018
accepted:
16
09
2018
pubmed:
1
11
2018
medline:
13
11
2019
entrez:
1
11
2018
Statut:
ppublish
Résumé
Preoperative computed tomography (CT) scans for transcatheter aortic valve implantation (TAVI) are used routinely. In elderly high-risk patients, incidental radiographic findings are frequently reported. The aim of this study was to investigate the impact of auxiliary findings on the patients' mid-term survival, which might affect the treatment strategy. Between March 2011 and April 2016, all radiological reports of contrast-enhanced CT scans of 976 patients scheduled for TAVI were analysed retrospectively for incidental thoracic findings including solitary pulmonary nodules (SPN) and thoracic lymphadenopathy (LAP). The minimum follow-up period was 1 year after TAVI. The median age of all patients was 79 years; 51.9% (n = 507) were women. Approximately 37% (n = 361) of patients showed 1 of the determined findings. An SPN ≥5 mm was diagnosed in 16.4% (n = 160) of patients. Four of them developed lung cancer and 2 nodules were identified as metastases during follow-up. In addition, 12% (n = 117) of the patients had thoracic LAP. Whereas SPN had no significant effect on the overall survival rate, evidence of LAP turned out to be a statistically significant factor regarding 4-year survival (P = 0.001; hazard ratio 1.66; 95% confidence internal 1.19-2.31). SPN ≥5 mm were detected in 16.4% of patients scheduled for TAVI. Nevertheless, the incidence of lung cancer was low and the effect on survival in this high-risk group of patients was statistically not significant. In contrast, thoracic LAP had a significant negative effect on survival. It needs to be proven if the outcome of this cohort can be enhanced by further diagnostics and therapy.
Identifiants
pubmed: 30380069
pii: 5149802
doi: 10.1093/icvts/ivy299
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
559-565Informations de copyright
© The Author(s) 2018. Published by Oxford University Press on behalf of the European Association for Cardio-Thoracic Surgery. All rights reserved.