Antifungal susceptibility trend and analysis of resistance mechanism for Candida species isolated from bloodstream at a Japanese university hospital.
ATP-Binding Cassette Transporters
/ genetics
Amidines
/ pharmacology
Amino Acid Substitution
/ genetics
Antifungal Agents
/ pharmacology
Candida
/ drug effects
Candidemia
/ blood
Drug Resistance, Fungal
/ genetics
Fungal Proteins
/ genetics
Hospitals, University
Humans
Japan
Microbial Sensitivity Tests
ABC transporter
Antifungal susceptibility
Candida spp.
FKS mutation
Journal
Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy
ISSN: 1437-7780
Titre abrégé: J Infect Chemother
Pays: Netherlands
ID NLM: 9608375
Informations de publication
Date de publication:
Jan 2019
Jan 2019
Historique:
received:
21
08
2018
revised:
01
10
2018
accepted:
09
10
2018
pubmed:
8
11
2018
medline:
9
5
2019
entrez:
8
11
2018
Statut:
ppublish
Résumé
We compared the susceptibility of six commercially available antifungal agents (fluconazole, itraconazole, voriconazole, caspofungin, micafungin, and amphotericin B) against 133 Candida bloodstream isolates between 2008 and 2013 at Aichi Medical University Hospital. C. albicans was the most common isolate, followed by C. parapsilosis, C. glabrata, and C. tropicalis. MIC
Identifiants
pubmed: 30401513
pii: S1341-321X(18)30399-4
doi: 10.1016/j.jiac.2018.10.007
pii:
doi:
Substances chimiques
ATP-Binding Cassette Transporters
0
Amidines
0
Antifungal Agents
0
Fungal Proteins
0
T-2307
0
Types de publication
Comparative Study
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
34-40Informations de copyright
Copyright © 2018 Japanese Society of Chemotherapy and The Japanese Association for Infectious Diseases. Published by Elsevier Ltd. All rights reserved.