Identifying an isoflavone from the root of Pueraria lobata as a potent tyrosinase inhibitor.

Agaricales / drug effects Fungal Proteins / pharmacology Isoflavones / pharmacology Kinetics Molecular Docking Simulation Monophenol Monooxygenase / antagonists & inhibitors Plant Roots / chemistry Pueraria / chemistry
Calycosin Isoflavones Mushroom tyrosinase Pueraria lobata

Journal

Food chemistry
ISSN: 1873-7072
Titre abrégé: Food Chem
Pays: England
ID NLM: 7702639

Informations de publication

Date de publication:
15 Mar 2019
Historique:
received: 12 06 2018
revised: 04 09 2018
accepted: 02 10 2018
entrez: 10 11 2018
pubmed: 10 11 2018
medline: 20 2 2019
Statut: ppublish

Résumé

Traditionally, the root of Pueraria lobata are widely used as a functional food. It was observed that a 70% ethanol extract showed a dose-dependent inhibition towards mushroom tyrosinase. Among the different isolated compounds, calycosin demonstrated potent inhibitory activity against substrates l-tyrosine and l-DOPA, with IC

Identifiants

DOI: 10.1016/j.foodchem.2018.10.008 PMID: 30409609
pubmed: 30409609
pii: S0308-8146(18)31773-4
doi: 10.1016/j.foodchem.2018.10.008
pii:
doi:

Substances chimiques

Fungal Proteins 0
Isoflavones 0
7,3'-dihydroxy-4'-methoxyisoflavone 09N3E8P7TA
formononetin 295DQC67BJ
daidzein 6287WC5J2L
Monophenol Monooxygenase EC 1.14.18.1

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

383-389

Informations de copyright

Copyright © 2018 Elsevier Ltd. All rights reserved.

Auteurs

Aditi Wagle (A)

Department of Food and Life Science, Pukyong National University, Busan 48513, Republic of Korea.

Su Hui Seong (SH)

Department of Food and Life Science, Pukyong National University, Busan 48513, Republic of Korea.

Hyun Ah Jung (HA)

Department of Food Science and Human Nutrition, Chonbuk National University, Jeonju 54896, Republic of Korea. Electronic address: jungha@jbnu.ac.kr.

Jae Sue Choi (JS)

Department of Food and Life Science, Pukyong National University, Busan 48513, Republic of Korea. Electronic address: choijs@pknu.ac.kr.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Champignons › Basidiomycota › Agaricales › Identifying an isoflavone from the root of...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines fongiques › Identifying an isoflavone from the root of...
questionsmedicales.fr › Composés hétérocycliques › Composés hétérocycliques à cycles fusionnés › Composés hétérobicycliques › Benzopyranes › 4H-1-Benzopyran-4-ones › Flavonoïdes › Isoflavones › Identifying an isoflavone from the root of...
questionsmedicales.fr › Phénomènes chimiques › Phénomènes biochimiques › Cinétique › Identifying an isoflavone from the root of...
questionsmedicales.fr › Sciences de l'information › Méthodologies informatiques › Simulation numérique › Simulation de docking moléculaire › Identifying an isoflavone from the root of...
questionsmedicales.fr › Enzymes et coenzymes › Enzymes › Oxidoreductases › Oxygénases › Mixed function oxygenases › Catechol oxidase › Monophenol monooxygenase › Identifying an isoflavone from the root of...
questionsmedicales.fr › Structures de plante › Racines de plante › Identifying an isoflavone from the root of...
questionsmedicales.fr › Eucaryotes › Viridiplantae › Streptophyta › Embryophyta › Tracheobionta › Magnoliopsida › Fabaceae › Pueraria › Identifying an isoflavone from the root of...