Enterovirus A71 Infection Activates Human Immune Responses and Induces Pathological Changes in Humanized Mice.
enterovirus A71
human immune responses
humanized mice
Journal
Journal of virology
ISSN: 1098-5514
Titre abrégé: J Virol
Pays: United States
ID NLM: 0113724
Informations de publication
Date de publication:
01 02 2019
01 02 2019
Historique:
received:
19
06
2018
accepted:
05
11
2018
pubmed:
16
11
2018
medline:
9
11
2019
entrez:
16
11
2018
Statut:
epublish
Résumé
Since the discovery of enterovirus A71 (EV-A71) half a century ago, it has been recognized as the cause of large-scale outbreaks of hand-foot-and-mouth disease worldwide, particularly in the Asia-Pacific region, causing great concern for public health and economic burdens. Detailed mechanisms on the modulation of immune responses after EV-A71 infection have not been fully known, and the lack of appropriate models hinders the development of promising vaccines and drugs. In the present study, NOD-
Identifiants
pubmed: 30429352
pii: JVI.01066-18
doi: 10.1128/JVI.01066-18
pmc: PMC6340035
pii:
doi:
Substances chimiques
Inflammation Mediators
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Informations de copyright
Copyright © 2019 American Society for Microbiology.
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