Novel Pharmacotherapy for Hypertrophic Cardiomyopathy.

Adrenergic beta-Antagonists / therapeutic use Calcium Channel Blockers / therapeutic use Cardiomyopathy, Hypertrophic / drug therapy Cardiotonic Agents / therapeutic use Clinical Trials as Topic Forecasting Humans Off-Label Use Practice Guidelines as Topic
Clinical trials Hypertrophic cardiomyopathy Medical therapy Novel drug development

Journal

Cardiology clinics
ISSN: 1558-2264
Titre abrégé: Cardiol Clin
Pays: Netherlands
ID NLM: 8300331

Informations de publication

Date de publication:
Feb 2019
Historique:
entrez: 19 11 2018
pubmed: 19 11 2018
medline: 9 3 2019
Statut: ppublish

Résumé

Medical therapy for hypertrophic cardiomyopathy (HCM) has focused on minimizing the impact of symptoms due to left ventricular outflow tract obstruction and diastolic dysfunction. This article briefly discusses currently available therapy and focuses on both clinically available medications with novel applications for HCM as well as novel medications under development with specific indication for HCM. Finally, a brief summary of the current gaps and potential targets for pharmacotherapy is discussed.

Identifiants

DOI: 10.1016/j.ccl.2018.08.008 PMID: 30447712
pubmed: 30447712
pii: S0733-8651(18)30867-1
doi: 10.1016/j.ccl.2018.08.008
pii:
doi:

Substances chimiques

Adrenergic beta-Antagonists 0
Calcium Channel Blockers 0
Cardiotonic Agents 0

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

113-117

Informations de copyright

Copyright © 2018 Elsevier Inc. All rights reserved.

Auteurs

Timothy C Wong (TC)

Department of Medicine, Division of Cardiology, University of Pittsburgh School of Medicine, UPMC Hypertrophic Cardiomyopathy Center, UPMC Heart and Vascular Institute, 200 Lothrop Street, Pittsburgh, PA 15213, USA. Electronic address: wongtc@upmc.edu.

Matthew Martinez (M)

Division of Cardiology, Lehigh Valley Health Network, 1250 South Cedar Crest Boulevard, Suite 300, Allentown, PA 18103, USA.

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Classifications MeSH

questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Effets physiologiques des médicaments › Agents neuromédiateurs › Agents adrénergiques › Antagonistes adrénergiques › Antagonistes bêta-adrénergiques › Novel Pharmacotherapy for Hypertrophic Cardiomyopathy.
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Agents cardiovasculaires › Inhibiteurs des canaux calciques › Novel Pharmacotherapy for Hypertrophic Cardiomyopathy.
questionsmedicales.fr › Maladies cardiovasculaires › Cardiopathies › Valvulopathies › Maladie de la valve aortique › Cardiomyopathie hypertrophique › Novel Pharmacotherapy for Hypertrophic Cardiomyopathy.
questionsmedicales.fr › Actions chimiques et utilisations › Utilisations spécialisées de produits chimiques › Agents protecteurs › Cardiotoniques › Novel Pharmacotherapy for Hypertrophic Cardiomyopathy.
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Caractéristiques des études épidémiologiques › Études cliniques comme sujet › Essais cliniques comme sujet › Novel Pharmacotherapy for Hypertrophic Cardiomyopathy.
questionsmedicales.fr › Sciences sociales › Prévision › Novel Pharmacotherapy for Hypertrophic Cardiomyopathy.
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Novel Pharmacotherapy for Hypertrophic Cardiomyopathy.
questionsmedicales.fr › Thérapeutique › Traitement médicamenteux › Utilisation hors indication › Novel Pharmacotherapy for Hypertrophic Cardiomyopathy.
questionsmedicales.fr › Qualité, accès, évaluation des soins de santé › Assurance de la qualité des soins de santé › Recommandations comme sujet › Guides de bonnes pratiques cliniques comme sujet › Novel Pharmacotherapy for Hypertrophic Cardiomyopathy.