Effects of
ATP Binding Cassette Transporter, Subfamily B
/ genetics
Adult
Aged
Analgesics, Opioid
/ pharmacokinetics
Asian People
Base Sequence
Drug Administration Schedule
Drug Dosage Calculations
Female
Gene Expression
Genotype
Heterozygote
Homozygote
Humans
Lung Neoplasms
/ ethnology
Male
Middle Aged
Neoplasm Grading
Pain
/ physiopathology
Pain Measurement
Polymorphism, Single Nucleotide
Receptors, Opioid, mu
/ genetics
Sufentanil
/ pharmacokinetics
ABCB1 gene
Radical cancer
Single nucleotide polymorphism
Sufentanil
μ-opioid receptor gene
Journal
Bioscience reports
ISSN: 1573-4935
Titre abrégé: Biosci Rep
Pays: England
ID NLM: 8102797
Informations de publication
Date de publication:
31 01 2019
31 01 2019
Historique:
received:
20
07
2018
revised:
14
11
2018
accepted:
15
11
2018
pubmed:
21
11
2018
medline:
28
7
2019
entrez:
21
11
2018
Statut:
epublish
Résumé
To study the effects of single-nucleotide polymorphisms of the A total of 225 Chinese Han nationality patients undergoing thoracoscopic-assisted radical resection of lung cancer were enrolled in the present study. Among them, 132 were males (58.67%) and 93 (41.33%) were females having American Society of Anesthesiologists statuses classified as grades I or II. The rs1799971, rs563649 and rs1323040 genotypes of the The sufentanil doses at T1, T2 and T3 were significantly higher in radical-operation lung cancer patients with mutant homozygous rs1799971 and rs1323040 loci in the The rs1799971 and rs1323040 polymorphisms of the
Identifiants
pubmed: 30455395
pii: BSR20181211
doi: 10.1042/BSR20181211
pmc: PMC6328871
pii:
doi:
Substances chimiques
ABCB1 protein, human
0
ATP Binding Cassette Transporter, Subfamily B
0
Analgesics, Opioid
0
OPRM1 protein, human
0
Receptors, Opioid, mu
0
Sufentanil
AFE2YW0IIZ
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Informations de copyright
© 2019 The Author(s).
Références
Pharmacology. 2014;94(5-6):273-9
pubmed: 25500932
Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2015 Sep;159(3):341-6
pubmed: 24993742
Hum Mol Genet. 2009 Mar 15;18(6):1037-51
pubmed: 19103668
J Thorac Oncol. 2016 Dec;11(12):2066-2081
pubmed: 27575423
Transl Psychiatry. 2015 Apr 28;5:e558
pubmed: 25918995
J Pharmacol Sci. 2013;121(1):48-57
pubmed: 23257656
Pharmacogenomics. 2017 Oct;18(15):1387-1391
pubmed: 28976288
Mol Psychiatry. 2017 Mar;22(3):346-352
pubmed: 28115739
Cancer Chemother Pharmacol. 2017 Jun;79(6):1179-1186
pubmed: 28447211
Anesthesiology. 2002 Apr;96(4):913-20
pubmed: 11964599
Zhongguo Fei Ai Za Zhi. 2016 Jan;19(1):1-15
pubmed: 26805732
Crit Care Med. 2013 Apr;41(4):999-1008
pubmed: 23385102
Ther Drug Monit. 2006 Oct;28(5):707-11
pubmed: 17038891
Eur J Clin Pharmacol. 2013 Sep;69(9):1651-8
pubmed: 23686330
Proc Natl Acad Sci U S A. 1998 Aug 4;95(16):9608-13
pubmed: 9689128
Ther Drug Monit. 2004 Apr;26(2):180-5
pubmed: 15228162
Cytometry. 1998 Jun 1;32(2):86-94
pubmed: 9627221
Am J Transplant. 2003 Apr;3(4):477-83
pubmed: 12694072
Genet Test Mol Biomarkers. 2013 Oct;17(10):743-9
pubmed: 23909491
Physiol Res. 2015;64 Suppl 4:S529-38
pubmed: 26681083
Cancer Cell Int. 2013 May 20;13(1):46
pubmed: 23687985
Clin Pharmacol Ther. 2007 Apr;81(4):539-46
pubmed: 17192767