Evidence for protein kinase involvement in the 5-HT-[Ca


Journal

Experimental physiology
ISSN: 1469-445X
Titre abrégé: Exp Physiol
Pays: England
ID NLM: 9002940

Informations de publication

Date de publication:
02 2019
Historique:
received: 12 10 2018
accepted: 19 11 2018
pubmed: 21 11 2018
medline: 1 8 2019
entrez: 21 11 2018
Statut: ppublish

Résumé

What is the central question of this study? The mammalian carotid body (CB) is a peripheral chemoreceptor organ involved in O Chemoreceptor (type I) cells of the rodent carotid body (CB) synthesize and release several neurotransmitters/neuromodulators, including 5-hydroxytryptamine (5-HT), implicated in enhanced CB excitation after exposure to chronic intermittent hypoxia, e.g. sleep apnoea. However, recent studies suggest that 5-HT can robustly stimulate adjacent glial-like type II cells via ketanserin-sensitive 5-HT

Identifiants

pubmed: 30456914
doi: 10.1113/EP087411
doi:

Substances chimiques

Connexins 0
Nerve Tissue Proteins 0
Neurotransmitter Agents 0
pannexin 1, rat 0
Serotonin 333DO1RDJY
Cyclic AMP-Dependent Protein Kinases EC 2.7.11.11
Protein Kinase C EC 2.7.11.13
Calcium SY7Q814VUP

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Pagination

244-253

Subventions

Organisme : CIHR
ID : MOP 142469
Pays : Canada

Informations de copyright

© 2018 The Authors. Experimental Physiology © 2018 The Physiological Society.

Auteurs

Erin M Leonard (EM)

Department of Biology, McMaster University, Hamilton, Ontario, Canada.

Min Zhang (M)

Department of Biology, McMaster University, Hamilton, Ontario, Canada.

Colin A Nurse (CA)

Department of Biology, McMaster University, Hamilton, Ontario, Canada.

Articles similaires

Robotic Surgical Procedures Animals Humans Telemedicine Models, Animal

Odour generalisation and detection dog training.

Lyn Caldicott, Thomas W Pike, Helen E Zulch et al.
1.00
Animals Odorants Dogs Generalization, Psychological Smell
Animals TOR Serine-Threonine Kinases Colorectal Neoplasms Colitis Mice
Animals Tail Swine Behavior, Animal Animal Husbandry

Classifications MeSH