Database establishment for the secondary fungal DNA barcode
base de données d’un code à barres fongique secondaire
codage à barres de l’ADN fongique
facteur d’élongation de la traduction 1α
fungal DNA barcoding
secondary fungal DNA barcode database
translational elongation factor 1α
Journal
Genome
ISSN: 1480-3321
Titre abrégé: Genome
Pays: Canada
ID NLM: 8704544
Informations de publication
Date de publication:
Mar 2019
Mar 2019
Historique:
pubmed:
23
11
2018
medline:
6
8
2019
entrez:
23
11
2018
Statut:
ppublish
Résumé
With new or emerging fungal infections, human and animal fungal pathogens are a growing threat worldwide. Current diagnostic tools are slow, non-specific at the species and subspecies levels, and require specific morphological expertise to accurately identify pathogens from pure cultures. DNA barcodes are easily amplified, universal, short species-specific DNA sequences, which enable rapid identification by comparison with a well-curated reference sequence collection. The primary fungal DNA barcode, ITS region, was introduced in 2012 and is now routinely used in diagnostic laboratories. However, the ITS region only accurately identifies around 75% of all medically relevant fungal species, which has prompted the development of a secondary barcode to increase the resolution power and suitability of DNA barcoding for fungal disease diagnostics. The translational elongation factor 1α (
Identifiants
pubmed: 30465691
doi: 10.1139/gen-2018-0083
doi:
Substances chimiques
DNA, Fungal
0
DNA, Ribosomal Spacer
0
Peptide Elongation Factor 1
0
Types de publication
Journal Article
Langues
eng