Structure elucidation of ostreocin-A and ostreocin-E1, novel palytoxin analogs produced by the dinoflagellate Ostreopsis siamensis, using LC/Q-TOF MS.


Journal

Bioscience, biotechnology, and biochemistry
ISSN: 1347-6947
Titre abrégé: Biosci Biotechnol Biochem
Pays: England
ID NLM: 9205717

Informations de publication

Date de publication:
Mar 2019
Historique:
pubmed: 27 11 2018
medline: 14 3 2019
entrez: 27 11 2018
Statut: ppublish

Résumé

Palytoxin analogs are marine toxins with large complex polyol structures. A benthic dinoflagellate Ostreopsis siamensis produces more than ten palytoxins (ostreocins, OSTs). The limited sample availability of minor OSTs restricts the definition of their chemical structures. The present investigation characterizes structures of two minor OSTs, i.e., ostreocin-A (OSTA) and ostreocin-E1 (OSTE1), using ostreocin-D (OSTD) as a reference compound, by liquid chromatography/quadrupole-time-of-flight mass spectrometry. The molecular formulas of OSTA and OSTE1 were C

Identifiants

pubmed: 30475097
doi: 10.1080/09168451.2018.1550356
doi:

Substances chimiques

Acrylamides 0
Cnidarian Venoms 0
palytoxin OQ17NC0MOV

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

381-390

Auteurs

Takehito Terajima (T)

a Department of Food and Nutrition Science, Graduate School of Agriculture , Tokyo University of Agriculture , Setagaya , Tokyo , Japan.

Hideaki Uchida (H)

b Japan Customer Service Operation , Agilent Technologies Japan, Ltd , Hachioji, Tokyo , Japan.

Naoki Abe (N)

a Department of Food and Nutrition Science, Graduate School of Agriculture , Tokyo University of Agriculture , Setagaya , Tokyo , Japan.

Takeshi Yasumoto (T)

c Tama Laboratory , Japan Food Research Laboratories , Tama, Tokyo , Japan.

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Classifications MeSH