Coupling effects of thiol and urea-type groups for promotion of oxidative protein folding.
Journal
Chemical communications (Cambridge, England)
ISSN: 1364-548X
Titre abrégé: Chem Commun (Camb)
Pays: England
ID NLM: 9610838
Informations de publication
Date de publication:
15 Jan 2019
15 Jan 2019
Historique:
pubmed:
7
12
2018
medline:
5
2
2019
entrez:
4
12
2018
Statut:
ppublish
Résumé
Coupling of thiol and urea-type -NHC([double bond, length as m-dash]X)NH2 (X = O or NH) groups is effective in promoting oxidative protein folding. In particular, a thiol compound coupled with a guanidyl (X = NH) group significantly accelerates the rates of folding processes and enhances the yields of native proteins.
Substances chimiques
Proteins
0
Sulfhydryl Compounds
0
Urea
8W8T17847W
Glutathione
GAN16C9B8O
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM