Benefits of multiple micronutrient supplementation in heart failure: A comprehensive review.


Journal

Critical reviews in food science and nutrition
ISSN: 1549-7852
Titre abrégé: Crit Rev Food Sci Nutr
Pays: United States
ID NLM: 8914818

Informations de publication

Date de publication:
2019
Historique:
pubmed: 7 12 2018
medline: 30 10 2019
entrez: 4 12 2018
Statut: ppublish

Résumé

Multiple micronutrient supplementation has been suggested to have a role on health outcomes in patients with heart failure (HF), but the evidence is inconclusive. To elucidate the role of multiple micronutrient supplementation in heart failure we performed a comprehensive review of the literature. The search in databases included PUBMED (until June 2018) to detect randomized controlled trials (RCTs) and meta-analyzes that investigated the impact of micronutrient supplementation in HF. With more than 2357 titles and abstracts reviewed, we included only the studies suitable for the final review. Whether alone or in combination, micronutrients have been found to improve the health outcomes of patients with HF by improving symptoms, work capacity and left ventricular ejection fraction (LVEF), thus increasing the quality of life in these patients. Future studies are needed to document the effects of multiple micronutrient associations in order to include them in nutritional guidelines to increase survival and to improve quality of life in patients with heart failure.

Sections du résumé

BACKGROUND BACKGROUND
Multiple micronutrient supplementation has been suggested to have a role on health outcomes in patients with heart failure (HF), but the evidence is inconclusive.
OBJECTIVE OBJECTIVE
To elucidate the role of multiple micronutrient supplementation in heart failure we performed a comprehensive review of the literature.
METHODS AND RESULTS RESULTS
The search in databases included PUBMED (until June 2018) to detect randomized controlled trials (RCTs) and meta-analyzes that investigated the impact of micronutrient supplementation in HF.
RESULTS RESULTS
With more than 2357 titles and abstracts reviewed, we included only the studies suitable for the final review. Whether alone or in combination, micronutrients have been found to improve the health outcomes of patients with HF by improving symptoms, work capacity and left ventricular ejection fraction (LVEF), thus increasing the quality of life in these patients.
CONCLUSION CONCLUSIONS
Future studies are needed to document the effects of multiple micronutrient associations in order to include them in nutritional guidelines to increase survival and to improve quality of life in patients with heart failure.

Identifiants

pubmed: 30507249
doi: 10.1080/10408398.2018.1540398
doi:

Substances chimiques

Amino Acids 0
Fatty Acids, Omega-3 0
Micronutrients 0
Vitamins 0
Homocysteine 0LVT1QZ0BA
Ubiquinone 1339-63-5
Taurine 1EQV5MLY3D
Folic Acid 935E97BOY8
coenzyme Q10 EJ27X76M46
Selenium H6241UJ22B
Magnesium I38ZP9992A
Potassium RWP5GA015D
Carnitine S7UI8SM58A

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

965-981

Auteurs

Simona Dragan (S)

a Department of Cardiology, Discipline of Preventive Cardiology , "Victor Babes" University of Medicine and Pharmacy , Timisoara , Romania.

Florina Buleu (F)

a Department of Cardiology, Discipline of Preventive Cardiology , "Victor Babes" University of Medicine and Pharmacy , Timisoara , Romania.

Ruxandra Christodorescu (R)

b Department of Internal Medicine, Discipline of Medical Semiology II , "Victor Babes" University of Medicine and Pharmacy , Timisoara , Romania.

Florin Cobzariu (F)

a Department of Cardiology, Discipline of Preventive Cardiology , "Victor Babes" University of Medicine and Pharmacy , Timisoara , Romania.

Stela Iurciuc (S)

a Department of Cardiology, Discipline of Preventive Cardiology , "Victor Babes" University of Medicine and Pharmacy , Timisoara , Romania.

Dana Velimirovici (D)

a Department of Cardiology, Discipline of Preventive Cardiology , "Victor Babes" University of Medicine and Pharmacy , Timisoara , Romania.

Jianbo Xiao (J)

c Institute of Chinese Medical Sciences , University of Macau , Taipa , China.

Constantin Tudor Luca (CT)

d Department of Cardiology, Discipline of Cardiology II , "Victor Babes" University of Medicine and Pharmacy , Timisoara , Romania.

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Classifications MeSH