The glycerophosphocholine acyltransferase Gpc1 is part of a phosphatidylcholine (PC)-remodeling pathway that alters PC species in yeast.

Acylation Acyltransferases / chemistry Glycerylphosphorylcholine / metabolism Phosphatidylcholines / chemistry Saccharomyces cerevisiae / enzymology Saccharomyces cerevisiae Proteins / chemistry
Ale1 Gpc1 acyltransferase glycerophosphocholine lipid remodeling membrane turnover phosphatidylcholine phospholipid metabolism yeast

Journal

The Journal of biological chemistry
ISSN: 1083-351X
Titre abrégé: J Biol Chem
Pays: United States
ID NLM: 2985121R

Informations de publication

Date de publication:
25 01 2019
Historique:
received: 07 08 2018
revised: 27 11 2018
pubmed: 6 12 2018
medline: 30 4 2019
entrez: 6 12 2018
Statut: ppublish

Résumé

Phospholipase B-mediated hydrolysis of phosphatidylcholine (PC) results in the formation of free fatty acids and glycerophosphocholine (GPC) in the yeast

Identifiants

DOI: 10.1074/jbc.RA118.005232 PMID: 30514764 PMC: PMC6349126
pubmed: 30514764
pii: S0021-9258(20)38857-8
doi: 10.1074/jbc.RA118.005232
pmc: PMC6349126
pii:
doi:

Substances chimiques

Phosphatidylcholines 0
Saccharomyces cerevisiae Proteins 0
Glycerylphosphorylcholine 60M22SGW66
Acyltransferases EC 2.3.-
glycerophosphocholine acyltransferase, S cerevisiae EC 2.3.-

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S.

Langues

eng

Sous-ensembles de citation

IM

Pagination

1189-1201

Subventions

Organisme : NIGMS NIH HHS
ID : R15 GM104876
Pays : United States

Informations de copyright

© 2019 Anaokar et al.

Références

J Biol Chem. 1994 Apr 1;269(13):9833-41
pubmed: 8144575
J Biol Chem. 2005 Nov 18;280(46):38290-6
pubmed: 16172116
Chem Phys Lipids. 2014 May;180:23-43
pubmed: 24418527
Biotechniques. 1992 Jul;13(1):18-20
pubmed: 1503765
J Biol Chem. 2007 Oct 19;282(42):30562-9
pubmed: 17726007
Mol Biol Cell. 2012 Apr;23(7):1146-56
pubmed: 22323296
J Biol Chem. 2016 Nov 25;291(48):25066-25076
pubmed: 27758859
Proc Natl Acad Sci U S A. 2009 Feb 17;106(7):2136-41
pubmed: 19174513
FEBS Lett. 2018 Jun;592(11):1829-1836
pubmed: 29782033
Lipids. 2016 Jan;51(1):15-23
pubmed: 26643989
J Biol Chem. 2005 Oct 28;280(43):36110-7
pubmed: 16141200
J Lipid Res. 2014 May;55(5):799-807
pubmed: 24646950
J Biol Chem. 2007 Sep 28;282(39):28344-52
pubmed: 17652094
J Biol Chem. 2007 Oct 19;282(42):30845-55
pubmed: 17675291
Anal Chem. 2006 Feb 1;78(3):779-87
pubmed: 16448051
Curr Genet. 2006 Dec;50(6):367-75
pubmed: 16924500
J Biol Chem. 2017 Nov 10;292(45):18729-18730
pubmed: 29127205
J Biol Chem. 2001 Feb 9;276(6):3756-63
pubmed: 11078727
Yeast. 1998 Jul;14(10):953-61
pubmed: 9717241
J Biol Chem. 1994 Aug 5;269(31):19725-30
pubmed: 8051052
J Biol Chem. 2014 Nov 7;289(45):31591-604
pubmed: 25258318
Chem Biol. 2015 Mar 19;22(3):412-25
pubmed: 25794437
J Biol Chem. 2009 Dec 25;284(52):36034-46
pubmed: 19841481
Genetics. 2015 Oct;201(2):525-42
pubmed: 26245832
Lipid Insights. 2016 Jan 19;8(Suppl 1):33-40
pubmed: 26819558
Planta. 2015 Feb;241(2):347-58
pubmed: 25298156
Annu Rev Biochem. 1965;34:313-46
pubmed: 14321173
Biochemistry. 2003 Mar 18;42(10):3054-9
pubmed: 12627972
Yeast. 2005 Jun;22(8):601-13
pubmed: 16034810
Prog Lipid Res. 2015 Jul;59:147-71
pubmed: 26165797
PLoS One. 2012;7(4):e35063
pubmed: 22529973
Biochim Biophys Acta. 2013 Jun;1831(6):1167-76
pubmed: 23501167
Cell Cycle. 2012 Dec 15;11(24):4499-506
pubmed: 23114620
Biochim Biophys Acta. 2008 Aug;1781(8):391-9
pubmed: 18599377
Nucleic Acids Res. 2000 Apr 1;28(7):1499-505
pubmed: 10710415
Biochim Biophys Acta. 2007 Mar;1771(3):337-42
pubmed: 16781190
Yeast. 1994 Nov;10(11):1429-37
pubmed: 7871882
Metabolites. 2011 Dec 1;1(1):21-40
pubmed: 22905337
Genetics. 1998 Aug;149(4):1707-15
pubmed: 9691030
Curr Biol. 2009 Dec 1;19(22):R1046-52
pubmed: 19948145
Nucleic Acids Res. 2010 Aug;38(14):4768-77
pubmed: 20385592
Mol Microbiol. 2014 Feb;91(4):736-50
pubmed: 24329598
Yeast. 1995 Oct;11(13):1265-74
pubmed: 8553697
J Biol Chem. 1981 Jul 10;256(13):7077-85
pubmed: 7016881
J Biol Chem. 2007 Dec 21;282(51):36853-61
pubmed: 17951629
FEMS Yeast Res. 2014 May;14(3):369-88
pubmed: 24520995
J Biol Chem. 1998 Jul 3;273(27):16635-8
pubmed: 9642212
Biochem Biophys Res Commun. 2014 Mar 7;445(2):289-93
pubmed: 24491568
J Biol Chem. 2006 Aug 11;281(32):22773-85
pubmed: 16777854
Annu Rev Biochem. 2011;80:859-83
pubmed: 21275641
Nucleic Acids Res. 2001 May 1;29(9):e45
pubmed: 11328886
J Biol Chem. 1987 Nov 15;262(32):15428-35
pubmed: 2445736
Eukaryot Cell. 2003 Aug;2(4):729-36
pubmed: 12912892
Proc Natl Acad Sci U S A. 2003 Feb 18;100(4):1745-50
pubmed: 12576545
Dev Cell. 2014 Jun 23;29(6):729-39
pubmed: 24960695
FEBS Lett. 2018 Apr;592(8):1330-1345
pubmed: 29265372
Biochim Biophys Acta. 2013 Mar;1831(3):523-32
pubmed: 23010477
J Neurochem. 2011 Mar;116(5):813-9
pubmed: 21214562
Prog Lipid Res. 2014 Jan;53:18-81
pubmed: 24125941
FEBS Lett. 2007 Nov 27;581(28):5511-6
pubmed: 17996202
Methods. 2001 Dec;25(4):402-8
pubmed: 11846609
J Biol Chem. 1960 Aug;235:2233-7
pubmed: 14413818
J Mol Biol. 2016 Dec 4;428(24 Pt A):4776-4791
pubmed: 27534816
Genetics. 2001 Dec;159(4):1491-9
pubmed: 11779791
J Lipid Res. 2008 Aug;49(8):1794-806
pubmed: 18430972
Genetics. 2012 Feb;190(2):317-49
pubmed: 22345606
J Biol Chem. 2007 Nov 23;282(47):34288-98
pubmed: 17890783
FEMS Yeast Res. 2012 Nov;12(7):796-808
pubmed: 22780918

Auteurs

Sanket Anaokar (S)

Departments of Biological Sciences, Pittsburgh, Pennsylvania 15282.

Ravindra Kodali (R)

Chemistry and Biochemistry, Duquesne University, Pittsburgh, Pennsylvania 15282.

Benjamin Jonik (B)

Departments of Biological Sciences, Pittsburgh, Pennsylvania 15282.

Mike F Renne (MF)

Department of Membrane Biochemistry & Biophysics, Bijvoet Center and Institute of Biomembranes, 3584 CH Utrecht, The Netherlands.

Jos F H M Brouwers (JFHM)

Department of Biochemistry and Cell Biology, Institute of Biomembranes, Utrecht University, 3584 CH Utrecht, The Netherlands.

Ida Lager (I)

Department of Plant Breeding, Swedish University of Agricultural Sciences, SE-230 53 Alnarp, Sweden.

Anton I P M de Kroon (AIPM)

Department of Membrane Biochemistry & Biophysics, Bijvoet Center and Institute of Biomembranes, 3584 CH Utrecht, The Netherlands.

Jana Patton-Vogt (J)

Departments of Biological Sciences, Pittsburgh, Pennsylvania 15282. Electronic address: pattonvogt@duq.edu.

Articles similaires

Membrane potential stimulates ADP import and ATP export by the mitochondrial ADP/ATP carrier due to its positively charged binding site.

Vasiliki Mavridou, Martin S King, Andre Bazzone et al.
1.00
Adenosine Triphosphate Adenosine Diphosphate Mitochondrial ADP, ATP Translocases Binding Sites Mitochondria

Saccharomyces cerevisiae whole cell biotransformation for the production of aldehyde flavors and fragrances.

Nazreen V M Abdul Muthaliff, Yao Zong Ng, Wei Mei Guo et al.
1.00
Saccharomyces cerevisiae Aldehydes Biotransformation Flavoring Agents Lipoxygenase

The dual life of disordered lysine-rich domains of snoRNPs in rRNA modification and nucleolar compaction.

Carine Dominique, Nana Kadidia Maiga, Alfonso Méndez-Godoy et al.
1.00
Saccharomyces cerevisiae Lysine Cell Nucleolus RNA, Ribosomal Saccharomyces cerevisiae Proteins

Minimisation of metabolic networks defines a new functional class of genes.

Giorgio Jansen, Tanda Qi, Vito Latora et al.
1.00
Metabolic Networks and Pathways Saccharomyces cerevisiae Computational Biology Synthetic Biology Computer Simulation

Classifications MeSH

questionsmedicales.fr › Métabolisme › Acylation › The glycerophosphocholine acyltransferase Gpc1...
questionsmedicales.fr › Enzymes et coenzymes › Enzymes › Transferases › Acyltransferases › The glycerophosphocholine acyltransferase Gpc1...
questionsmedicales.fr › Lipides › Lipides membranaires › Phospholipides › Glycérophosphate › Acides phosphatidiques › Glycérophospholipides › Phosphatidylcholines › Glycerylphosphorylcholine › The glycerophosphocholine acyltransferase Gpc1...
questionsmedicales.fr › Lipides › Lipides membranaires › Phospholipides › Glycérophosphate › Acides phosphatidiques › Glycérophospholipides › Phosphatidylcholines › The glycerophosphocholine acyltransferase Gpc1...
questionsmedicales.fr › Eucaryotes › Champignons › Levures › Saccharomyces › Saccharomyces cerevisiae › The glycerophosphocholine acyltransferase Gpc1...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines fongiques › Protéines de Saccharomyces cerevisiae › The glycerophosphocholine acyltransferase Gpc1...