HLA discrepancy between graft and host rather than that graft and first donor impact the second transplant outcome.
Adolescent
Adult
Aged
Female
Follow-Up Studies
Graft vs Host Disease
/ immunology
HLA Antigens
/ immunology
Hematologic Neoplasms
/ immunology
Hematopoietic Stem Cell Transplantation
/ mortality
Histocompatibility Testing
Humans
Male
Middle Aged
Neoplasm Recurrence, Local
/ immunology
Prognosis
Retrospective Studies
Survival Rate
Tissue Donors
/ supply & distribution
Transplantation Conditioning
Transplantation, Homologous
Young Adult
Journal
Haematologica
ISSN: 1592-8721
Titre abrégé: Haematologica
Pays: Italy
ID NLM: 0417435
Informations de publication
Date de publication:
05 2019
05 2019
Historique:
received:
20
08
2018
accepted:
23
11
2018
pubmed:
14
12
2018
medline:
21
5
2020
entrez:
8
12
2018
Statut:
ppublish
Résumé
Second allogeneic hematopoietic stem cell transplantation is a curative treatment option for patients with hematologic malignancies. However, it is unclear whether HLA discrepancy between graft and first donor has an impact on the outcome of second transplantation. We retrospectively analyzed 646 patients receiving second transplantation after an initial HLA mismatched transplantation. With regard to graft-
Identifiants
pubmed: 30523056
pii: haematol.2018.204438
doi: 10.3324/haematol.2018.204438
pmc: PMC6518881
doi:
Substances chimiques
HLA Antigens
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
1055-1061Informations de copyright
Copyright© 2019 Ferrata Storti Foundation.
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