Serratia marcescens sepsis outbreak caused by contaminated propofol.
Cross Infection
/ epidemiology
Disease Outbreaks
Drug Contamination
Electrophoresis, Gel, Pulsed-Field
/ methods
Female
Humans
Male
Microbial Sensitivity Tests
/ methods
Middle Aged
Propofol
/ adverse effects
Sepsis
/ epidemiology
Serratia Infections
/ epidemiology
Serratia marcescens
/ pathogenicity
Syringes
Extrinsic contamination
Outbreak
Propofol
Serratia marcescens
Journal
American journal of infection control
ISSN: 1527-3296
Titre abrégé: Am J Infect Control
Pays: United States
ID NLM: 8004854
Informations de publication
Date de publication:
05 2019
05 2019
Historique:
received:
04
08
2018
revised:
17
10
2018
accepted:
17
10
2018
pubmed:
12
12
2018
medline:
22
4
2020
entrez:
12
12
2018
Statut:
ppublish
Résumé
We presented a sepsis outbreak caused by Serratia marcescens from contaminated propofol to raise awareness. Three patients had sepsis syndrome after chest surgery. Isolation of S marcescens from patients' respiratory and blood samples alerted us to a possible outbreak. Four syringes filled with propofol and 1 saline solution yielded S marcescens. Nine of 10 isolates from samples of patients and environment genotyped by pulsed-field gel electrophoresis were the same. Disobeying aseptic injection rules of propofol is still causing outbreaks.
Identifiants
pubmed: 30527282
pii: S0196-6553(18)31028-9
doi: 10.1016/j.ajic.2018.10.014
pii:
doi:
Substances chimiques
Propofol
YI7VU623SF
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
582-584Informations de copyright
Copyright © 2018 Association for Professionals in Infection Control and Epidemiology, Inc. Published by Elsevier Inc. All rights reserved.